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Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Oligomerix, Inc., a privately held company pioneering the development of tau oligomer inhibitors for Alzheimer's disease and related neurodegenerative disorders, and the Feinstein Institutes for Medical Research announced today the publication of preclinical data demonstrating that an oral small molecule drug inhibits the formation of neurotoxic tau oligomers in an animal model of tau aggregation most relevant to AD.

26 Nov 2019

Community-based clinics and clinicians play key role in reshaping LGBT mental health care

New research reveals that community-based clinics and clinicians play an essential role in reshaping both mental health care for LGBT people and broader attitudes about sexuality and gender.

25 Nov 2019

Gut microbes can tamp down or boost the severity of norovirus infection

The highly contagious norovirus causes diarrhea and vomiting and is notorious for spreading rapidly through densely populated spaces, such as cruise ships, nursing homes, schools and day care centers. Each year, it is responsible for some 200,000 deaths, mostly in the developing world.

25 Nov 2019

FDA approves Ohio State-developed drug to treat patients with CLL and SCL

On Nov. 21, 2019, the U.S. Food and Drug Administration approved the use of the drug acalabrutinib for first-line therapy in chronic lymphocytic leukemia and small cell lymphoma.

22 Nov 2019

Higher antibiotic exposure linked to increased risk of Parkinson's disease

Higher exposure to commonly used oral antibiotics is linked to an increased risk of Parkinson's disease according to a recently published study by researchers form the Helsinki University Hospital, Finland.

22 Nov 2019

Using behavioral sciences to promote oral health

2019 marks the Centennial of the Journal of Dental Research. Over the last century the JDR has been dedicated to the dissemination of new knowledge and information on all sciences relevant to dentistry and to the oral cavity and associated structures in health and disease.

22 Nov 2019

Study: 34% of high schools in the U.S. do not have access to athletic trainer services

Despite ongoing tragedies in sports as well as research from a host of sources – including the American Academy of Pediatrics – which state schools with athletic trainers (ATs) have lower injury rates, a study released today showed that 34% of public and private high schools, have no access to athletic trainers in the United States.

21 Nov 2019

Medi-Cal to expand eligibility to young undocumented adults. But will they enroll?

Starting in January, young adults can sign up for California's Medicaid program regardless of immigration status.

21 Nov 2019

Six ways physicians can help optimize reproductive health in women with epilepsy

Worldwide, more than 15 million women of childbearing age have epilepsy. Each year about 600,000 of them become pregnant.

20 Nov 2019

Penn Nursing receives $100,000 grant for HIV research

Penn Nursing has received a $100,000 grant from the Robert I. Jacobs Fund of the Philadelphia Foundation for HIV research. The grant supports an investigation, "Youth-driven Perspectives in HIV Biomedical Prevention and Cure Research," led by José A. Bauermeister, PhD, MPH, Presidential Professor of Nursing.

20 Nov 2019

ETVAX vaccine candidate shows promise against enterotoxigenic E. coli diarrhea

University of Gothenburg reports first successful results of the oral, inactivated vaccine candidate ETVAX against enterotoxigenic E. coli diarrhea in a placebo-controlled phase I/II study in infants and children from 6 months to 5 years of age in Bangladesh.

20 Nov 2019

New California law may expand use of HIV prevention drugs, with caveats

Kellen Willhite was 24 when he learned he'd been exposed to HIV. What followed was, as he describes it, a second trauma: trying to obtain the drugs that could save him before it was too late.

20 Nov 2019

New drug 'ubrogepant' may work for migraine

A new study published in the November 19, 2019 issue of JAMA shows that a newly developed small molecule drug called ubrogepant may successfully fight migraine at doses of 25 and 50 mg, with pain relief at 2 hours with both doses, while the most troublesome symptom of migraine was held off at 2 hours post-dose with the 50 mg dose. This may help millions of migraine patients to achieve pain relief and function better.

19 Nov 2019

Oral vaccination with cholera toxin helps counteract age-associated obesity

Here the research team tested a safe and well-established microbe-based immune adjuvant to restore immune homeostasis and counteract inflammation-associated obesity in animal models.

19 Nov 2019

MIT researchers develop method to isolate T cells primed for certain allergies or infections

When your immune system is exposed to a vaccine, an allergen, or an infectious microbe, subsets of T cells that can recognize a foreign intruder leap into action.

19 Nov 2019

Mysterious feather duvet lung disease nearly kills a man

A soft pillow and a warm duvet are all you need to have a soothing and relaxing sleep, especially during the frigid season. However, a man from the United Kingdom nearly died because of a mysterious illness related to a duvet. It was later found out by doctors that the culprit for his lung disease is his newly-bought feather duvet.

19 Nov 2019

Researchers propose a novel method to underscore the benefits of HPV vaccine

Health campaigns on social media aimed at increasing human papillomavirus (HPV) vaccination may see greater success, according to Drexel University researchers, if they inject a narrative into information-based posts.

19 Nov 2019

How HIV self-testing affects diagnosis and behaviour in MSM

Men who have sex with men (MSMs) are among the most high-risk groups for acquiring and transmitting HIV infection. A new study published in the journal JAMA Internal Medicinesays that the rate of detection of new infections is more than doubled when self-testing is available. This could increase access to early treatment and thus interrupt the chain of transmission among MSMs.

18 Nov 2019

New clinical guideline for treatment of drug-resistant tuberculosis published

The American Thoracic Society, Centers for Disease Control and Prevention, European Respiratory Society and the Infectious Diseases Society of America have published an official clinical guideline on the treatment of drug-resistant tuberculosis in the Nov. 15 American Journal of Respiratory and Critical Care Medicine.

18 Nov 2019

Clinical trial: Oral drug improves exercise capacity in teens with congenital heart defects

The largest-ever clinical trial of a medication for pediatric cardiology patients found that an oral drug significantly improved exercise capacity in adolescent patients with severe, congenital single-ventricle heart defects.

17 Nov 2019

Oral News and Research

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Community-based clinics and clinicians play key role in reshaping LGBT mental health care

Gut microbes can tamp down or boost the severity of norovirus infection

FDA approves Ohio State-developed drug to treat patients with CLL and SCL

Higher antibiotic exposure linked to increased risk of Parkinson's disease

Using behavioral sciences to promote oral health

Study: 34% of high schools in the U.S. do not have access to athletic trainer services

Medi-Cal to expand eligibility to young undocumented adults. But will they enroll?

Six ways physicians can help optimize reproductive health in women with epilepsy

Penn Nursing receives $100,000 grant for HIV research

ETVAX vaccine candidate shows promise against enterotoxigenic E. coli diarrhea

New California law may expand use of HIV prevention drugs, with caveats

New drug 'ubrogepant' may work for migraine

Oral vaccination with cholera toxin helps counteract age-associated obesity

MIT researchers develop method to isolate T cells primed for certain allergies or infections

Mysterious feather duvet lung disease nearly kills a man

Researchers propose a novel method to underscore the benefits of HPV vaccine

How HIV self-testing affects diagnosis and behaviour in MSM

New clinical guideline for treatment of drug-resistant tuberculosis published

Clinical trial: Oral drug improves exercise capacity in teens with congenital heart defects

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