Immune System News and Research

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The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Scientists study how maternal SARS-CoV-2 infection during pregnancy affects child’s brain development

Scientists led by the Lieber Institute for Brain Development are studying how a mother's SARS-CoV-2 infection during pregnancy affects the biology of the placenta and the corresponding trajectory of the child's brain development, including the risk for neurodevelopmental disorders such as schizophrenia and autism.

13 Mar 2023

New study focuses on genetic diversity of E. coli bacteria in hospitalized patients

The human intestine is an environment inhabited by many bacteria and other microorganisms collectively known as the gut microbiome, gut microbiota or intestinal flora. In most people, it contributes to wellness.

13 Mar 2023

Simple blood test could easily pinpoint epileptic seizures

Researchers from Lund University in Sweden have discovered higher levels of immune proteins in the blood before and after an epileptic seizure.

13 Mar 2023

Abnormally low autoantibody activity significantly associated with autism severity

A recent study hypothesized a dysfunction of the self-recognition properties of the immune system in autism.

13 Mar 2023

Study creates a radical new view of how immune cells recognize threats

Researchers have created a radical new view of how immune cells recognise threats such as viruses. The discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies.

10 Mar 2023

Important backup mechanism of human immune cells elucidated

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses.

10 Mar 2023

$3 million grant supports an ambitious effort to improve children’s health around the world

An international team of researchers has received $3 million to support an ambitious effort to understand how early gut development can profoundly shape children's health throughout life.

10 Mar 2023

New discoveries made regarding autism onset in mouse models

Although autism is a common neurodevelopmental disorder, the multiple factors behind its onset are still not fully understood.

10 Mar 2023

Montana considers new wave of legislation to loosen vaccination rules

When Deb Horning's youngest daughter was 5, she got her measles, mumps, and rubella shot like many other kindergartners. But unlike many other moms, Horning had to stay away from her daughter for a week after the shot.

10 Mar 2023

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

9 Mar 2023

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Research published today shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver).

9 Mar 2023

Researchers develop a 100%-effective mRNA vaccine for deadly bacteria

For the first time in the world: a team of researchers from Tel Aviv University and the Israel Institute for Biological Research have developed an mRNA-based vaccine that is 100% effective against a type of bacteria that is lethal to humans.

9 Mar 2023

C-reactive protein has a beneficial function in systemic lupus erythematosus

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory disease.

9 Mar 2023

Microglia partner with T cells to cause neurodegeneration, study shows

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

8 Mar 2023

Study suggests a new approach for treating metastatic breast cancers

Metastatic breast cancer has no cure and has proven stubbornly resistant to one of the most innovative and promising new cancer treatments: immunotherapy.

8 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

Immune System News and Research

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Scientists study how maternal SARS-CoV-2 infection during pregnancy affects child’s brain development

New study focuses on genetic diversity of E. coli bacteria in hospitalized patients

Simple blood test could easily pinpoint epileptic seizures

Abnormally low autoantibody activity significantly associated with autism severity

Study creates a radical new view of how immune cells recognize threats

Important backup mechanism of human immune cells elucidated

$3 million grant supports an ambitious effort to improve children’s health around the world

New discoveries made regarding autism onset in mouse models

Montana considers new wave of legislation to loosen vaccination rules

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Researchers develop a 100%-effective mRNA vaccine for deadly bacteria

C-reactive protein has a beneficial function in systemic lupus erythematosus

Microglia partner with T cells to cause neurodegeneration, study shows

Study suggests a new approach for treating metastatic breast cancers

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

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