Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Ramizol drug shows promise in treatment of Clostridium difficile infections

A scientific paper released today in the Journal of Antibiotics presents the pre-clinical development of Ramizol, a first generation drug belonging to a new class of styrylbenzene antibiotics with a novel mechanism of action.

19 May 2016

More neonatal infection research could drive forward measures to reduce infant deaths

No one knows how many newborns are dying each year due to antibiotic resistant infections, because of a lack of funding to research the issue fully, Professor Mike Sharland from St George's, University London said.

19 May 2016

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica.

19 May 2016

Scientists uncover whole new way of treating antibiotic-resistant superbugs

Australian scientists may have found a way to stop deadly bacteria from infecting patients. The discovery could lead to a whole new way of treating antibiotic-resistant "superbugs". The researchers have uncovered what may be an Achilles heel on the bacteria cell membrane that could act as a potential novel drug target.

17 May 2016

Potential vaccine that resembles sugar structures may help fight against gut bacterium C. difficile

A vaccine against one of the most dangerous hospital germs may soon be available. Scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam and the Freie Universität Berlin have developed a substance that elicits an immune response against the gut bacterium Clostridium difficile.

13 May 2016

High-throughput screening can help detect multiple compounds with potent antimicrobial activity

A new study in which researchers rapidly screened more than 11,000 bioactive molecules for activity against an antibiotic-resistant strain of Klebsiella pneumoniae bacteria identified multiple compounds with potent antimicrobial activity.

12 May 2016

Scientists identify new hots pots of antibiotic resistance

Antibiotic-resistant bacteria most often are associated with hospitals and other health-care settings, but a new study indicates that chicken coops and sewage treatment plants also are hot spots of antibiotic resistance.

12 May 2016

Researchers discover true Diels-Alder enzyme on the Pacific seabed

Scientists at the Universities of Bristol and Newcastle have uncovered the secret of the 'Mona Lisa of chemical reactions' - in a bacterium that lives at the bottom of the Pacific Ocean.

12 May 2016

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics.

10 May 2016

MGH researchers develop device to rapidly diagnose health-care-associated infections

A team of Massachusetts General Hospital investigators has developed a device with the potential of shortening the time required to rapidly diagnose pathogens responsible for health-care-associated infections from a couple of days to a matter of hours.

10 May 2016

UAB hospital leads the way in improving antibiotic use

One of today's urgent health threats is antibiotic resistance, caused by inappropriate prescription and use of antibiotics, and — according to the Centers for Disease Control and Prevention — approximately 50 percent of all antibiotics prescribed in the United States are unnecessary or inappropriate, with many of them prescribed in inpatient settings.

9 May 2016

Common misconception about penicillin allergies

It's time for your primary care check-up, and the doctor asks you to list any known drug allergies. "Penicillin," you say immediately, although you can't remember actually taking the drug or having a reaction to it—it was your parents who said so. According to a Texas A&M Health Science Center allergist, many people who believe they're allergic to this antibiotic may not actually be allergic at all.

5 May 2016

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers from the Scientific Research Institute of Physical-Chemical Medicine, MIPT, the company M&S Decisions and the research department of Yandex have built a computer model of the interaction between different bacteria, and between bacteria and the gut wall.

5 May 2016

Researchers highlight how BSI infecting pathogens become more resilient

A recently published special issue of Virulence, "Bloodstream Infections", focuses on the resilience of bloodstream infections (BSI) and is endorsed by the European Study Group for Infections in Compromised Hosts of the European Society of Clinical Microbiology and Infectious Diseases.

5 May 2016

Michigan researchers use 'kidney on a chip' device to measure effect of drug doses on kidney cells

University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells.

5 May 2016

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

An estimated 30 percent of outpatient oral antibiotic prescriptions in the U.S. in 2010-2011 may have been inappropriate, findings that support the need for establishing a goal for outpatient antibiotic stewardship, according to a study appearing in the May 3 issue of JAMA.

4 May 2016

Scientists identify novel way of synthesising promising new antibiotic

A novel way of synthesising a promising new antibiotic has been identified by scientists at the University of Bristol. By expressing the genes involved in the production of pleuromutilin in a different type of fungus, the researchers were able to increase production by more than 2,000 per cent.

4 May 2016

Antibiotic treatment may allow bad bugs to flourish

Antibiotics are essential for fighting bacterial infection, but, paradoxically, they can also make the body more prone to infection and diarrhea.

3 May 2016

Promising method may help identify new antimicrobials to target CRE infection

In recent years, hospitals have reported dramatic increases in the number of cases of the highly contagious, difficult-to-treat, and often deadly antibiotic-resistant bacteria carbapenem-resistant Enterobacteriaceae (CRE). Now, investigators at Beth Israel Deaconess Medical Center have developed a promising method of identifying new antimicrobials that target these organisms. The research is published in April issue of the journal ASSAY and Drug Development Technologies.

30 Apr 2016

Gut bacteria linked to risk of bloodstream infections after chemotherapy

A new study led by researchers at the University of Minnesota and Nantes University Hospital in France shows that the bacteria in people's gut may predict their risk of life-threatening blood infections following high-dose chemotherapy.

29 Apr 2016

Antibiotic News and Research

Further Reading

Ramizol drug shows promise in treatment of Clostridium difficile infections

More neonatal infection research could drive forward measures to reduce infant deaths

Natural product darwinolide may help combat fatal MRSA infection

Scientists uncover whole new way of treating antibiotic-resistant superbugs

Potential vaccine that resembles sugar structures may help fight against gut bacterium C. difficile

High-throughput screening can help detect multiple compounds with potent antimicrobial activity

Scientists identify new hots pots of antibiotic resistance

Researchers discover true Diels-Alder enzyme on the Pacific seabed

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

MGH researchers develop device to rapidly diagnose health-care-associated infections

UAB hospital leads the way in improving antibiotic use

Common misconception about penicillin allergies

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers highlight how BSI infecting pathogens become more resilient

Michigan researchers use 'kidney on a chip' device to measure effect of drug doses on kidney cells

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

Scientists identify novel way of synthesising promising new antibiotic

Antibiotic treatment may allow bad bugs to flourish

Promising method may help identify new antimicrobials to target CRE infection

Gut bacteria linked to risk of bloodstream infections after chemotherapy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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