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Love hormone may enhance compassion of people suffering from PTSD symptoms

Oxytocin - "the love hormone" - may enhance compassion of people suffering from symptoms of post-traumatic stress disorder (PTSD), according to new study conducted at the University of Haifa and Rambam Health Care Campus: "The fact that the present study found, that Oxytocin may improvement compassion among patients with post-traumatic stress disorder toward women, provides new evidence that oxytocin may be able to improve the social behavior of these patients," said Professor Simone Shamay-Tsoory from the Department of Psychology at the University of Haifa, who led the study.

11 Mar 2016

Popular kidney cancer drugs do not reduce incidence of recurrence

Two widely used targeted therapy drugs approved by the FDA for the treatment of metastatic kidney cancer—sorafenib and sunitinib—are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to a new multi-institutional study in the Lancet led by a researcher at the Abramson Cancer Center (ACC) of the University of Pennsylvania.

10 Mar 2016

Changes in gut bacteria strongly associated with PCOS-related obesity

Modifying gut bacteria could be a treatment option for some of the symptoms associated with the widespread disease polycystic ovary syndrome (PCOS), according to a recent study by San Diego State University researchers in collaboration with investigators from the University of California, San Diego.

8 Mar 2016

Patients with moderate-to-severe plaque psoriasis achieve significant improvement with ixekizumab

Eli Lilly and Company announced today that patients with moderate-to-severe plaque psoriasis who did not respond to treatment with etanercept achieved significant improvement in their psoriasis plaques when treated with ixekizumab in a Phase 3 clinical trial. Detailed results of the UNCOVER-2 study were presented during the American Academy of Dermatology Annual Meeting taking place March 4-8 in Washington, D.C.

8 Mar 2016

Xencor begins XmAb5871 Phase 2 trials in patients with IgG4-RD and Systemic Lupus Erythematosus

Xencor, Inc., a clinical-stage biopharmaceutical company developing engineered monoclonal antibodies for the treatment of autoimmune diseases, asthma and allergic diseases and cancer, today announced dosing the first patient in a Phase 2 trial of XmAb5871 in patients with IgG4-Related Disease (IgG4-RD).

8 Mar 2016

BetterYou’s DLuxPregnancy oral spray could boost vitamin D levels of expectant mums

An innovative way of boosting the vitamin D levels of expectant mums could help to improve their babies’ bone health, say health pioneers BetterYou.

From BetterYou Ltd 7 Mar 2016

New FDA approval expands use of AstraZeneca's Faslodex for women with HR+, HER2- metastatic breast cancer

AstraZeneca today announced that the US Food and Drug Administration has approved a new indication in the US, expanding the use of Faslodex (fulvestrant) to include use in combination with Ibrance (palbociclib).

7 Mar 2016

Vitamin D supplements during pregnancy do not improve babies' bone health, but may have seasonal effect

Taking vitamin D supplements during pregnancy, as recommended for all women under UK guidelines, has no significant effect on the bone density of babies, according to the first randomised controlled trial of its kind, published in The Lancet Diabetes & Endocrinology journal.

7 Mar 2016

CPAP appears to improve glycemic control in patients with OSA and type 2 diabetes

Continuous positive airway pressure, or CPAP, appears to improve glycemic control in patients with obstructive sleep apnea and type 2 diabetes that is not well controlled, according to research published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

4 Mar 2016

Steroid use in late preterm delivery can reduce rate of neonatal respiratory complications

Current recommendations are for all women who go into labor prior to 34 weeks gestation to be given antenatal corticosteroids (betamethasone) to help mature the baby's lungs. However, many babies born in the late preterm period - between 34 and 36 weeks gestation - require respiratory support at birth.

4 Mar 2016

Botulinum toxin A injections combat neuropathic pain

Botulinum toxin A injections have a sustained beneficial effect in patients with neuropathic pain, shows a randomised trial.

3 Mar 2016

UCLA study finds better method to improve recovery, reduce spread of MRSA infection

UCLA researchers have found that doctors can use a specific antibiotic in addition to surgically draining an abscess to give people a better chance of recovery. The discovery turns on its head the long-held notion that surgical drainage alone is sufficient for treating abscesses.

