Protein C News and Research

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Statin therapy reduces cardiovascular disease risk in patients with high sensitivity C-reactive protein

People at intermediate risk of cardiovascular disease who have high levels of high sensitivity C-reactive protein (hsCRP), a blood marker for inflammation, could benefit from cholesterol-lowering therapy even if their cholesterol is already at desirable levels.

25 Aug 2010

ARAMARK Education launches wellness, nutrition education program for school children

With millions of students heading back to school, the childhood obesity crisis and nutrition legislation continues to top the agenda in Washington, the medical community, and for educators, parents and guardians across the country.

25 Aug 2010

CRT, Bayer Schering Pharma partner to study new leptin antagonist peptides in gynaecological, oncological diseases

Cancer Research Technology has signed an agreement with Bayer Schering Pharma AG, Germany to evaluate new leptin antagonist peptides as potential experimental treatments initially in the area of gynaecological diseases, including cancer.

25 Aug 2010

Study identifies four genetic variants associated with ESRD disease in Chinese diabetic patients

Examination of a gene involved in cell signaling finds that four common variants of this gene are associated with the development of end-stage renal disease in Chinese patients with type 2 diabetes, according to a study in the August 25 issue of JAMA.

25 Aug 2010

CMC Biologics completes new, disposable manufacturing facility at Seattle

CMC Biologics, a Contract Manufacturing Organization with manufacturing sites in Europe and the USA, today announced the completion of a new state-of-the-art disposable manufacturing facility at its Seattle, WA site. The addition comes as part of a staged major expansion plan, which will add significant production capacity to its existing facility to accommodate a growing demand for cGMP manufacture of biopharmaceuticals.

25 Aug 2010

New TRIM5α-based treatments can knock out HIV in humans: Research

Using a $225,000 microscope, researchers have identified the key components of a protein called TRIM5α that destroys HIV in rhesus monkeys.The finding could lead to new TRIM5α-based treatments that would knock out HIV in humans, said senior researcher Edward M. Campbell, PhD, of Loyola University Health System.

25 Aug 2010

Increasing levels of neuropeptide Y, receptors can counteract seizures: Research

Research in recent years has shown that the brain tries to counteract seizures. One of the ways it does this is by increasing levels of a protein-like molecule called neuropeptide Y and the expression of certain receptors for it.

25 Aug 2010

Researchers identify molecular signals that impact male fertility: Research

Male infertility is a common medical problem, affecting millions of men in the United States annually. Its causes include an inability to make productive sperm. Now, using yeast as a model organism, researchers at the University of Pennsylvania School of Medicine are beginning to identify the molecular signals that could in part underlie that problem.

25 Aug 2010

BioScale installs ViBE analytical tool at Massachusetts-based pharmaceutical company

BioScale Inc., an innovative life science company that develops, manufactures and promotes novel analytical tools enabling advancements in protein research, today announced the first shipment and installation of the ViBE™ Protein Analysis Workstation at a major Massachusetts-based pharmaceutical company.

25 Aug 2010

Scientists discover influence of vitamin D in genes linked with autoimmune diseases

UK scientists at the University of Oxford have discovered that vitamin D can affect the activity of more than 200 genes of cells grown in the lab. Some of these genes are known from previous studies to be involved in diseases like diabetes and cancer.

24 Aug 2010

Ensemble Therapeutics showcases data on new drug discovery platform at ACS National Meeting

Ensemble Therapeutics announced today the presentation of data on its macrocyclic-based drug discovery platform at the American Chemical Society National Meeting August 22-26, in Boston at the Boston Convention and Exposition Center.

24 Aug 2010

Aileron Therapeutics, Roche partner to develop, commercialise Stapled Peptide Therapeutics

Aileron Therapeutics and Roche announced today that they have entered into a collaboration to discover, develop and commercialise a new class of drugs called Stapled Peptide Therapeutics. As part of this agreement, Roche will work with Aileron to develop drug candidates against up to five undisclosed targets selected from Roche's key therapeutic areas, which include oncology, virology, inflammation, metabolism and CNS.

24 Aug 2010

Pressure BioSciences collaborates with LBNL to analyze microbe for oil spill clean-up

Pressure BioSciences, Inc. today announced a collaboration with the Lawrence Berkeley National Laboratory ("LBNL"). Scientists at LBNL are using the Company's pressure cycling technology ("PCT") platform in studies aimed at improving the analysis of microorganisms in environments with low biomass, such as oil reservoirs or deep sea oil plumes from oil spills.

