Anemia News and Research

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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.

Ruxolitinib shows promise in severe COVID-19

An anti-inflammatory drug Ruxolitinib has shown promising results in the treatment of severe coronavirus disease COVID-19. The study titled, “Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial,” was published as a pre-proof for the Journal of Allergy and Clinical Immunology.

31 May 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Common assumptions about mercury exposure should be reexamined, show studies

Small-scale gold mining in the Peruvian Amazon poses a health hazard not only to the miners and communities near where mercury is used to extract gold from ore but also to downstream communities hundreds of kilometers away from where people eat mercury-contaminated river fish as part of their diet.

29 May 2020

Clinical study shows promising results for treatment of VHL disease-associated renal tumors

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)–associated renal cell carcinoma.

28 May 2020

Researchers receive $5 million to study two types of parasitic infection

Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health totaling more than $5 million to study two types of parasitic worm infection that cause devastating illness in millions of people worldwide.

21 May 2020

Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

Study explores whether senicapoc drug can mitigate lung damage in COVID-19 patients

Scientists around the globe are working to identify approved and investigational drugs that can be repurposed to treat COVID-19.

13 May 2020

Innovative device could help treat babies with blood disorders

With severe blood disorders, such as leukemia, doctors often rely on leukapheresis, a procedure in which large machines extract whole blood from patients to separate white blood cells from the rest of the blood, which is then returned back to the patient.

8 May 2020

Impact of COVID-19 on pregnancy and breastfed infants

Pregnant women are among those at high risk of developing COVID-19, as confirmed in Wuhan early in the pandemic. A new study from Portugal published on the preprint server medRxiv in May 2020 analyses the data on the impact of COVID-19 on pregnancy and disease outcomes, using published cases of pregnant women diagnosed with the illness.

4 May 2020

Identifying high-risk groups for COVID-19 in India

A new study from the Center for Disease Dynamics, Economics and Policy sets out indicators that identify the populations at the highest risk for COVID-19 in India. The study appears on the preprint website medRxiv in April 2020.

30 Apr 2020

Iron-biofortified beans help improve physical performance of anemic women in Rwanda

Anemia is a global health problem common in low-income countries. Severe cases can lead to fatigue, heart problems, and complications in pregnancy. When widespread, anemia can also weigh on national economies.

29 Apr 2020

Novel nanoscale bio-probe could detect iron disorders

Chronic iron imbalances - having either too little or too much iron in the blood - can result in medical conditions ranging from anemia and hemochromatosis through to more severe diseases, such as cancer, Parkinson's Disease and Alzheimer's Disease.

29 Apr 2020

Study highlights the importance of malaria control in pregnant African women during COVID-19

The COVID-19 pandemic is forcing national governments around the world to take actions they never dreamed they would take.

27 Apr 2020

Talazoparib did not show overall survival benefit in patients with advanced BRCA-mutated breast cancer

New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) benefit for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

27 Apr 2020