Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Scientists decode ovarian aging with groundbreaking molecular atlas

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR signaling, and cellular communication as key to understanding fertility decline.

26 Nov 2024

Study reveals how cancer cells evade chemotherapy in low-glucose environments

Laboratory experiments with cancer cells reveal two ways in which tumors evade drugs designed to starve and kill them, a new study shows.

26 Nov 2024

New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

How alcohol impacts male health

This research explores how alcohol consumption disrupts metabolism, damages the liver, and impairs male reproductive health, emphasizing the complex mechanisms and public health implications.

18 Nov 2024

Phase 2 study evaluates safety and efficacy of asunercept in COVID-19 patients

The ASUNCTIS trial evaluated asunercept's safety and efficacy in COVID-19, showing trends toward faster recovery despite not meeting statistical significance.

18 Nov 2024

Spermidine regulates RIPK1 to combat diabetes and vascular damage

Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, offering potential therapeutic strategies for type 2 diabetes.

18 Nov 2024

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Researchers review the biological activities of growth hormone-releasing hormone and its analogs.

17 Nov 2024

Vitamin D receptor activation slows cell overgrowth in pulmonary hypertension

The study demonstrates that activating the vitamin D receptor (VDR) with calcitriol suppresses cell proliferation in pulmonary arterial smooth muscle cells, potentially reducing disease severity in pulmonary arterial hypertension (PAH).

12 Nov 2024

Exploring the anticancer potential of medicinal plants

Cancer remains one of the leading global causes of mortality, with an estimated increase in cases due to lifestyle, environmental, and genetic factors.

8 Nov 2024

Berry-flavored vapes impair lung immune response

Alterations in AM function following the exposure to berry-flavored e-cigarettes that lead to poor immune responses to pathogens and reduced host survival.

7 Nov 2024

Epigenetic silencing of BEND4 unveils new path for PDAC treatment

A novel discovery in the field of pancreatic cancer treatment has been unveiled, revealing the epigenetic silencing of BEND4 as a potential synthetic lethal marker for enhancing the efficacy of ATM inhibitors in pancreatic cancer treatment.

7 Nov 2024

A novel synthetic lethal target for ATM inhibitors in pancreatic cancer

5 Nov 2024

Machine learning identifies key genes linking rheumatoid arthritis and osteoporosis

Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the joints and can result in pain, swelling, and damage to the cartilage and bone.

5 Nov 2024

Modulating CD39 expression to enhance CAR-T cell therapy against hepatocellular carcinoma

In the quest to enhance the efficacy of chimeric antigen receptor T (CAR-T) cell therapy against hepatocellular carcinoma (HCC), a recent study has identified a pivotal role for CD39 expression in modulating the function of CAR-T cells.

5 Nov 2024

Study identifies six cancer susceptibility genes

Identification of six cancer susceptibility genes offers new insights into genetic risk factors, potentially enhancing early detection and treatment strategies.

29 Oct 2024

Unraveling the mystery of cancer resistance

Every multicellular creature - whether soaring through the skies, swimming in the ocean's depths or roaming the earth's surface - shares a common vulnerability: the uncontrolled growth of cells known as cancer.

29 Oct 2024

Extracellular vesicles play key role in cancer drug resistance

Despite significant advancements in cancer treatment, drug resistance remains a persistent challenge. Cancer cells can often develop resistance to treatments such as chemotherapy, radiotherapy, and immunotherapy, leading to reduced treatment efficacy.

25 Oct 2024