Sedative News and Research

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A sedative is a substance that induces sedation by reducing irritability or excitement.

In the ICU, use of benzodiazepines, other factors may predict severity of post-stay depression

Psychiatrists and critical care specialists at Johns Hopkins have begun to tease out what there is about a stay in an intensive care unit (ICU) that leads so many patients to report depression after they go home.

12 Apr 2009

CyDex Pharmaceuticals taste-masking formulation patent and patent application up for sale

IpAuctions, Inc. will auction one pharmaceutical patent and one patent application on behalf of specialty pharmaceutical company CyDex Pharmaceuticals, Inc. of Lenexa, Kansas, USA.

6 Apr 2009

Link between sleeping medicine use and driving impairment

A new study from the Norwegian Institute of Public Health shows a positive link between the amount of the hypnotic (sleeping medicine) zopiclone in the blood and the chance of being assessed as impaired in a clinical examination.

29 Mar 2009

Low to moderate drinking releases 'feel-good' endorphins in the brain, not heavy drinking

Scientists know that alcohol affects the brain, but the specifics remain unclear.

20 Mar 2009

Happy pills in America -- Our complex love affair with designer consciousness

The spectacular increase in the use of psychiatric drugs over the past 50 years involved what a University at Buffalo historian calls "a massive break with what we consider 'normal' mental health," one linked to myriad social and cultural changes in America.

19 Mar 2009

University at Buffalo designed ventilator can safely sedate ICU patients for less

A new, recently licensed medical device developed by University at Buffalo researchers would introduce into intensive care settings the powerful and effective method of anesthetizing patients that works so well in the operating room.

25 Feb 2009

New approach to dental visits may ease kids' fears

For many children, a trip to the doctor or dentist is a stressful experience.

22 Feb 2009

Sedative dexmedetomidine may offer advantages over agents often used for sedation in ICU

Use of the sedative dexmedetomidine for critically ill patients resulted in less time on a ventilator and less delirium compared to patients administered a more commonly used drug, according to a study in the February 4 issue of JAMA, the Journal of the American Medical Association.

2 Feb 2009

Anxious seniors may benefit from SSRIs

Many older adults worry - a lot. Almost one in 10 Americans over age 60 suffer from an anxiety disorder that causes them to worry excessively about normal things - like health, finances, disability and family.

21 Jan 2009

FDA approves Lusedra (fospropofol disodium) injection for monitored anesthesia care sedation

Eisai Corporation of North America today announced that the U.S. Food and Drug Administration (FDA) has approved Lusedra (fospropofol disodium) Injection, an intravenous sedative-hypnotic agent for monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures.

14 Dec 2008

Numbing drugs can have profound and long-term negative effects

A large proteomics study on the brains of newborn mice provides more evidence that numbing drugs often used in obstetric or pediatric medicine can have profound and long-term negative effects, even after minimal exposure.

12 Dec 2008

Controlling the building blocks of life

A simple and reliable method for converting one of the simplest chemical entities into one of the most difficult-to-make molecular building blocks of life, with complete control over its shape, is reported by scientists at the University of Bristol in this week's Nature.

10 Dec 2008

New sleeping pill could be the answer to jet lag

An experimental drug developed by Australian scientists could offer a new cure for jet lag and be a welcome alternative to addictive sedatives such as benzodiazepines.

3 Dec 2008

FDA approves tapentadol immediate-release tablets for pain in adults

Millions of Americans with moderate to severe acute pain and their health-care providers will soon have a new treatment option.

21 Nov 2008

Sedative propofol could be fatal

Patients treated for their prolonged seizures with the sedative propofol may be at high risk for complications and even death. New research presented at CHEST 2008, the 74th annual international scientific assembly of the American College of Chest Physicians (ACCP), shows that the use of propofol as an antiepileptic agent in patients with refractory status epilepticus (RSE), prolonged seizures that do not respond to initial treatment, was associated with significant mortality and morbidity.

28 Oct 2008

New kinds of optical sensors make MRI scans safer

Magnetic resonance scans will be safer for children and other patients needing anaesthesia, thanks to new kinds of optical sensors developed by a team of European researchers.

21 Sep 2008

Watson Pharmaceuticals launches generic version of dronabinol

Watson Pharmaceuticals, Inc. has announced that, under a supply agreement with Solvay Pharmaceuticals, Inc., Watson has launched the authorized generic version of dronabinol in the 2.5, 5 and 10 mg once daily dosage strengths.

30 Jun 2008

Drinking patterns in adolescents may be set after only a few exposures to alcohol

Scientists at Duke University Medical Center have shown a connection between early drinking patterns and a tendency to be a heavy drinker in adulthood, in a study of adolescent rats.

5 May 2008

Children's experiences in a pediatric intensive care unit

Nearly one in three children admitted to pediatric intensive care will experience delusions or hallucinations, which put them at higher risk for post-traumatic stress symptoms, according to a new study of children's experiences in a pediatric intensive care unit (PICU).

1 May 2008

Competency in colonoscopy requires experience with 150 cases or more

Researchers from Korea have found that technically efficient screening and diagnostic colonoscopy generally requires experience with 150 cases or more.

23 Apr 2008