Genetic News and Research

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Onchocerciasis parasite shows signs of resistance

Onchocerciasis is an infection caused by Onchocerca volvulus, a parasite nematode worm transmitted to humans by a species of black fly of the Simulium genus whose larvae develop in fast-flowing rivers.

31 Jan 2008

Accelerated head growth a risk factor for autism

Children with autism have normal-size heads at birth but develop accelerated head growth between six and nine months of age, a period that precedes the onset of many behaviors that enable physicians to diagnose the developmental disorder, according to new research from the University of Washington's Autism Center.

31 Jan 2008

Why your fertility cells must have 'radio silence'

Researchers in Kobe, Japan, and Montreal, Canada, have uncovered a previously unknown mechanism which causes embryonic germ cells which later develop into sperm or ova to go through a period of "transcriptional silence," during which information from the cell's DNA cannot be copied.

31 Jan 2008

Exposure to secondhand smoke linked to worsening of lung function in cystic fibrosis sufferers

Exposure to secondhand smoke is associated with adverse effects on lung function among persons with cystic fibrosis, with this effect being worse for persons with certain gene variations, according to a study in the January 30 issue of JAMA.

31 Jan 2008

Kidney cancer drug attacks a major type of acute myeloid leukemia

A drug used to treat kidney cancer also targets a genetic mutation active in about one third of patients with acute myeloid leukemia (AML), the most common and lethal form of adult leukemia, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan. 29 edition of the Journal of the National Cancer Institute.

30 Jan 2008

Direct sequencing of single RNA strands with tip-enhanced Raman spectroscopy

The genetic alphabet contains four letters. Although our cells can readily decipher our genetic molecules, it isn't so easy for us to read a DNA sequence in the laboratory. Scientists require complex, highly sophisticated analytical techniques to crack individual DNA codes.

28 Jan 2008

Medical Research Council and GSK to identify new therapeutic targets from genetic association studies

The Medical Research Council (MRC) and GlaxoSmithKline (GSK) have announced the creation of a jointly funded programme seeking to identify and validate genes associated with common human diseases. A key aim of the programme will be to translate these observations into new drug targets and biomarkers of disease.

28 Jan 2008

Telepathic genes recognize similarities in each other

Genes have the ability to recognise similarities in each other from a distance, without any proteins or other biological molecules aiding the process, according to new research published this week in the Journal of Physical Chemistry B.

25 Jan 2008

Search for the 'on' switches may reveal genetic role in development and disease

A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Duke's Institute for Genome Sciences & Policy (IGSP).

25 Jan 2008

Researchers unravel mystery of cell division

Experts in mitosis (cell division) at the University of Virginia Health System have made discoveries that explain how one protein the kinase Aurora B could have such a large role in guiding and policing the process of cell division.

25 Jan 2008

New MIT tool probes brain circuits

Researchers at the Picower Institute for Learning and Memory at MIT report in the Jan. 24 online edition of Science that they have created a way to see, for the first time, the effect of blocking and unblocking a single neural circuit in a living animal.

25 Jan 2008

Mental and physical stimulation delays dementia in Huntington's disease

Scientists at Melbourne's Howard Florey Institute have discovered that mental and physical stimulation delays the onset of dementia in the fatal genetic disease, Huntington's disease.

25 Jan 2008

Researchers identify five genes with possible protective capabilities against a Parkinson's disease trait

University of Alabama researchers have identified five genes within animal models displaying protective capabilities against a hallmark trait of Parkinson's disease.

25 Jan 2008

Evolutionary 'battle scars' identify enhanced antiviral activity

Rapid evolution of a protein produced by an immunity gene is associated with increased antiviral activity in humans, a finding that suggests evolutionary biology and virology together can accelerate the discovery of viral-defense mechanisms, according to researchers at Fred Hutchinson Cancer Research Center.

25 Jan 2008