24 Aug 2010

'Pre-vascularization' of device prior to implantation sustains circulation and suppresses scar formation

By creating a unique system of blood vessels that is engineered to interact with the tissue surrounding an implanted device, the longevity and function of these devices may be better preserved, according to a study led by researchers in the University of Louisville/ Jewish Hospital's Cardiovascular Innovation Institute (CII).

24 Aug 2010

Discovery of Hsp90 protein's pattern of motion paves way for new drug target in cancer therapy

The protein Hsp90 plays a significant role in the survival of cells that are exposed to stress. Researchers at the Technische Universitaet Muenchen (TUM) uncovered this protein's mode of operation some time ago - but now Hsp90 has surprised even the experts with an unexpected pattern of motion. The results are published in the current online issue of the renowned science journal PNAS and may help researchers discover specific cancer medication.

24 Aug 2010

USPTO grants Taligen patent for TT30 lead product candidate

Taligen Therapeutics, a biotechnology company developing therapies that regulate the complement system to treat inflammatory and immune diseases, announced today that the U.S. Patent and Trademark Office has issued U.S. Patent No. 7,759,304, entitled "Targeting Complement Factor H For Treatment of Diseases", covering the composition of matter for its lead product candidate, TT30, a novel fusion protein that selectively binds to complement activated cells to locally regulate the complement system.

24 Aug 2010

Researchers develop new instrumentation to simplify testing patients for infectious diseases

Arizona State University researchers have demonstrated a way to dramatically simplify testing patients for infectious diseases and unhealthy protein levels.New testing instrumentation developed by Antonia Garcia and John Schneider promises to make the procedure less costly and produce results in less time.

24 Aug 2010

Research on OGF-OGFr complex helps to understand pathobiology of diseases

Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the Opioid Growth Factor (OGF, [Met5]-enkephalin) and its receptor, OGFr, a clinically important system with potent antitumor properties, has controlled entry from the cytoplasm to the nucleus. The nucleocytoplasmic passage of OGF-OGFr is critical to cell proliferation and suggests that there are hierarchical levels of nuclear import.

24 Aug 2010

Berries help aging brain stay healthy

Scientists today reported the first evidence that eating blueberries, strawberries, and acai berries may help the aging brain stay healthy in a crucial but previously unrecognized way. Their study, presented at the 240th National Meeting of the American Chemical Society (ACS), concluded that berries, and possibly walnuts, activate the brain's natural "housekeeper" mechanism, which cleans up and recycles toxic proteins linked to age-related memory loss and other mental decline.

24 Aug 2010

Epilepsy Therapy Project, EF announce recipients of New Therapy Grants Program

The Epilepsy Therapy Project (ETP) and the Epilepsy Foundation (EF) today announced the latest grant recipients of its New Therapy Grants Program, a unique joint venture of the non-profit epilepsy organizations, to advance promising epilepsy research in clinical development. The grant awards, totaling approximately $200,000 in funding, will support an experimental gene therapy that directly targets epileptogenic brain tissue, as well as an electrode system that has the potential to improve the efficacy of surgical therapies for certain epilepsy syndromes.

24 Aug 2010

Protein C News and Research

Statin therapy reduces cardiovascular disease risk in patients with high sensitivity C-reactive protein

ARAMARK Education launches wellness, nutrition education program for school children

CRT, Bayer Schering Pharma partner to study new leptin antagonist peptides in gynaecological, oncological diseases

Study identifies four genetic variants associated with ESRD disease in Chinese diabetic patients

CMC Biologics completes new, disposable manufacturing facility at Seattle

New TRIM5α-based treatments can knock out HIV in humans: Research

Increasing levels of neuropeptide Y, receptors can counteract seizures: Research

Researchers identify molecular signals that impact male fertility: Research

BioScale installs ViBE analytical tool at Massachusetts-based pharmaceutical company

Scientists discover influence of vitamin D in genes linked with autoimmune diseases

Ensemble Therapeutics showcases data on new drug discovery platform at ACS National Meeting

Aileron Therapeutics, Roche partner to develop, commercialise Stapled Peptide Therapeutics

Pressure BioSciences collaborates with LBNL to analyze microbe for oil spill clean-up

'Pre-vascularization' of device prior to implantation sustains circulation and suppresses scar formation

Discovery of Hsp90 protein's pattern of motion paves way for new drug target in cancer therapy

USPTO grants Taligen patent for TT30 lead product candidate

Researchers develop new instrumentation to simplify testing patients for infectious diseases

Research on OGF-OGFr complex helps to understand pathobiology of diseases

Berries help aging brain stay healthy

Epilepsy Therapy Project, EF announce recipients of New Therapy Grants Program

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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