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Study reveals best treatment strategy for high-risk pulmonary embolism

A current study involving the University Hospital Bonn (UKB) has investigated which treatment strategy offers the best chances of survival in high-risk acute pulmonary embolism.

4 Mar 2025

This International Women’s Day, Meet the Scientist Changing Women’s Health

Prof. Dr. Inge Herrmann discusses her innovative work in healthcare, focusing on a reversible hydrogel implant that could transform gynecological treatments.

4 Mar 2025

Breakthrough study sheds light on Pol-theta’s role in DNA repair and cancer

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these proteins-called polymerase theta (Pol-theta)-for their own survival.

4 Mar 2025

Stem cell therapy for cornea injuries demonstrates remarkable results in clinical trial

An expanded clinical trial that tested a groundbreaking, experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients who were treated and followed for 18 months, and there was a high proportion of complete or partial success.

4 Mar 2025

Targeting mitochondrial DNA integrity for cardiac protection after injury

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury.

4 Mar 2025

Alpha particle therapy offers new hope for neuroendocrine tumors

In a comprehensive Genomic Press Viewpoint (review) article, researchers are shining a spotlight on a revolutionary approach to tackling neuroendocrine tumors (NETs), a rare but increasingly prevalent form of cancer.

4 Mar 2025

UQ clinical study seeks participants with PTSD and complex PTSD

University of Queensland researchers are seeking participants diagnosed with PTSD and complex PTSD for a clinical study aimed at improving understanding of its impacts on the brain and overall well-being.

3 Mar 2025

Synthetic microbiome therapy offers new hope against C. difficile infections

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

3 Mar 2025

Study elucidates mechanism behind bacterial cancer therapy

A research team led by Prof. Liu Chenli from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences (CAS) and Prof. Xiao Yichuan from the Shanghai Institute of Nutrition and Health of CAS elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.

3 Mar 2025

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence base supporting the idea that it can improve brain health-in humans as well as animals-has emerged from the work of labs all over the world.

3 Mar 2025

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Talk therapy delivered by non-specialists effective for pregnant and postpartum individuals

Approximately one in five of pregnant and postpartum individuals experience depression and anxiety, yet less than 10 per cent receive proper treatment.

3 Mar 2025

Hallucinogen use linked to increased risk of mortality in emergency care patients

People seeking emergency care for hallucinogen use were at 2.6-fold higher risk of death within 5 years than the general population, according to a new study published in CMAJ.

3 Mar 2025

Co-occurring mutations may limit effectiveness of KRAS G12C inhibitors in colorectal and pancreatic cancer

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C inhibitors, despite no prior treatment with this therapy, according to recent results from a large multidatabase analysis.

3 Mar 2025

Targeting SSAT enzyme offers new hope for psoriasis treatment

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting around 250,000 people in Austria.

3 Mar 2025

Medtronic receives FDA approval for BrainSense Adaptive DBS technology

For the one million people diagnosed with Parkinson's disease in the United States, Medtronic plc (NYSE:MDT), a global leader in healthcare technology, proudly announces U.S. Food and Drug Administration (FDA) approval of BrainSense™ Adaptive deep brain stimulation (aDBS) and BrainSense™ Electrode Identifier (EI).

3 Mar 2025

Pioneering the world’s first CRISPR medicine for sickle cell disease

When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes.

3 Mar 2025

Omalizumab outperforms oral immunotherapy in treating multi-food allergy

A clinical trial has found that the medication omalizumab, marketed as Xolair, treated multi-food allergy more effectively than oral immunotherapy (OIT) in people with allergic reactions to very small amounts of common food allergens.

2 Mar 2025

St. Jude scientists discover how retinoic acid selectively kills metastatic neuroblastoma cells

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10-15%.

2 Mar 2025

Understanding the benefits and risks of hyperbaric oxygen therapy

Hyperbaric oxygen therapy is well known for treating scuba and deep-sea divers affected by the rapid change in pressure around them. But did you know that HBOT is also used to treat a variety of other health problems, including carbon monoxide poisoning and diabetic foot ulcers?

28 Feb 2025