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Administration of selenide protects heart tissue post cardiac arrest, shows study

Damage to heart muscle from insufficient blood supply during cardiac arrest and reperfusion injury after blood flow is restored can be reduced by nearly 90 percent if selenide, a form of the essential nutrient selenium, is administered intravenously in the wake of the attack, according to a new preclinical study by researchers at Fred Hutchinson Cancer Research Center.

10 Apr 2015

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

You're up in the mountains, the snow is blindingly white, and the sun is blazing down from the sky: ideal skiing conditions - but any skiers carrying the herpes virus might also have to reckon with the onset of cold sores after their day out.

10 Apr 2015

Scientists identify chemical compounds that block cancer-causing oncoprotein

A team of scientists at the University of Kansas has pinpointed six chemical compounds that thwart HuR, an "oncoprotein" that binds to RNA and promotes tumor growth.

10 Apr 2015

New fluorescent probes detect problems related to lysosomes

Lysosomes are the garbage disposals of animal cells. As the resources are limited in cells, organic materials are broken down and recycled a lot -- and that's what lysosomes do.

10 Apr 2015

Researchers use new gene editing tool to cut HIV DNA

The virus that causes AIDS is an efficient and crafty retrovirus. Once HIV inserts its DNA into the genome of its host cells, it has a long incubation period, and can remain dormant and hidden for years.

10 Apr 2015

Hedione scent generates sex-specific activation patterns in brain

The question if humans can communicate via pheromones in the same way as animals is under debate. Cell physiologists at the Ruhr-Universität Bochum have demonstrated that the odorous substance Hedione activates the putative pheromone receptor VN1R1, which occurs in the human olfactory epithelium.

10 Apr 2015

Amniotic stem cells promote growth of functional blood vessels in healing hydrogels

Rice University and Texas Children's Hospital scientists are using stem cells from amniotic fluid to promote the growth of robust, functional blood vessels in healing hydrogels.

10 Apr 2015

New priority program set to develop next generation of optogenetic tools

Optogenetics is a new field of research that introduces light-sensitive proteins into cells in a genetically targeted manner, for example, to obtain information on signalling pathways and the function of neurons in a living organism.

10 Apr 2015

Research opens door to potential drug target for deadly Ebola virus

Opening the door to potential treatments for the deadly Ebola virus, scientists have found that a protein made by the virus plays a role similar to that of a coat-check attendant.

9 Apr 2015

People with high-risk tumors containing BRAF or NRAS gene mutations have lower survival rates

Researchers from the UNC Lineberger Comprehensive Cancer Center analyzed hundreds of melanoma samples to find out if two genetic mutations more commonly found in melanoma tumors were associated with lower survival rates in patients.

9 Apr 2015

BioTek to exhibit at American Association for Cancer Research 2015

BioTek Instruments will demonstrate their latest microplate-based imaging, detection and liquid handling solutions for cancer research at the AACR Annual Meeting to be held April 18-22 in Philadelphia, Pennsylvania.

9 Apr 2015

Enhanced biodiversity of worms, germs associated with better immune function, overall health

A growing body of evidence in the medical community holds that greater diversity of bacteria and even worms in the digestive tract offers protection against a variety of allergic and autoimmune problems.

9 Apr 2015

Frontier Lifeline Hospital gets approval for cardiac stem cell research by the national Apex committee for stem cell research and clinical trial (heart regeneration)

Frontier Lifeline Hospital (FLL) has been already involved in cardiac stem cell therapy post the approval by Clinical Trial registry of India, Indian Council of Medical Research (ICMR) in 2010...

9 Apr 2015

New, cross-sector collaboration aims to discover clinical biomarker for pancreatic cancer

The search to discover and validate the first-ever clinical biomarker to diagnose and treat pancreatic cancer is at the foundation of a new, cross-sector collaboration. Berg, a biopharmaceutical company committed to uncovering health solutions through a data-driven, biological research approach; the Cancer Center at Beth Israel Deaconess Medical Center, a Harvard Medical School teaching hospital, and the Pancreatic Cancer Research Team managed by Cancer Research And Biostatistics announced today they will work together to eradicate the disease.

9 Apr 2015

USPTO issues Cardio3 BioSciences Notice of Allowance for patent covering CAR-expressing TCR-deficient T-Cells

Cardio3 BioSciences, a leader in engineered cell therapies with clinical programs initially targeting indications in cardiovascular disease and oncology, today announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a significant patent application covering T-Cell receptor-deficient T-Cells which are engineered to express a chimeric antigen receptor.

9 Apr 2015

UQDI reveals that Anisina drug can kill melanoma cells

US-Australian drug discovery company, Novogen, today announced that studies conducted at The University of Queensland Diamantina Institute revealed that experimental drug, Anisina, killed melanoma cells irrespective of their mutational status.

9 Apr 2015

Study suggests that pancreatic cancers harbor genetic alterations

A genetic analysis led by UT Southwestern Medical Center researchers suggests that most pancreatic cancers harbor genetic alterations that could be targeted by existing drugs, using their genetic features as a roadmap for treatment. The findings support a precision approach to treating pancreatic cancer, the fourth most deadly cancer for both men and women.

9 Apr 2015

University of York scientists use low temperature plasmas to treat prostate cancer

Scientists at the University of York have discovered a potential new treatment for prostate cancer using low temperature plasmas (LTPs).

9 Apr 2015

UAB scientists create alternative to the use of viruses in gene therapy

A team of scientists from the Institute for Biotechnology and Biomedicine at the UAB has produced an alternative to the use of viruses in gene therapy. The researchers synthesised nanoparticles which act as artificial viruses, capable of surrounding DNA fragments and releasing them as therapeutic agents, with no biological risk, into the interior of the cells.

9 Apr 2015

Researchers link loss of WAVE1 gene to lethal form of prostate cancer

Researchers at Upstate Medical University and Harvard University have linked the loss of key gene, WAVE1, to a lethal form of prostate cancer, according to a study published in the journal Oncotarget.

9 Apr 2015

B Cell News and Research

Administration of selenide protects heart tissue post cardiac arrest, shows study

Researchers identify phenomenon that explains effects of oxidative stress on immune cells

Scientists identify chemical compounds that block cancer-causing oncoprotein

New fluorescent probes detect problems related to lysosomes

Researchers use new gene editing tool to cut HIV DNA

Hedione scent generates sex-specific activation patterns in brain

Amniotic stem cells promote growth of functional blood vessels in healing hydrogels

New priority program set to develop next generation of optogenetic tools

Research opens door to potential drug target for deadly Ebola virus

People with high-risk tumors containing BRAF or NRAS gene mutations have lower survival rates

BioTek to exhibit at American Association for Cancer Research 2015

Enhanced biodiversity of worms, germs associated with better immune function, overall health

Frontier Lifeline Hospital gets approval for cardiac stem cell research by the national Apex committee for stem cell research and clinical trial (heart regeneration)

New, cross-sector collaboration aims to discover clinical biomarker for pancreatic cancer

USPTO issues Cardio3 BioSciences Notice of Allowance for patent covering CAR-expressing TCR-deficient T-Cells

UQDI reveals that Anisina drug can kill melanoma cells

Study suggests that pancreatic cancers harbor genetic alterations

University of York scientists use low temperature plasmas to treat prostate cancer

UAB scientists create alternative to the use of viruses in gene therapy

Researchers link loss of WAVE1 gene to lethal form of prostate cancer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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