Bacterial News and Research

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Scientists investigate active plasma metabolite of remdesivir in SARS-CoV-2 mouse model

Using mouse models, scientists have investigated the active plasma metabolite of remdesivir, GS-441 524, and hydroxychloroquine as possible drug candidates in COVID-19. The research shows GS-441 524 could be an effective therapeutic drug against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while at the same time discounting hydroxychloroquine as a reliable anti-viral.

20 Sep 2020

Ineffective immune responses may be responsible for COVID-19 mortality rates in men and the elderly

News-Medical speaks to Dr. Nicole Lieberman about her latest research that discovered delayed immune responses may affect COVID-19 mortality rates.

18 Sep 2020

Study shows how fiber shapes the structure of plant cell walls

The secret of how fibre shapes the structure of plant cell walls has been revealed, with potentially wide-ranging applications ranging from nutrition and health to agriculture.

18 Sep 2020

New method quickly shows how antibiotics combine to stop bacterial growth

Researchers at Uppsala University have developed a new method to determine - rapidly, easily and cheaply - how effective two antibiotics combined can be in stopping bacterial growth.

17 Sep 2020

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use in treating pneumonia, binds to the receptors that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to in human cells.

17 Sep 2020

Study shows why bacterial cells behave differently on different types of surfaces

These results from studies in both experimental and theoretical physics may help to improve antibacterial surfaces. The research work was recently published in the journal 'Nanoscale'.

17 Sep 2020

Azelastine antihistamine inhibits SARS-CoV-2 infection in nasal tissue in vitro

In a study published on the bioRxiv preprint server, researchers from the University of Pécs, University of Vienna, and CEBINA GmbH, Vienna, show the ability of the antihistamine azelastine to inhibit SARS-CoV-2 infection in human nasal tissue in vitro.

16 Sep 2020

Study highlights role of specific protein in the mass production of antibodies

Antibodies play a fundamental role in medicine, and antibody-mediated immune response is the ultimate target in the quest for a vaccine to defeat the current pandemic.

16 Sep 2020

COVID-19 works with the body's microbiota to increase disease severity in obese and diabetic patients

The combined effects of the body's microbiota working together with COVID-19 in the lungs could explain the severity of the disease in people with obesity and diabetes, according to a new article published today in eLife.

15 Sep 2020

Bacterial movement is powered by tiny protein motor

The ability to move is key for bacteria like some strains of salmonella and E. coli to efficiently spread infections. They can propel themselves forward using threads, known as flagella, powered by the flagellar rotary motor.

15 Sep 2020

Immune system study helps illuminate a surprising mind-body connection

New research at Washington University School of Medicine in St. Louis helps illuminate a surprising mind-body connection.

14 Sep 2020

Heat and gut microbiota promote stronger bones

Osteoporosis, a bone disease linked to ageing, is characterized by a loss of bone density, micro-architectural deterioration of the bones and an increased risk of fractures.

11 Sep 2020

Effective, simple, safe self-amplifying RNA vaccines

A recent review paper in the journal Current Opinion in Virology in September 2020 shows how a new generation of RNA vaccines called self-amplifying RNA vaccines are more potent than conventional mRNA vaccines and could hold the key to the global production of cost-effective potent COVID-19 vaccines.

11 Sep 2020

CityU produces graphene face masks with excellent anti-bacterial efficiency

Face masks have become an important tool in fighting against the COVID-19 pandemic. However, improper use or disposal of masks may lead to "secondary transmission".

10 Sep 2020

Scientists claim serious data discrepancies in RaTG13 sequence

Even as the COVID-19 pandemic enters its ninth month, scientists continue to debate the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) intensely. A new preprint published in September 2020 discusses the current issues with the bat coronavirus (CoV) strain that is often considered to have very close homology with the above-mentioned virus, concluding that there are inadequate grounds to consider it to be the ancestral pool of SARS-CoV-2.

10 Sep 2020

An ingestible capsule for sampling of gut microbiota and biomarkers

Gut microbes affect human health, but there is still much to learn, in part because they're not easy to collect.

9 Sep 2020

Allergic immune response against bacteria is not pathological but protective

Allergy is one of the most common diseases in Europe, it is estimated that more than 150 million Europeans suffer from recurring allergies and by 2025 this could have increased to half of the entire European population.

9 Sep 2020

Researchers receive $1.9 million federal grant to find Lyme disease vaccine

Pesky, yet dangerous ticks are no longer latching exclusively onto hunters and outdoor enthusiasts. Milder winters and disrupted habitats have driven them out of the woods, with Lyme disease cases in the United States tripling since the late 1990s.

9 Sep 2020

Gut microbiota composition and function not related to onset of gestational diabetes

Maternal overweight and obesity increase the risk of gestational diabetes mellitus. Gut microbiota composition has recently been associated with both overweight and a range of metabolic diseases.

9 Sep 2020

Memory B cells indicate durable immunity in COVID-19

Now a new study by researchers at SUNY Upstate Medical University and published recently on the preprint server medRxiv in September 2020 shows that memory B cells are upregulated in convalescent COVID-19 patients, correlating with a better immune response and shorter symptom duration.

8 Sep 2020