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Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences.

16 Jan 2025

Tiny vesicles offer powerful new approach for cancer treatment

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Jan 2025

The Christie launches unique training program for cancer care doctors

A unique training programme for a new breed of cancer care doctors is underway at The Christie in Manchester, an international center of excellence in cancer care.

15 Jan 2025

New target identified for potential colorectal cancer treatment

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system.

15 Jan 2025

Groundbreaking trial finds levofloxacin effective against multidrug-resistant TB

A clinical trial published in the New England Journal of Medicine showed that the oral antibiotic levofloxacin taken once-daily for six months substantially reduced the risk of developing drug-resistant tuberculosis (TB), and almost halved adults' and children's risk of developing multidrug-resistant TB.

15 Jan 2025

Hormonal shifts in menopause redefine women’s microbiome and risks

Research explores how menopause-induced hormonal shifts affect the microbiome, influencing oral, gut, and urogenital health, and highlights the potential of personalized interventions to enhance well-being.

15 Jan 2025

PIN1 protein found to be a significant driver of bladder cancer

Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a lid on their growth?

15 Jan 2025

Mayo Clinic partners with Microsoft Research and Cerebras to revolutionize AI in healthcare

Mayo Clinic today unveiled separate groundbreaking collaborations with Microsoft Research and with Cerebras Systems in the field of generative artificial intelligence (AI), designed to personalize patient care, significantly accelerate diagnostic time and improve accuracy.

15 Jan 2025

Semaglutide improves glycemic control with automated insulin delivery

Semaglutide combined with automated insulin delivery enhances glucose control in type 1 diabetes, lowering insulin requirements and aiding weight management.

15 Jan 2025

Terumo Blood and Cell Technologies and FUJIFILM Irvine Scientific collaborate to accelerate T cell expansion for cell therapy developers

Terumo Blood and Cell Technologies (Terumo BCT) and FUJIFILM Irvine Scientific have announced a strategic collaboration to help accelerate T cell expansion using Fujifilm's PRIME-XV® T Cell Expansion Media on Terumo BCT’s Quantum Flex™ Cell Expansion System.

From FUJIFILM Irvine Scientific 15 Jan 2025

Study reveals how bile acids impact immunotherapy in liver cancer

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors.

15 Jan 2025

CAR-NK cells offer safer, more accessible treatment for lymphoma

A new type of cell-based immunotherapy shows promise for B-cell lymphomas and - due to innovations in manufacturing - could make future cellular immunotherapies less expensive and more accessible to patients.

15 Jan 2025

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

Ultrasensitive ctDNA detection with NeXT Personal shows 81% sensitivity in early-stage lung adenocarcinoma, improving prognostic accuracy and therapy guidance.

15 Jan 2025

New gene-editing treatment extends lifespan in mice with prion disease

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

15 Jan 2025

Overcoming limitations of traditional CVD drugs

Announcing a new publication for Acta Materia Medica journal. Cardiovascular diseases (CVDs) pose a significant threat to human health due to the high mortality and morbidity rates. Traditional drugs often have limited efficacy due to inherent constraints, such as low bioavailability and notable side effects.

15 Jan 2025

Study finds no increased glioma risk with hormone therapy use

It's not easy being a woman. Just look at the statistics. Women are more likely to have such debilitating conditions as osteoporosis, migraines, Alzheimer disease, depression, multiple sclerosis, and brain tumors. Sex hormones are often blamed. However, a new study suggests no link between hormone therapy (HT) and common brain tumors known as gliomas. Results of the study are published online today in Menopause, the journal of The Menopause Society.

15 Jan 2025

No short-term benefit found for PCT-guided antibiotic treatment in children

A groundbreaking UK study in The Lancet has examined whether an additional blood test called procalcitonin (PCT) could safely shorten the time children spend on intravenous (IV) antibiotics in hospitals.

15 Jan 2025

Research reveals inaccuracies in common gene therapy measurement technique

In a finding with implications for one of the most promising cutting-edge medical treatments, researchers evaluated several measurement techniques commonly used in gene therapy.

13 Jan 2025

Blood vessel dysfunction in brain's temporal lobes linked to mild cognitive impairment

Mild cognitive impairment is linked to blood vessel dysfunction in the brain's temporal lobes - the seat of memory - according to a new USC-led study.

13 Jan 2025

Inflammasome protects stem cells from becoming cancerous

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

13 Jan 2025