Pathogen News and Research

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Chinese scientists develop simple fluorescence-based assay to detect carbapenem-resistant pathogens

Carbapenems are among the "antibiotics of last resort" and can fight infections for which other drugs have long lost their effectiveness. However, even carbapenem-resistant pathogenic strains have emerged over the last decades.

25 Mar 2017

Researchers develop new lab-on-a-chip platform that aims to improve pathogen detection

Nuclear amplification testing is commonly used for pathogen detection; however, the process is currently manually intensive and complex, and requires dedicated equipment. This prevents its use in some settings, and pathogen detection in individual samples.

24 Mar 2017

Review of research on wild primates underscores importance of super-spreaders in disease transmission

An extensive review of research on wild primate social networks and parasites underscores the importance of super-spreaders, or central individuals that play an outsized role in transmission of a pathogen.

21 Mar 2017

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

A research project conducted at the University of São Paulo in Brazil in collaboration with other Brazilian research institutions and abroad has revealed new aspects of the action mechanism of organic hydroperoxide resistance (Ohr) enzyme, which enables several species of bacteria to neutralize oxidizing substances released by the defense system of the host organism, be it a plant or an animal.

21 Mar 2017

Novel technology enables systematic analysis of linear ubiquitination targets

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many different forms, either as single molecule or in the form of distinct ubiquitin chains, leading to diverse conformations and varying cellular outcomes.

20 Mar 2017

Canadian scientists join international battle against Zika virus

The spread of the Zika virus, which can cause devastating birth defects, has become a pressing public health issue in many countries. To this day, there is no vaccine to prevent and no medicine to treat Zika virus infections.

16 Mar 2017

Researchers awarded CIHR grant to investigate how Zika virus changes host cells during infection

For more than a year, Tom Hobman and his research team have devoted most of their waking hours to a headlong pursuit of knowledge about the Zika virus.

16 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

New technique opens door for biochemists to create better therapeutic antibodies

Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to destroy the invader.

14 Mar 2017

Common cold virus can cause deadly pneumonia in transplant patients, study shows

The common cold is a major source of annoyance for most of us, but new research has found that the most prevalent respiratory infection can be far worse than a stuffy nose for one sector of the population — bone marrow transplant patients.

8 Mar 2017

New computer models could help researchers to better predict side-effects of drugs

New computer models from North Carolina State University show how a variant of a common protein involved in human immune response binds to the antiviral drug abacavir, causing a severe life-threatening reaction known as the abacavir hypersensitivity syndrome

8 Mar 2017

Research provides insights on how pathogens escape process of autophagy

Our immune system has various ways to deal with threats from the outside like pathogens. One of the defence mechanisms is a process called autophagy.

3 Mar 2017

Unexpected discovery paves way for new insights in regulation of bacterial virulence

Chemists and molecular biologists have made an unexpected discovery in infection biology. The researchers can now show that two proteins that bind to one another slow down a chemical reaction central to the course of the disease in the bacteria Yersinia pseudotuberculosis.

3 Mar 2017

WHO releases first ever list of antibiotic-resistant 'priority pathogens'

The World Health Organization today published its first ever list of antibiotic-resistant “priority pathogens”—a catalogue of 12 families of bacteria that pose the greatest threat to human health.

3 Mar 2017

Sex differences in microglia activity affect pain treatment, study finds

A female brain's resident immune cells are more active in regions involved in pain processing relative to males, according to a recent study by Georgia State University researchers.

2 Mar 2017

Researchers develop testing program to study potency of vaccines for neglected tropical diseases

A new generation of vaccines for neglected tropical diseases is moving into clinical trials, and understanding the long-term stability and effectiveness of these vaccines over periods of storage is key to their success.

1 Mar 2017

Hospital room floors could be overlooked source for dissemination of pathogens, study suggests

Hospital room floors may be an overlooked source of infection, according to a study published in the March issue of the American Journal of Infection Control, the official journal of the Association for Professionals in Infection Control and Epidemiology.

28 Feb 2017

Activated T-cells promote heart failure after heart attack

Chronic inflammation after a heart attack can promote heart failure and death. University of Alabama at Birmingham researchers have now shown that activated T-cells — part of the immune system's inflammatory response — are both necessary and sufficient to produce such heart failure.

28 Feb 2017

Diagnosing Infections Through Molecules in Patient Breath

Over the past couple of decades, the analytical technology and the clinical microbiology insight needed to create a breath test for infections has seen a considerable number of advances and there are now numerous research teams focused on evaluating patient breath as a diagnostic fluid for infectious diseases. Significant challenges still need to be overcome.

From Pittcon 27 Feb 2017

Duke Health scientists identify proteins in mucous that confirm viral infection

It may seem obvious, but the key to confirming whether someone is suffering from a cold or flu virus might lie at the misery's source -- the inflamed passages of the nose and throat.

22 Feb 2017

Pathogen News and Research

Chinese scientists develop simple fluorescence-based assay to detect carbapenem-resistant pathogens

Researchers develop new lab-on-a-chip platform that aims to improve pathogen detection

Review of research on wild primates underscores importance of super-spreaders in disease transmission

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

Novel technology enables systematic analysis of linear ubiquitination targets

Canadian scientists join international battle against Zika virus

Researchers awarded CIHR grant to investigate how Zika virus changes host cells during infection

LJI researchers unravel molecular underpinnings of exhausted T cells

New technique opens door for biochemists to create better therapeutic antibodies

Common cold virus can cause deadly pneumonia in transplant patients, study shows

New computer models could help researchers to better predict side-effects of drugs

Research provides insights on how pathogens escape process of autophagy

Unexpected discovery paves way for new insights in regulation of bacterial virulence

WHO releases first ever list of antibiotic-resistant 'priority pathogens'

Sex differences in microglia activity affect pain treatment, study finds

Researchers develop testing program to study potency of vaccines for neglected tropical diseases

Hospital room floors could be overlooked source for dissemination of pathogens, study suggests

Activated T-cells promote heart failure after heart attack

Diagnosing Infections Through Molecules in Patient Breath

Duke Health scientists identify proteins in mucous that confirm viral infection

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