White Blood Cell News and Research

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Beta-blockers show anti-inflammatory effects in cirrhosis

Approximately 170,000 people die every year in Europe from the direct consequences of advanced chronic liver disease (cirrhosis).

10 Dec 2020

New guidelines improved the ability to predict C. diff infection mortality

Clostridioides difficile infection (CDI) is the most common health care-associated infection in the United States, causing an estimated 12,800 deaths each year.

9 Dec 2020

Study compares effects of two omega-3s in older adults with obesity and chronic inflammation

The omega-3 fatty acids EPA and DHA work differently against chronic inflammation, according to the results of a small randomized study, suggesting each has its own important role to play in regulating the immune system.

8 Dec 2020

Higher degrees of necrosis are inked to poor survival in brain cancer patients

White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die – but that's not good news, according to researchers at Penn State College of Medicine and Penn State Cancer Institute.

8 Dec 2020

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.

7 Dec 2020

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

Psoriasis has always been a common disease. Historically, its causes were obscure and surrounded by stigma; it wasn't until recently that scientists categorized it as an autoimmune condition.

4 Dec 2020

A new potential COVID-19 vaccine candidate: YF-S0

A recent study published in the journal Nature describes the safety and efficacy of a live-attenuated yellow fever 17D (YF17D) vector-based vaccine candidate expressing a non-cleavable form of the spike protein of severe acute respiratory coronavirus 2 (SARS-CoV2).

2 Dec 2020

How COVID-19 compares to other respiratory illnesses

A team of scientists from Israel and the United States has compared the disease presentation and progression between in-hospital patients with coronavirus disease 2019 (COVID-19) and other respiratory illnesses such as influenza.

23 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Tohoku University scientists have found that human editing enzymes are likely behind a type of mutation in the COVID-19 virus that stimulates the release of pro-inflammatory molecules called cytokines by immune cells in the body.

11 Nov 2020

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Recently, researchers from The Johns Hopkins University School of Medicine, Baltimore, MD, USA, and Capricor Therapeutics, Inc., Beverly Hills, CA, USA, described a new approach to SARS-CoV-2 vaccine development using exosomes to deliver mRNAs that encode the antigens from multiple structural proteins of the virus.

9 Nov 2020

Delirium common after hospital discharge in critically ill COVID-19 patients

Anesthesiologist and other researchers from Michigan Medicine, Ann Arbor, New York Medical College, Valhalla and Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, have reported a case series of critically ill coronavirus disease 2019 (COVID-19) patients who have developed neuropsychological symptoms after having been discharged from the hospital.

8 Nov 2020

TB screening needed for people on methotrexate who live in at-risk areas

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that tuberculosis (TB) screening and ongoing clinical care is needed for people on methotrexate who live in areas where the highly infectious illness is common.

6 Nov 2020

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

As the treatment of severe COVID-19 is very difficult, the researchers from the Korea Research Institute of Biosciences and Biotechnology (KRIBB) suggested that DNase-1 can be utilized to dissolve the neutrophil extracellular traps (NETs), hence halting the further progression of COVID-19.

27 Oct 2020

COVID-19 patient's immune response may underlie the effects on the nervous system

It is probably the immune response to, rather than the virus in itself, that causes sudden confusion and other symptoms from the nervous system in some patients with COVID-19. This is shown by a study of cases involving six Swedish patients, now published in the journal Neurology.

22 Oct 2020

NIH awards $1.6 million for research on hormonal control of HIV latency

The National Institutes of Health has awarded $1.6 million to researchers at the George Washington University School of Medicine and Health Sciences for research on hormonal control of HIV latency.

20 Oct 2020

The connection between severe COVID-19 and white blood cell counts

However, in other research, white blood cells' exact roles and subtypes in severe COVID-19 are still unclear. The team writes, "It is unknown if blood cell counts before infection are associated with the risk of developing severe COVID-19." They explained that the numbers of these cell types could be influenced by several factors such as age, gender, disease status, and medications.

19 Oct 2020

White Blood Cell News and Research

Beta-blockers show anti-inflammatory effects in cirrhosis

New guidelines improved the ability to predict C. diff infection mortality

Study compares effects of two omega-3s in older adults with obesity and chronic inflammation

Higher degrees of necrosis are inked to poor survival in brain cancer patients

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

A new potential COVID-19 vaccine candidate: YF-S0

How COVID-19 compares to other respiratory illnesses

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Uracil point mutations found in SARS-CoV-2 variants alter innate immune responses

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Delirium common after hospital discharge in critically ill COVID-19 patients

TB screening needed for people on methotrexate who live in at-risk areas

DNase coated melanin-like nanospheres for sepsis treatment in severe COVID

COVID-19 patient's immune response may underlie the effects on the nervous system

NIH awards $1.6 million for research on hormonal control of HIV latency

The connection between severe COVID-19 and white blood cell counts

Temple researchers identify criteria to predict cytokine storm in COVID-19 patients

Higher levels of lymphocytes reduce risk of long-term complications in asymptomatic COVID-19 patients

Understanding the production of memory B cells and immune responses

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