Clinical Trial News and Research

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Researchers take an important step forward in treating combat-related post-traumatic stress disorder

Study findings out today in JAMA Network Open show an important step forward in treating the psychological injuries of war.

5 Jan 2023

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells in and around a tumor, called tumor-infiltrating lymphocytes (TILs), in predicting whether HER2-positive breast cancer responds to treatment.

5 Jan 2023

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Insilico Medicine, a clinical stage, end-to-end artificial intelligence (AI)-driven drug discovery company, held the launch ceremony for Life Star – a 6th generation Intelligent Robotics Drug Discovery Laboratory – in Suzhou BioBAY Industrial Park on Dec. 29.

5 Jan 2023

Acupuncture could be a safe and feasible management option for IBS-D

Researchers preliminarily evaluated the practicality of utilizing the United States (US) Food and Drug Administration (FDA)-advocated endpoints to assess the effectiveness of acupuncture in IBS-D (irritable bowel syndrome with diarrhea) management.

5 Jan 2023

Study assesses microbiome of male genital mucosa

A new study in the journal Microorganisms aimed to identify and analyze studies on the composition of the microbial community on different parts of the healthy and diseased male genital mucosa.

4 Jan 2023

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.

4 Jan 2023

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Newly published research out of the University of Cincinnati and the University of California-Davis shows that direct oral anticoagulant (DOAC) drugs are more effective and are more cost-effective than low molecular weight heparin for treating cancer-associated thrombosis.

4 Jan 2023

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

Researchers conducted a literature review to determine whether platelet-rich plasma therapy could help slow disease progression through lung regeneration in patients with chronic respiratory disease.

4 Jan 2023

RQM+ Launches Clinical Trial Services

RQM+ today announced the launch of its clinical trial services division to complete its full complement of MedTech contract research organization (CRO) services.

From RQM+ 4 Jan 2023

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with poor prognosis and limited treatment options.

3 Jan 2023

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

A clinical trial led by the National Cancer Institute (NCI), part of the National Institutes of Health, has resulted in the first approval of a treatment for advanced alveolar soft part sarcoma (ASPS).

28 Dec 2022

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer's disease neurodegeneration in a blood sample. A study on their results was published today in Brain.

28 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Study compares two non-invasive interventions for spine pain on disability and health care spending

Pain in the back or the neck is extremely common and accounts for more healthcare spending than any other health condition.

23 Dec 2022

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

22 Dec 2022

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia.

22 Dec 2022

Partial knee arthroplasty yields faster functional recovery than total knee replacement

For selected patients with knee osteoarthritis, unicompartmental (or "partial") knee arthroplasty (UKA) shortens the recovery time for two key measures of physical function, as compared with total knee arthroplasty (TKA), reports a randomized trial in The Journal of Bone & Joint Surgery.

22 Dec 2022

UK government strikes a deal with Moderna to boost mRNA research and development

Patients in the UK will be protected against potential future global health threats, including potential pandemics, thanks to a deal struck between the government and Moderna.

22 Dec 2022

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

21 Dec 2022

Clinical Trial News and Research

Researchers take an important step forward in treating combat-related post-traumatic stress disorder

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Acupuncture could be a safe and feasible management option for IBS-D

Study assesses microbiome of male genital mucosa

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

RQM+ Launches Clinical Trial Services

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Study compares two non-invasive interventions for spine pain on disability and health care spending

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

Partial knee arthroplasty yields faster functional recovery than total knee replacement

UK government strikes a deal with Moderna to boost mRNA research and development

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

eBook: Using iPSCs models for human disease research and drug discovery eBook

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