Immune System News and Research

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Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

A team of international scientists has recently characterized the structure of tumor necrosis factor receptor associated factor 6 (TRAF6) N-terminal domain for therapeutic purposes.

28 Feb 2023

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

The number of specialized immune cells available for fighting skin cancer doubled when a new treatment blocked their escape from melanoma tumors, experiments in mice and human cells show.

27 Feb 2023

Using sweat to diagnosis disease: soft microfluidic analysis systems assess health status

Researchers explored microfluidic systems with a skin interface in assessing chemical exposure and health status.

27 Feb 2023

Virus encounter educates human immune system, says study

A study conducted by researchers at the University of Liège on group 2 innate lymphoid cells (or ILC2s) shows that the functional reprogramming of these cells following their exposure to viruses allows our body to react differently to exposure to certain respiratory allergens. This study is published in Science Immunology.

25 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Researchers successfully grow electrodes in living tissues

The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body's molecules as triggers.

24 Feb 2023

University of Vermont Cancer Center to offer a novel, highly effective form of cancer treatment

The University of Vermont Cancer Center will offer a novel, highly effective form of cancer treatment called CAR T-cell therapy beginning in February, when final accreditation and approval to begin treating patients is expected.

24 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Cedars-Sinai investigators found that women who developed mood and anxiety disorders associated with pregnancy and childbirth had specific altered proteins circulating in their bloodstream in the third trimester.

23 Feb 2023

Skipping meals can trigger a negative effect on immune cells

Fasting may be detrimental to fighting off infection, and could lead to an increased risk of heart disease, according to a new study by the Icahn School of Medicine at Mount Sinai.

23 Feb 2023

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer's disease and to lower cholesterol.

23 Feb 2023

Preventative antibiotic given during labor can reduce the risk of sepsis and death

A single oral dose of the antibiotic azithromycin given during labor can dramatically reduce the risk of sepsis and death among women following childbirth, according to a large multi-country clinical trial, as a UN report warns of "stagnation" in maternal health.

23 Feb 2023

UTA professor leads a CPRIT-funded study to better craft a personalized cancer immunotherapy

A University of Texas at Arlington bioengineering professor is leading a state-funded project that will try to identify what T-cells are detecting in cancerous cells to better craft a personalized cancer immunotherapy.

23 Feb 2023

Review: Immunomodulatory therapies and nutritional significance of Ganoderma lucidum

According to the research published in Food & Functions recently, a team led by Prof. Huang Qing at the Institute of Intelligent Machines, Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Sciences (CAS), reported for the first time an update and a comprehensive summary of the studies on the immunomodulatory therapies and nutritional significance of Ganoderma lucidum (G. lucidum) from 2010 to 2022, and confirmed that G. lucidum is an essential prebiotic for increasing bacterial flora and a health encouraging agent because of its components, primarily its abundant source of polysaccharides, triterpenoids, and polyphenols.

22 Feb 2023

What is the impact of outdoor air pollution on COVID-19 mortality?

Researchers assess the impact of outdoor air pollution on COVID-19 mortality.

22 Feb 2023

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

LMU physician uncovers mechanisms behind immune system immaturity in prematurely born infants

LMU physician Markus Sperandio has discovered why the immune system of prematurely born babies is not working properly after birth.

22 Feb 2023

When cancer research turns to the immune system – the critical role of peptides and immunopeptidomics

In this interview, AZoM speaks to Rohan Thakur, the President of Life Science Mass Spectrometry at Bruker, about what the opportunities of the market are and how Bruker is planning on rising to the challenge.

From Bruker Daltonics 22 Feb 2023

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

21 Feb 2023

First molecular biomarker for acquired generalized lipodystrophy discovered

Researchers at UT Southwestern Medical Center have discovered the first molecular biomarker for acquired generalized lipodystrophy (AGL), a rare disorder in which fat deposits are destroyed, causing patients to have dangerously low body fat, signs of accelerated aging, and severe metabolic diseases including diabetes and fatty liver.

21 Feb 2023

Immune System News and Research

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

Using sweat to diagnosis disease: soft microfluidic analysis systems assess health status

Virus encounter educates human immune system, says study

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers successfully grow electrodes in living tissues

University of Vermont Cancer Center to offer a novel, highly effective form of cancer treatment

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

Study finds protein biomarkers in women with perinatal mood and anxiety disorder symptoms

Skipping meals can trigger a negative effect on immune cells

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Preventative antibiotic given during labor can reduce the risk of sepsis and death

UTA professor leads a CPRIT-funded study to better craft a personalized cancer immunotherapy

Review: Immunomodulatory therapies and nutritional significance of Ganoderma lucidum

What is the impact of outdoor air pollution on COVID-19 mortality?

Scientists identify mechanisms underlying autoimmunity in Down syndrome

LMU physician uncovers mechanisms behind immune system immaturity in prematurely born infants

When cancer research turns to the immune system – the critical role of peptides and immunopeptidomics

First induced bat iPSCs offer insights into the close relationship between bats and SARS-CoV-2 viruses

First molecular biomarker for acquired generalized lipodystrophy discovered

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