Efficacy News and Research

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Embracing nature's medicine: exploring medicinal plants for diabetes treatment

Researchers described 20 medicinal plants, their bioactive phytochemical components, therapeutic potential, modes of action, and prospects and ability to combat diabetes mellitus.

27 Jul 2023

Study provides valuable insights into the UV susceptibility of SARS-CoV-2 omicron variants

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its new variants has created a need for effective disinfection technologies to protect against harmful pathogens.

27 Jul 2023

Two infusions of IL-15-expressing CAR NK Cells boost survival in lymphoma mouse models

A new study led by researchers at The University of Texas MD Anderson Cancer Center discovered loss of metabolic fitness in chimeric antigen receptor (CAR) natural killer (NK) cells is a critical mechanism of resistance, with infused cells gradually losing the ability to compete with tumor cells for nutrients, leading to tumor relapse.

26 Jul 2023

New female contraceptive under development: end-user preferences revealed in web-based survey

Researchers investigated prospective end-user preferences for an on-demand, non-hormonal female contraception.

26 Jul 2023

Does a multidomain intervention of aerobic-resistance exercises with cognitive training and vitamin D improve cognition in older adults with mild cognitive impairment?

Researchers used a SYNERGIC Trial to evaluate the efficacy of a combination of cognitive training, progressive exercise, and vitamin D supplementation on reversing the effects of mild cognitive impairment in adults

26 Jul 2023

Heterologous booster schedules are associated with increased protection against severe, omicron related COVID-19 outcomes

Study compared different coronavirus disease 2019 (COVID-19) vaccination regimens.

26 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Study aimed to understand the specific needs of lung cancer in never smokers (LCINS) patients.

25 Jul 2023

Characterizing the concentration and binding affinity of WT–induced antibodies against the Omicron subvariant BA.1

A recent study characterized the concentration and binding affinity of antibodies induced by SARS-CoV-2 WT strain against the Omicron subvariant BA.1.

25 Jul 2023

Comparing the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste and a toothpaste with sodium fluoride

The study aimed to compare the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste and toothpaste with sodium fluoride.

25 Jul 2023

New drug delivery system may revolutionize treatment of ectopic pregnancy

Researchers in the Oregon State University College of Pharmacy have developed a drug delivery system that shows promise for greatly enhancing the efficacy of the medicine given to women with the life-threatening condition of ectopic pregnancy, which occurs when a fertilized egg implants somewhere other than the lining of the uterus.

24 Jul 2023

Arming phages with heterologous effectors paves the way for successful UTI treatment

Study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes.

24 Jul 2023

Could alpha lipoic acid treat polycystic ovary syndrome?

Authors analyzed the efficacy of alpha lipoic acid (ALA) in treating polycystic ovary syndrome (PCOS).

24 Jul 2023

Do probiotics supplements really make a difference during antibiotic treatment? Probably not, says research

Researchers evaluated previous work conducting controlled trials of patients undergoing antibiotic therapy.

24 Jul 2023

Research reveals therapeutic potential of novel compound in inhibiting oncogene translation

Cutting-edge research at the Luxembourg Institute of Health reveals the ground-breaking therapeutic potential of the compound FL3 in inhibiting oncogene translation and rewiring cancer cell metabolism, opening up new therapeutic opportunities for leukemia patients.

24 Jul 2023

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University Singapore (NTU Singapore) and Massachusetts Institute of Technology (MIT), have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics.

24 Jul 2023

Exclusion of chronic kidney disease patients from cardiovascular trials leaves significant evidence gaps

Study looks at how and where patients with CKD have been excluded from CVD RCTs over the last two decades.

24 Jul 2023

Salk researchers uncover molecular mechanisms of HIV drug resistance

Salk Institute researchers, in collaboration with the National Institutes of Health, have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV.

21 Jul 2023

Using bacteriophages to treat bladder infections

About one in two women are affected by cystitis during her lifetime, and many suffer from recurrent urinary tract infections.

21 Jul 2023

New compound shows promise in stopping breast cancer metastasis

Researchers from the University of Liverpool have created a biomedical compound that has the potential to stop the spread of breast cancer. A recently published paper details these early findings.

21 Jul 2023

Efficacy News and Research

Embracing nature's medicine: exploring medicinal plants for diabetes treatment

Study provides valuable insights into the UV susceptibility of SARS-CoV-2 omicron variants

Two infusions of IL-15-expressing CAR NK Cells boost survival in lymphoma mouse models

New female contraceptive under development: end-user preferences revealed in web-based survey

Does a multidomain intervention of aerobic-resistance exercises with cognitive training and vitamin D improve cognition in older adults with mild cognitive impairment?

Heterologous booster schedules are associated with increased protection against severe, omicron related COVID-19 outcomes

Tumor-derived GDF-15 suppresses immunotherapy response

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Characterizing the concentration and binding affinity of WT–induced antibodies against the Omicron subvariant BA.1

Comparing the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste and a toothpaste with sodium fluoride

New drug delivery system may revolutionize treatment of ectopic pregnancy

Arming phages with heterologous effectors paves the way for successful UTI treatment

Could alpha lipoic acid treat polycystic ovary syndrome?

Do probiotics supplements really make a difference during antibiotic treatment? Probably not, says research

Research reveals therapeutic potential of novel compound in inhibiting oncogene translation

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Exclusion of chronic kidney disease patients from cardiovascular trials leaves significant evidence gaps

Salk researchers uncover molecular mechanisms of HIV drug resistance

Using bacteriophages to treat bladder infections

New compound shows promise in stopping breast cancer metastasis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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