3 Mar 2016

Vitamin D supplementation during pregnancy can help increase bone strength in babies born in winter months

Vitamin D supplementation during pregnancy may lead to stronger bones in babies born during the winter months, a new Southampton study has shown.

2 Mar 2016

Cardiac drug combats muscle cramps in ALS

A phase II study shows that the sodium channel blocker mexiletine has no specific safety concerns in patients with amyotrophic lateral sclerosis and, moreover, markedly reduces muscle cramps.

1 Mar 2016

Phase III study: Ocrelizumab significantly reduces disease activity in PPMS patients

Ocrelizumab (OCR) is a humanized monoclonal antibody that selectively targets CD20+B cells. In a randomized, double-blind, placebo-controlled Phase III study (ORATORIO), OCR significantly reduced disease activity in patients with primary progressive multiple sclerosis (PPMS).

27 Feb 2016

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Novartis today announced that the United States Food and Drug Administration approved Afinitor (everolimus) tablets for the treatment of adult patients with progressive, well-differentiated, nonfunctional neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin that are unresectable, locally advanced or metastatic.

26 Feb 2016

Lilly announces CHMP positive opinion for ixekizumab for treatment of adults with plaque psoriasis

Eli Lilly and Company announced today that the European Medicines Agency's Committee for Medicinal Products for Human Use has issued a positive opinion for ixekizumab for the treatment of moderate-to-severe plaque psoriasis in adults in the European Union who are candidates for systemic therapy.

26 Feb 2016

Medical scientists examine potential new tool for helping prevent stroke, heart attack

Medical scientists just vetted a potentially powerful new tool for helping prevent stroke and heart attack. In a study recently published in the New England Journal of Medicine, researchers show that a drug reduced the risk of stroke or heart attack by almost a quarter in patients who had previously suffered a stroke or mini-stroke.

26 Feb 2016

Antidepressant paroxetine suppresses inflammation in people with HIV-related cognitive impairment

In a small, placebo-controlled clinical trial, Johns Hopkins physicians report that the antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment. The researchers say they believe this is the first time that a SSRI (selective serotonin reuptake inhibitor) has been shown to improve key measures of cognition in people with HIV in a controlled study.

26 Feb 2016

Researchers explore effects of attention bias modification in adolescents with MDD

A study to be published in the March 2016 issue of the Journal of the American Academy of Child and Adolescent Psychiatry reports that adolescents with major depression who performed a computer-based task designed to shift attention from sad to neutral to positive word associations showed reductions in negative attention biases and clinician-rated depressive symptoms.

25 Feb 2016

Placebo News and Research

Love hormone may enhance compassion of people suffering from PTSD symptoms

Popular kidney cancer drugs do not reduce incidence of recurrence

Changes in gut bacteria strongly associated with PCOS-related obesity

Patients with moderate-to-severe plaque psoriasis achieve significant improvement with ixekizumab

Xencor begins XmAb5871 Phase 2 trials in patients with IgG4-RD and Systemic Lupus Erythematosus

BetterYou’s DLuxPregnancy oral spray could boost vitamin D levels of expectant mums

New FDA approval expands use of AstraZeneca's Faslodex for women with HR+, HER2- metastatic breast cancer

Vitamin D supplements during pregnancy do not improve babies' bone health, but may have seasonal effect

CPAP appears to improve glycemic control in patients with OSA and type 2 diabetes

Steroid use in late preterm delivery can reduce rate of neonatal respiratory complications

Botulinum toxin A injections combat neuropathic pain

UCLA study finds better method to improve recovery, reduce spread of MRSA infection

Vitamin D supplementation during pregnancy can help increase bone strength in babies born in winter months

Cardiac drug combats muscle cramps in ALS

Phase III study: Ocrelizumab significantly reduces disease activity in PPMS patients

Novartis announces FDA approval of Afinitor for progressive, nonfunctional neuroendocrine tumors of GI

Lilly announces CHMP positive opinion for ixekizumab for treatment of adults with plaque psoriasis

Medical scientists examine potential new tool for helping prevent stroke, heart attack

Antidepressant paroxetine suppresses inflammation in people with HIV-related cognitive impairment

Researchers explore effects of attention bias modification in adolescents with MDD

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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