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Discovery of molecular mechanism behind spread of leishmania infection

Researchers from the Institut National de la Recherche Scientifique (INRS) have made a breakthrough in understanding the reason behind the virulence of leishmania parasite. The leishmania parasite is responsible for causing leishmaniasis which affects over 12 million people across the globe and is a chronic parasitic disease.

14 Aug 2019

Scientists demonstrate an in vitro kidney model

Kidneys work to constantly filter blood and remove toxins from the body. Conditions such as chronic kidney disease are characterized by a reduced ability to perform this essential function.

14 Aug 2019

Deadly protein combination reveals new drug targets for viral infections

New research from Cornell University details how two highly lethal viruses have greater pathogenic potential when their proteins are combined.

14 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Researchers examine how superbug fights last-resort antibiotics

Antibiotic resistance is one of the biggest threats to global health, food security, and development today. A new study shows how superbugs adapt to combat 'last-resort antibiotics'.

13 Aug 2019

Researchers make scientific breakthrough regarding Leishmania virulence strategy

A team from the Institut National de la Recherche Scientifique has made a scientific breakthrough regarding the virulence strategy employed by the Leishmania parasite to infect cells of the immune system.

12 Aug 2019

Scientists identify hereditary pancreatic cancer risk mutation

Scientists studying a highly cancer-prone family have identified a rare, inherited gene mutation that dramatically raises the lifetime risk of pancreatic and other cancers.

12 Aug 2019

Research shows that water molecules do not co-migrate via potassium channel

Do only potassium ions pass through the selectivity filter of a potassium channel, or are there water molecules between the ions? This question has been a source of controversy for years.

12 Aug 2019

Encapsulating two drugs in same nanovector can greatly improve drug delivery

Encapsulating two drugs with different properties into nanovesicles surrounded by antibodies can greatly improve their delivery and efficacy, according to a study led by Xavier Fernández Busquets, director of the joint Nanomalaria unit at the Institute for Bionengineering of Catalonia and the Barcelona Institute for Global Health, an institution supported by "la Caixa"

9 Aug 2019

Small biodegradable implant for releasing local anesthetic inside the body

Patients fitted with an orthopedic prosthetic commonly experience a period of intense pain after surgery. In an effort to control the pain, surgeons inject painkillers into the tissue during the operation.

7 Aug 2019

Blocking key mineral uptake could prevent gonorrhea infection

A team of researchers may have found a way to block gonorrhea infection by blocking bacterial pathogen from using zinc, an essential mineral found in many food sources.

6 Aug 2019

Gut cells have remarkable defense mechanism when faced with certain kinds of toxins

A team of Duke researchers has discovered that cells lining the gut of zebrafish -- and probably humans too -- have a remarkable defense mechanism when faced with certain kinds of toxins: they hit the eject button.

6 Aug 2019

FDA approves first therapy for symptomatic tenosynovial giant cell tumor

Today, the U.S. Food and Drug Administration granted approval to Turalio (pexidartinib) capsules for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations and not responsive to improvement with surgery.

3 Aug 2019

Alzheimers may be linked to genes that code formation of contacts between neurons

A team of neurobiologists from Peter the Great St. Petersburg Polytechnic University published an article on their study of the causes of Alzheimer's disease and suggested therapy methods.

2 Aug 2019

A stretchable, wireless, wearable health monitor

Researchers have developed wearable wireless monitors that contain stretchable electronics and would provide long term health data about the adults, babies and children. These sensors are an advantage over the presently used devices because they are free from the risk of skin allergic reactions and injuries that are associated with conventional adhesive sensors containing conductive gel formulations.

31 Jul 2019

New wireless, stretchable electronics for long-term health monitoring

A wireless, wearable monitor built with stretchable electronics could allow comfortable, long-term health monitoring of adults, babies and small children without concern for skin injury or allergic reactions caused by conventional adhesive sensors with conductive gels.

30 Jul 2019

Study reveals mechanism that may contribute to HIV-associated metabolic conditions

HIV-infected cells release vesicles that contain a viral protein called Nef, impairing cholesterol metabolism and triggering inflammation in uninfected bystander cells, according to a study published July 25 in the open-access journal PLOS Pathogens by Dmitri Sviridov of the Baker Heart and Diabetes Institute in Australia, and colleagues.

From PLOS ONE 26 Jul 2019

Scientists develop 3D printed pill that samples bacteria found in the gut

The gut microbiome is made up of trillions of living microbes, and more than a thousand species of bacteria. It has been known that the gut plays major roles in the body’s health. A team of university engineers may have developed a way to study and collect samples of microbes living in the gut.

25 Jul 2019

Brain protein mutation from an autistic person alters behavior in mice

A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice.

24 Jul 2019

Gene mutation in the brain of autism patients alters behaviors in mice

Autism spectrum disorder (ASD) has a wide range of possible causes, including genetics and environmental factors. Now, a new study suggests that a brain protein mutation may shed light on the mechanism of neurological and developmental illness.

23 Jul 2019