Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Old lab technique helps researchers better understand circular DNA

A 50-year-old lab technique is helping researchers better understand circular DNA, a lesser-known and poorly understood cousin of the linear version commonly associated with life's genetic blueprint.

12 Sep 2017

Two protocols help assess patients with chest pain quickly and safely in emergency departments

Two protocols for quickly and safely evaluating patients presenting to emergency departments with chest pain are being adopted by Australian hospitals.

11 Sep 2017

Gas Safety Trust conducts workshop to explore new ways for diagnosing CO poisoning

Diagnosing carbon monoxide poisoning is notoriously difficult, as it produces common, non-specific symptoms such as headaches and nausea and mimics other, more common ailments such as flu and food poisoning.

11 Sep 2017

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Pembrolizumab has shown a promising response rate in patients with pretreated metastatic gastric cancer, according to late-breaking results from the KEYNOTE-059 trial presented today at the ESMO 2017 Congress in Madrid.

8 Sep 2017

Differentiating sepsis and systemic inflammatory response syndrome using biomarkers

Firstly, it is necessary to make a distinction between systemic inflammation and Systemic Inflammatory Response Syndrome (SIRS). SIRS consists of changes in clinical signs including an abnormal body temperature, increased heart rate, increased respiratory rate, an abnormal white cell count (either decreased or elevated), or an increase in band neutrophils.

7 Sep 2017

PupilScreen could detect concussion, brain injuries on the spot using smartphone camera

University of Washington researchers are developing the first smartphone app that is capable of objectively detecting concussion and other traumatic brain injuries in the field: on the sidelines of a sports game, on a battlefield or in the home of an elderly person prone to falls.

7 Sep 2017

Breakthrough study could lead to diagnostic tools and better treatments for chronic bronchitis

When a patient arrives at a doctor's office with a persistent cough and the sensation of gunk building up in the lungs, the doctor's thought process is essentially the same as it would have been decades ago. There has been no understanding of the affected biological pathways causing the gunk buildup in the lung, nor has there been a diagnostic test for chronic bronchitis.

7 Sep 2017

Combined DNA and protein 'liquid biopsy' more accurate in identifying early-stage pancreatic cancer

Johns Hopkins scientists say they have developed a blood test that spots tumor-specific DNA and protein biomarkers for early-stage pancreatic cancer.

4 Sep 2017

Veterans affected with combat-related PTSD show changes in blood-based microRNA, study finds

Individuals affected with PTSD (Post-Traumatic Stress Disorder) demonstrate changes in microRNA (miRNA) molecules associated with gene regulation.

4 Sep 2017

Link found between fetal genes and risk of preeclampsia in mother

For the first time, a relationship has been found between fetal genes and the risk of preeclampsia in the mother.

31 Aug 2017

Rugby players take part in major study to develop ground-breaking test for concussion diagnosis

Rugby players from Aviva Premiership Rugby and Greene King IPA Championship are to take part in a major study led by the University of Birmingham as part of its work to develop a ground-breaking pitch-side test to diagnose concussion and brain injury.

30 Aug 2017

Decreasing sedentary time 21 minutes per day can help maintain muscle mass, health

Finnish researchers conducted one of the largest and longest studies to find out if it is possible to reduce sedentary time and if the reduction will result in any health benefits during one year.

30 Aug 2017

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

Parkinson's disease is an insidious disease: by the time it manifests as the typical motor dysfunctions such as tremors or muscle rigidity, portions of the brain have already been irreversibly destroyed.

29 Aug 2017

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

Is telomere length associated with the cognitive response to a lifestyle intervention? Supporting evidence from the FINGER trial.

29 Aug 2017

Anti-inflammatory therapy reduces incidence of lung cancer

In most clinical trials for cancer therapy, investigators test treatments in patients with advanced disease. But a recent cardiovascular secondary prevention study has given researchers a unique opportunity: to explore the effectiveness of giving a drug to patients before cancer emerges.

28 Aug 2017

Long non-coding RNAs could represent novel male infertility drug targets

Scientists have found distinctive portions of genetic material--known as lncRNAs--that help sperm develop. Male mice lacking a particular lncRNA have low sperm count, suggesting lncRNAs could represent novel infertility drug targets.

24 Aug 2017

Study finds ethylene release in exhaled breath as early biomarker of bacterial infection

Although ethylene (or ethene) is best known as a plant hormone, humans also produce it as consequence of oxidative stress, caused for example by the UV radiation from the sun.

24 Aug 2017

UMass Amherst chemist receives NSF funding to set up new center for autonomous chemistry

University of Massachusetts Amherst chemist Sankaran "Thai" Thayumanavan has received a three-year, $1.8 million grant from the National Science Foundation to create a multi-university Center for Autonomous Chemistry, where he and colleagues, including chemist Vince Rotello, will seek to design artificial self-activating systems, or "automatic control as nature does it," in Thayumanavan's words.

23 Aug 2017

Leading experts come together to discuss clinical, translational applications of mitochondria

The American Physiological Society will host the "Physiological Bioenergetics: Mitochondria from Bench to Bedside" conference August 27–30 in San Diego. The meeting will bring together cross-disciplinary experts who study the mitochondria, which provide the energy to individual cells.

23 Aug 2017

New technology employs machine-learning software for early detection of melanoma

New technology being developed by researchers at the University of Waterloo and the Sunnybrook Research Institute is using artificial intelligence (AI) to help detect melanoma skin cancer earlier.

23 Aug 2017

Biomarker News and Research

Further Reading

Old lab technique helps researchers better understand circular DNA

Two protocols help assess patients with chest pain quickly and safely in emergency departments

Gas Safety Trust conducts workshop to explore new ways for diagnosing CO poisoning

Study: Immunotherapy shows promising response rate in patients with metastatic gastric cancer

Differentiating sepsis and systemic inflammatory response syndrome using biomarkers

PupilScreen could detect concussion, brain injuries on the spot using smartphone camera

Breakthrough study could lead to diagnostic tools and better treatments for chronic bronchitis

Combined DNA and protein 'liquid biopsy' more accurate in identifying early-stage pancreatic cancer

Veterans affected with combat-related PTSD show changes in blood-based microRNA, study finds

Link found between fetal genes and risk of preeclampsia in mother

Rugby players take part in major study to develop ground-breaking test for concussion diagnosis

Decreasing sedentary time 21 minutes per day can help maintain muscle mass, health

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

Study: People with shorter LTL have more benefits on cognition following lifestyle intervention

Anti-inflammatory therapy reduces incidence of lung cancer

Long non-coding RNAs could represent novel male infertility drug targets

Study finds ethylene release in exhaled breath as early biomarker of bacterial infection

UMass Amherst chemist receives NSF funding to set up new center for autonomous chemistry

Leading experts come together to discuss clinical, translational applications of mitochondria

New technology employs machine-learning software for early detection of melanoma

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo