Preclinical News and Research

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7th Annual PREDiCT: Tumor Models Boston summit will help scientists to improve cancer research

The 7th Annual PREDiCT: Tumor Models Boston summit will be held on July 16 – 18 2019 in Boston, MA. For its anticipated return, Tumor Models Boston rebrands alongside its sister events in San Francisco, London and Asia to become PREDiCT: Tumor Models Boston as part of the PREDiCT: Tumor Models Series.

From PREDiCT 24 Apr 2019

Exploring novel strategies to heal damage after a heart attack

For people who survive a heart attack, the days immediately following the event are critical for their longevity and long-term healing of the heart's tissue.

24 Apr 2019

Researchers engineer new molecules to help stop lung cancer

University of Texas at Dallas scientists have demonstrated that the growth rate of the majority of lung cancer cells relates directly to the availability of a crucial oxygen-metabolizing molecule.

24 Apr 2019

Mediterranean diet protects against overeating and obesity

Eat as much as you want and not gain weight? Sounds too good to be true.

23 Apr 2019

Microglia play vital role in regulating neuroinflammation, research shows

A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the central nervous system--including the retina of the eye--serve as "gatekeepers," or biosensors and facilitators, of neuroinflammation in a preclinical model of autoimmune uveitis.

23 Apr 2019

Overlooked part of cell’s internal machinery may hold key to treating acute myeloid leukemia

Many individuals forced to fight an exceptionally aggressive form of the blood cancer acute myeloid leukemia (AML) don't survive more than five years.

22 Apr 2019

Researchers create new small molecules that may combat equine encephalitis viruses

Viruses without a preventative vaccine or treatment option pose a looming threat. But for viruses in this category that have already been weaponized and are recognized as human biothreats by the Centers for Disease Control and Prevention, it's a race to find a cure.

17 Apr 2019

Study resolves sex differences in psychiatric illness risk

Male and female rats whose mother experienced a simulated viral infection during pregnancy display autism- and schizophrenia-like behaviors, according to a new follow-up study published in eNeuro.

From Society for Neuroscience 16 Apr 2019

Powerful ultra-high-field MRIs for early disease detection

The widespread adoption of magnetic resonance imaging revolutionized clinical medicine, and the revolution has not stopped. Scientists in an EU-funded project are exploring ways to make MRIs even more effective - aiming to help patients get the best possible treatment through early disease detection.

16 Apr 2019

Coagulation factor VIIa prevents bleeds in hemophilia animal models

Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well.

16 Apr 2019

The two-hit model can lead to better understanding of heart failure

Nearly half of current hospital admissions for heart failure are caused by a type of the disease with no treatment options. Cardiology researchers at UT Southwestern Medical Center are changing that reality with a fresh approach, recently published in Nature.

12 Apr 2019

Innovative drug delivery may alleviate Parkinson's symptoms and stop its progression

Parkinson's disease affects between 7 and 10 million people worldwide and the number of people diagnosed is soaring due to the ageing population.

10 Apr 2019

Plain facts about health risks of sugary drinks may offer new strategy to reduce childhood obesity

A new study at Columbia University suggests that giving mothers plain facts about the health risks of consuming sugary drinks during pregnancy and early childhood may offer a new strategy to reduce childhood obesity.

10 Apr 2019

New Innovate UK funded project aims to develop biodegradable stents

A £1.1 million project to develop biodegradable stents for patients with severe vascular disease, which affects around one million people in the UK, has started thanks to Innovate UK funding.

9 Apr 2019

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

A group of researchers from the Centro de Investigación Biomédica en Red de Enfermedades Raras, Universidad Carlos III de Madrid, the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, and the Instituto de Investigación Sanitaria Fundación Jiménez Díaz have led a study which demonstrates the viability of a gene editing strategy for recessive dystrophic epidermolysis bullosa (also known as butterfly chilidren) with the tool CRISPR/Cas9 in preclinical models with this disease.

8 Apr 2019

Varian presents first preclinical results of breakthrough cancer therapy research

At the American Association for Cancer Research Annual Meeting in Atlanta, GA, Varian, in partnership with the University of Maryland School of Medicine’s Department of Radiation Oncology and the Maryland Proton Treatment Center, presented publicly the first pre-clinical results of its research on ultra-high dose rate cancer treatments with protons.

From American Association for Cancer Research-AACR Annual Meeting 2019 8 Apr 2019

Inauguration of NIDD, the Neuroimmunology Drug Development Summit

NIDD is the industry’s first meeting dedicated to targeting neuroimmunological mechanisms in order to develop clinically efficacious therapeutics.

From Neuroimmunology Drug Development 5 Apr 2019

NIAID awards $22 million grant to develop antibody-based therapies against lethal viruses

The National Institute of Allergy and Infectious Diseases has awarded an international consortium led by Albert Einstein College of Medicine, part of Montefiore, a five-year, $22 million grant to develop antibody-based therapies against four highly lethal viruses for which there are no approved vaccines or treatments.

4 Apr 2019

Physicians Committee launches new effort to encourage people to donate organ and tissue

The Physicians Committee for Responsible Medicine--a nonprofit with more than 175,000 members including doctors, scientists, and laypeople--has launched a new effort today to encourage people to become organ and tissue donors to help scientists save human lives and reduce and replace animal experiments.

4 Apr 2019

Study: Pathogenetic downregulation of adenosine linked to restless leg syndrome

Researchers have identified a common mechanism implicating adenosine in the cause of restless leg syndrome symptoms — the periodic limb movements characteristic of RLS and the state of enhanced arousal that both disrupt sleep.

4 Apr 2019

Preclinical News and Research

7th Annual PREDiCT: Tumor Models Boston summit will help scientists to improve cancer research

Exploring novel strategies to heal damage after a heart attack

Researchers engineer new molecules to help stop lung cancer

Mediterranean diet protects against overeating and obesity

Microglia play vital role in regulating neuroinflammation, research shows

Overlooked part of cell’s internal machinery may hold key to treating acute myeloid leukemia

Researchers create new small molecules that may combat equine encephalitis viruses

Study resolves sex differences in psychiatric illness risk

Powerful ultra-high-field MRIs for early disease detection

Coagulation factor VIIa prevents bleeds in hemophilia animal models

The two-hit model can lead to better understanding of heart failure

Innovative drug delivery may alleviate Parkinson's symptoms and stop its progression

Plain facts about health risks of sugary drinks may offer new strategy to reduce childhood obesity

New Innovate UK funded project aims to develop biodegradable stents

Study demonstrates viability of gene editing strategy for recessive dystrophic epidermolysis bullosa

Varian presents first preclinical results of breakthrough cancer therapy research

Inauguration of NIDD, the Neuroimmunology Drug Development Summit

NIAID awards $22 million grant to develop antibody-based therapies against lethal viruses

Physicians Committee launches new effort to encourage people to donate organ and tissue

Study: Pathogenetic downregulation of adenosine linked to restless leg syndrome

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