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Genetically modified herpes virus can be used in the fight against cancer

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

1 Jun 2022

New findings reveal potential mechanisms for cellular defects in human laminopathies

A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the Proceedings of the National Academy of Sciences.

1 Jun 2022

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

A 28-patient phase 1 gene therapy clinical trial for the degenerative retinal disease Leber hereditary optic neuropathy (LHON) found no significant safety concerns; however, treatment failed to improve or slow vision loss, with even the highest dose. LHON affects the optic nerve, which carries visual signals from the light-sensing retina to the brain.

1 Jun 2022

SARS-CoV-2 variation within individual hosts holds largely untapped information that may enhance the resolution of transmission inferences

Researchers assessed the variation of SARS-CoV-2 within hosts.

1 Jun 2022

Tracking the emergence of potential drug-resistant mutations in SARS-CoV-2 proteins

Researchers hypothesized that the emergence of resistant SARS-CoV-2 variants can be anticipated by identifying possible escape mutations already present in the existing SARS-CoV-2 populations.

1 Jun 2022

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

A recent article illustrated the structural and biochemical characteristics of the processing of SARS-CoV-2 polyproteins by Mpro.

1 Jun 2022

Study investigates an outbreak of SARS-CoV-2 among children and adults after attending an overnight summer camp

Researchers investigated a SARS-CoV-2 outbreak among individuals who attended an overnight summer camp in Texas in June 2021.

1 Jun 2022

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

seqWell today announced a partnership with Element Biosciences Inc., developer of the Element AVITI™ System.

From Element Biosciences 1 Jun 2022

Researchers discover how a workhorse protein keeps protein production on track

Cells produce proteins like little factories. But if they make too much at the wrong times it can lead to diseases like cancer, so they control production with a process called RNA interference (RNAi).

31 May 2022

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

Researchers compared the performance of a highly multiplexed mass spectrometry-based commercial assay to identify SARS-CoV-2 variants.

31 May 2022

Evidence on COVID-19 vaccine effectiveness and duration of protection against Omicron

Researchers reported the vaccine effectiveness and duration of immunity against SARS-CoV-2 Omicron.

31 May 2022

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

The loss of genome heterogeneity in CoVs leads to high viral fitness variants that adapt to the human host.

31 May 2022

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers demonstrated the sarbecovirus open reading frame 7a (ORF7a)-induced hindrance of the antigen presentation by the major histocompatibility complex class I (MHC-I) in hosts.

30 May 2022

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

A recent study published in The Lancet Microbe described the case of a non-vaccinated female coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 subvariants.

30 May 2022

Investigating post-COVID complaints after Delta versus Omicron variant infections

A new study discusses whether infection with the SARS-CoV-2 Omicron variant increases the risk of post-COVID complaints Delta infection.

30 May 2022

Fast-breeding sea urchin species could open new avenues for genetic research

Many people may not realize that the humble sea urchin is a titan when it comes to the study of biology. Now, researchers from Japan have discovered that sea urchins could help biological studies go further than ever before.

29 May 2022

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Biological arms races are commonplace in nature. Cheetahs, for example, have evolved a sleek body form that lends itself to rapid running, enabling them to feast upon similarly speedy gazelles, the fastest of which may evade predation.

27 May 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Researchers discover bifunctional lipopeptide antibiotic with a low resistance potential

Through bioinformatic prospecting, researchers discovered and synthesized a novel, naturally inspired bifunctional lipopeptide antibiotic with a low resistance potential.

27 May 2022

SARS-CoV-2 genome analysis could boost disease surveillance

Continued monitoring of the evolution of the virus that causes COVID-19 as the pandemic progresses could strengthen disease surveillance systems and aid preparedness for new variants, a study suggests.

27 May 2022

Genome News and Research

Genetically modified herpes virus can be used in the fight against cancer

New findings reveal potential mechanisms for cellular defects in human laminopathies

Gene therapy for degenerative retinal disease has no safety concerns but fails to improve vision loss

SARS-CoV-2 variation within individual hosts holds largely untapped information that may enhance the resolution of transmission inferences

Tracking the emergence of potential drug-resistant mutations in SARS-CoV-2 proteins

Structural and biochemical traits of main protease-mediated SARS-CoV-2 polyprotein processing

Study investigates an outbreak of SARS-CoV-2 among children and adults after attending an overnight summer camp

seqWell and Element Biosciences partner to demonstrate sequencing performance of multiplexed plexWell technology with the AVITI System

Researchers discover how a workhorse protein keeps protein production on track

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

Evidence on COVID-19 vaccine effectiveness and duration of protection against Omicron

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

Investigating post-COVID complaints after Delta versus Omicron variant infections

Fast-breeding sea urchin species could open new avenues for genetic research

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Understanding transposons provides a new starting point to generate more powerful gene editing tools

Researchers discover bifunctional lipopeptide antibiotic with a low resistance potential

SARS-CoV-2 genome analysis could boost disease surveillance

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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