Protein C News and Research

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Laureate enters agreement with AVEO to produce AV-203 monoclonal antibody against ErbB3

Laureate Pharma, Inc., a full-service contract development and manufacturing organization, announced today that they have entered into a development and manufacturing agreement to produce AV-203, AVEO Pharmaceutical's (Cambridge, MA) novel monoclonal antibody targeted against ErbB3.

28 Oct 2010

Scientists suggest E-cadherin can function as oncogene in some cancers

Researchers at Mayo Clinic in Florida have found that a molecule long believed to be a beneficial tumor suppressor and thus a potential cancer drug target appears to act as an oncogene in some lethal brain tumors.

28 Oct 2010

Scientists determine tertiary structure of TehA membrane protein in Haemophilus bacteria

Proteins are molecular machines that transport substances, catalyze chemical reactions, pump ions, and identify signaling substances. They are chains of amino acids and the individual amino acid sequence is known for many of them. However, the functions a protein can carry out inside the cell are determined by the three-dimensional spatial structure of the protein. Establishing this so-called tertiary structure presents a great challenge to scientists.

28 Oct 2010

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Today in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.

28 Oct 2010

Ipsen reports 8.3% increase in Group sales for first nine months of 2010

Ipsen reported today its sales for the third quarter and the first nine months of 2010.

28 Oct 2010

Elevated amounts of SP2 protein turn stem cells into cancerous tumors: Research

Researchers at North Carolina State University have found that the overproduction of a key protein in stem cells causes those stem cells to form cancerous tumors. Their work may lead to new treatments for a variety of cancers.

28 Oct 2010

B. Braun initiates voluntary recall of heparin injection products

B. Braun Medical Inc. was recently notified by its supplier, Scientific Protein Laboratories LLC (SPL), of a nationwide recall of a lot of Heparin Sodium USP Active Pharmaceutical Ingredient (API) sold to B. Braun because additional testing of retained crude heparin samples used by SPL to manufacture this single API lot indicated a trace amount of oversulfated chondroitin sulfate (OSCS) contaminant.

From B. Braun Melsungen AG 28 Oct 2010

New oral drug shrinks IMT sarcoma driven by abnormally activated protein

A new oral drug caused dramatic shrinkage of a patient's rare, aggressive form of soft-tissue cancer that was driven by an abnormally activated protein, physician-scientists from Dana-Farber Cancer Institute report in the Oct. 28 issue of the New England Journal of Medicine.

28 Oct 2010

New findings suggest way to treat lung diseases

A new study of an exotic, infectious virus that has caused three recent outbreaks in the United States reveals clues to how the virus might damage lungs during infection. The findings also suggest possible new ways to treat lung diseases in humans.

28 Oct 2010

Prolonged use of glucosamine linked to greater risk of developing diabetes

High doses or prolonged use of glucosamine causes the death of pancreatic cells and could increase the risk of developing diabetes, according to a team of researchers at Universit- Laval's Faculty of Pharmacy. Details of this discovery were recently published on the website of the Journal of Endocrinology.

28 Oct 2010

IBI receives U.S. patent for novel blood protein biomarkers

Intrinsic Bioprobes today announced that the United States Patents and Trademark Office has issued US Patent 7,816,095 covering novel blood protein biomarkers related to cardiovascular disease. This patent is first of a series of patent applications that cover specific human protein variants as biomarkers with clinical utility.

28 Oct 2010

GTC 2010 third fiscal quarter net loss decreases to $4.5 million from $26.2 million

GTC Biotherapeutics, Inc. today reported its financial results for the third fiscal quarter ended September 30, 2010.

28 Oct 2010

BioSilta releases EnPresso tablet that regulates protein production in recombinant bacteria

BioSilta announces the release of the EnPresso Tablet Cultivation Set, a tabletised form of the patented EnBase technology. The EnBase technology is based on providing an enzymatic-controlled glucose supply in a fed-batch type manner, which allows an extended growth period and promotes higher final cell density.

27 Oct 2010

Tips to maintain healthy weight through Halloween and holidays

For many people, the scariest part of every Halloween is not a visit from ghouls and ghosts, but the chocolaty temptation of crunchy candy bars and sweet treats that surround us in stores, at work - even in our own homes. And sometimes it can be just too hard to resist. In fact, the average American will spend more than $20 on candy treats this Halloween, according to the National Retail Federation's 2010 Halloween Consumer Intentions and Actions Survey.

27 Oct 2010

Scientists discover MSMB protein in urine can predict prostate cancer risk

British scientists have identified a protein in urine that can help indicate which patients are at an increased risk of developing prostate cancer. The Cancer Research UK Cambridge Research Institute and The Institute of Cancer Research found that the level of MSMB protein in urine could provide a fast and accurate prostate cancer diagnosis for doctors and patients, potentially replacing the currently painful and more costly approach a blood sample.

27 Oct 2010

Scripps Florida scientist receives grant from Landenberger Foundation for HIV research

A scientist on the Florida campus of The Scripps Research Institute has received funding from the Philadelphia-based Margaret Q. Landenberger Research Foundation.

27 Oct 2010

Anti-enolase antibody may contribute to bile duct injury in biliary atresia: Research

Researchers at the University of Colorado School of Medicine and The Children's Hospital have taken a big step toward understanding what causes one of the most serious liver diseases in infants.

27 Oct 2010

Study: lncRNA are involved in host response to viral infection

Scientists have demonstrated for the first time that a certain class of RNA (known as long non-protein-coding RNA [lncRNA]) are involved in the host response to viral infection. These findings, published today in the online journal mBio-, could greatly change the way scientists look at the body's response to viral infection.

27 Oct 2010

Elan 2010 third quarter total revenue decreases 2% to $281.4 million

Elan Corporation, plc today reported its third quarter and first nine months 2010 financial results.

27 Oct 2010

Reactivating three silenced molecules may provide new strategy to treat multiple myeloma

New research links three molecules to a critical tumor suppressor gene that is often turned off in multiple myeloma, a presently incurable cancer of the blood.

27 Oct 2010

Protein C News and Research

Laureate enters agreement with AVEO to produce AV-203 monoclonal antibody against ErbB3

Scientists suggest E-cadherin can function as oncogene in some cancers

Scientists determine tertiary structure of TehA membrane protein in Haemophilus bacteria

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

Ipsen reports 8.3% increase in Group sales for first nine months of 2010

Elevated amounts of SP2 protein turn stem cells into cancerous tumors: Research

B. Braun initiates voluntary recall of heparin injection products

New oral drug shrinks IMT sarcoma driven by abnormally activated protein

New findings suggest way to treat lung diseases

Prolonged use of glucosamine linked to greater risk of developing diabetes

IBI receives U.S. patent for novel blood protein biomarkers

GTC 2010 third fiscal quarter net loss decreases to $4.5 million from $26.2 million

BioSilta releases EnPresso tablet that regulates protein production in recombinant bacteria

Tips to maintain healthy weight through Halloween and holidays

Scientists discover MSMB protein in urine can predict prostate cancer risk

Scripps Florida scientist receives grant from Landenberger Foundation for HIV research

Anti-enolase antibody may contribute to bile duct injury in biliary atresia: Research

Study: lncRNA are involved in host response to viral infection

Elan 2010 third quarter total revenue decreases 2% to $281.4 million

Reactivating three silenced molecules may provide new strategy to treat multiple myeloma

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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