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Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

A recent study investigates poorer vaccine responses observed in the elderly following receipt of a COVID-19 booster vaccination dose.

19 Oct 2022

Licorice root extract shows potential as a COVID-19 treatment

A recent study explores the activity of glycyrrhizin against SARS-CoV-2.

19 Oct 2022

Immune-suppressing drug reverses symptoms of delirium in mice

Investigators from the departments of Neurology, Neurosurgery, Psychiatry, Medicine, and Biomedical Sciences at Cedars-Sinai have shown that an immune-suppressing drug similar to one used to treat severe COVID-19 reversed symptoms of delirium in mice whose lungs were injured during mechanical breathing assistance.

19 Oct 2022

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

According to a recent study, substance P produced by the nociceptors present in the gut lining confers protection against inflammation and tissue damage by increasing the number of beneficial microbes.

19 Oct 2022

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.

19 Oct 2022

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).

19 Oct 2022

Adaptation-proof SARS-CoV-2 vaccine design is one step closer to reality

A vaccine design approach that could protect against new variants of SARS-CoV-2, the virus that causes COVID-19, but also potentially protects against other coronaviruses is one step closer to reality as a result of Penn State College of Medicine research.

18 Oct 2022

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

A pseudovirus system based on deep mutational scanning determines how SARS-CoV-2 mutations can affect its ability to escape neutralization.

18 Oct 2022

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

During brain development, neurons have to migrate long distances through complex environments until they reach their final destination.

18 Oct 2022

Does skin inflammation exacerbate COVID-19?

In a new study, researchers discussed inflammation during infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Oct 2022

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

A new study evaluated the current research on incidences of hypertension, new-onset diabetes mellitus, and dyslipidemia as possible sequelae of coronavirus disease 2019 (COVID-19).

18 Oct 2022

What is the function of micronutrients in COVID-19 recovery?

Researchers assessed the function of micronutrients and metabolites derived from gut microbiota in coronavirus disease 2019 (COVID-19) recovery.

18 Oct 2022

Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to the bioRxiv* preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.

18 Oct 2022

Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

High immune protein levels predict both heart failure and death

For years, cardiologists have zeroed in on a hormone called BNP as a gold standard to determine if patients with heart failure are at risk of severe illness or death. It's released by the heart in response to when the cardiac tissue stretches due to pressure.

17 Oct 2022

Novel drug target for triple-negative breast cancer discovered

Research led by Dr. Suresh Alahari, Professor of Biochemistry at LSU Health New Orleans' Schools of Medicine and Graduate Studies, reports a combination of a novel small inhibitory molecule and an FDA-approved chemotherapy drug suppresses the growth of triple-negative breast cancer cells synergistically.

17 Oct 2022

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

In a new study, researchers determined plasma signatures of proteins related to or derived from platelets in acute isolated pulmonary embolism (iPE) and deep vein thrombosis-associated PE (DVT-PE), compared to isolated DVT (iDVT).

17 Oct 2022

Owner SARS-CoV-2 RNA load shown to be associated with infection in pet dogs

A new study assessed the potential association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) load in owners with SARS-CoV-2 infection in their dogs.

17 Oct 2022

Study of the clinico-demographic features, clinical history, and virological markers to predict COVID-19 progression in hospitalized adults

Researchers studied the characteristics and markers associated with COVID-19 disease progression in hospitalized adults.

17 Oct 2022

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Scientists identified five hub genes that might be associated with severe COVID-19 outcomes in patients with diabetic kidney disease.

17 Oct 2022

Receptor News and Research

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

Licorice root extract shows potential as a COVID-19 treatment

Immune-suppressing drug reverses symptoms of delirium in mice

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Adaptation-proof SARS-CoV-2 vaccine design is one step closer to reality

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

Unc5-GPC3 complex modulates the migration of neurons and brain-derived cancer cells

Does skin inflammation exacerbate COVID-19?

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

What is the function of micronutrients in COVID-19 recovery?

Bioinformatics analysis of monkeypox virus-host cell interactions

Study explores the effect of COVID-19 on platelet function

High immune protein levels predict both heart failure and death

Novel drug target for triple-negative breast cancer discovered

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

Owner SARS-CoV-2 RNA load shown to be associated with infection in pet dogs

Study of the clinico-demographic features, clinical history, and virological markers to predict COVID-19 progression in hospitalized adults

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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