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Researchers unravel how the brain chemical dopamine relates to schizophrenia

Researchers at the Lieber Institute for Brain Development (LIBD) believe they have solved a riddle that has challenged scientists for more than 70 years: how the brain chemical dopamine relates to schizophrenia, the often-devastating brain disorder characterized by delusional thinking, hallucinations and other forms of psychosis.

1 Nov 2022

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Researchers examined virus-virus interactions using human lung cells coinfected with two co-circulating respiratory infection-causing viruses, respiratory syncytial virus (RSV) and influenza A virus (IAV).

1 Nov 2022

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

Researchers fabricated cerebral cortical tissues in 3D and functionally integrated them into a brain lesion in mice.

1 Nov 2022

What makes some humans mosquito magnets?

Researchers explored the reasons for the greater attractiveness of some individuals to mosquitoes.

1 Nov 2022

New system to detect cancer-related markers on CTCs

Having biopsies taken and endless tests run is nobody's idea of a good time, even if it's necessary for monitoring your health.

31 Oct 2022

What are the implications of microbial ecosystems for female reproductive health?

Researchers reviewed the current understanding of the composition and temporal dynamics of microbial niches in the female reproductive tract.

31 Oct 2022

Does maternal obesity impact fetal brain development?

In a new study, researchers assessed the impact of maternal obesity on brain development in the fetus.

31 Oct 2022

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

The findings of a new study showed that the intranasal SpyCage vaccine platform can be protective against SARS-CoV-2 and may prove to be a versatile and adaptable modality for the formulation of intranasal vaccines that target respiratory pathogens.

31 Oct 2022

New insights on antibody response against SARS-CoV-2 Omiron sublineages

Knowing how well vaccination against one SARS-CoV-2 strain (with or without previous infection) counteracts infection with a different strain is a critical research question.

28 Oct 2022

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

A new study confirmed that the SARS-CoV-2 spike protein does not bind to human AChR’s orthosteric sites, nor does it compete with ACh, choline, or nicotine.

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Ancient viral DNA in human genomes protects cells against present-day viruses

Viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain present-day viruses, according to new research.

27 Oct 2022

Rutgers physicians take newer approach in successfully treating a mysterious disease

The prognosis for the sick child, who hadn't responded to standard treatment, was dire. But a team of Rutgers physicians believed there might be hope despite the conventional wisdom against pursuing any further treatment.

27 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

Receptor News and Research

Researchers unravel how the brain chemical dopamine relates to schizophrenia

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

What makes some humans mosquito magnets?

New system to detect cancer-related markers on CTCs

What are the implications of microbial ecosystems for female reproductive health?

Does maternal obesity impact fetal brain development?

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

New insights on antibody response against SARS-CoV-2 Omiron sublineages

Study refutes the nicotinic hypothesis of SARS-CoV-2 infection mechanism

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

Ancient viral DNA in human genomes protects cells against present-day viruses

Rutgers physicians take newer approach in successfully treating a mysterious disease

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Study shows potential for eliminating surgery in a small subset of breast cancer patients

New discovery may change the textbook model of GPCR-mediated signaling

The effectiveness of BNT162b2 COVID-19 vaccine against infection with SARS-CoV-2 Omicron subvariants BA.4/5

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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