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ViiV Healthcare presents positive results from LATTE-2 study at CROI

ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer Inc. and Shionogi Limited as shareholders, today presented positive results from the LATTE-2 study at the Conference on Retroviruses and Opportunistic Infections (CROI) in Boston. Headline results were announced in November 2015.

24 Feb 2016

ARV drug atazanavir may have significant effects on infant development

The antiretroviral (ARV) drug atazanavir—sometimes included in treatments to prevent mother-to-child HIV transmission during pregnancy—may have small but significant effects on infant development, reports a study in the journal AIDS, official journal of the International AIDS Society.

23 Feb 2016

Dapivirine ring can help prevent HIV-1 infection in women

In an important scientific achievement for women's health, two large Phase III clinical trials -- The Ring Study and ASPIRE -- have shown that a monthly vaginal ring containing the antiretroviral drug (ARV) dapivirine can safely help prevent HIV-1 infection in women.

23 Feb 2016

Researchers develop designer recombinase that can remove provirus from HIV-1 isolates

Researchers at the Medical Faculty of the Technische Universität Dresden and the Heinrich Pette Institute, Leibniz Institute for Experimental Virology succeeded in developing a designer recombinase (Brec1) that is capable of specifically removing the provirus from infected cells of most primary HIV-1 isolates.

23 Feb 2016

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Namandje Bumpus, Ph.D., and Jordan Green, Ph.D., of the Johns Hopkins University School of Medicine are among 105 winners of Presidential Early Career Awards for Scientists and Engineers, which were announced by the White House on Feb. 18.

23 Feb 2016

Study identifies new mechanism for controlling HIV replication

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus.

23 Feb 2016

Researchers identify new group of powerful Ebola-fighting antibodies

A research team that included scientists from The Scripps Research Institute has identified a new group of powerful antibodies to fight Ebola virus.

22 Feb 2016

Zika virus can cross the placental barrier, according to new study

A study of pregnant women in Brazil has confirmed the presence of Zika virus in the amniotic fluid of two women who had displayed Zika-like symptoms during their pregnancies.

18 Feb 2016

Study demonstrating link between anal cancer and HPV infection published in Obstetrics & Gynecology

Researchers at Women & Infants Hospital, a Care New England hospital, recently published the results of a study demonstrating a connection between anal cancer and human papillomavirus (HPV) infection.

18 Feb 2016

Discovery could lead to more effective vaccines, personalised therapies for TB

Tuberculosis (TB) used to kill one in seven people around the world before the advent of antibiotics. However the increasing prevalence of multi-drug resistant TB means that doctors are running out of options in trying to combat this bacterium.

18 Feb 2016

WRAIR begins Phase 1 clinical trial to evaluate MERS vaccine candidate

The Walter Reed Army Institute of Research began vaccinations today in a Phase 1 clinical trial to evaluate the safety and immune response of a vaccine candidate to prevent Middle East Respiratory Syndrome (MERS).

17 Feb 2016

Transgender people serving in US military report few mental, physical health problems

A new study shows that transgender active-duty U.S. military personnel report few lifetime mental and physical health problems.

17 Feb 2016

Researchers identify how Toxoplasma parasite crosses blood-brain barrier

An estimated 30 percent of the world's population is chronically infected with the parasite Toxoplasma gondii. Most people live with the infection without noticeable effect, but it can be life-threatening for people with suppressed immune systems, such as people on cancer therapies or who have HIV/AIDS.

16 Feb 2016

Implementing harm reduction interventions among PWID to prevent HIV epidemic in Colombia

In the early 1990s, drug production in Colombia diversified to include heroin as well as cocaine, and since then the country's role in the heroin trade has substantially increased. According to the United Nations Office on Drugs and Crime, Colombia produced approximately 70 to 100 metric tons of heroin between 1998 and 2004. Studies have found an increase in local heroin use since the mid-1990s. This is a strong cause for concern, given the potential for HIV to spread through networks of injection drug users and disseminate to the general public.

15 Feb 2016

Leeds scientists to start computer drug research to find cure for Ebola virus

Scientists at the University of Leeds will run the equivalent of password cracking software to find the chemical keys to defeating the Ebola virus.

11 Feb 2016

UW-Madison research team starts work on Zika virus infection

In October, when David O'Connor last visited Brazil as part of a decade-long research program studying drug-resistant strains of HIV, one of his Brazilian collaborators had a request.

11 Feb 2016

Johns Hopkins becomes first center in the U.S. to perform HIV-positive to HIV-positive organ transplants

Johns Hopkins recently received approval from the United Network for Organ Sharing to be the first hospital in the U.S. to perform HIV-positive to HIV-positive organ transplants. The institution will be the first in the nation to do an HIV-positive to HIV-positive kidney transplant and the first in the world to execute an HIV-positive to HIV-positive liver transplant.

11 Feb 2016

TSRI scientists develop new screening device for drug discovery

Screening large "libraries" of compounds to find those with a desired biological activity is a powerful method for discovering new drugs, but requires a large, expensive and dedicated facility. Now, scientists at the Florida campus of The Scripps Research Institute have devised the central component of a screening system that would be orders of magnitude smaller and cheaper.

11 Feb 2016

Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers have been named winners of the 2016 Elsevier Foundation Awards for Early Career Women Scientists in the Developing World, in recognition of research that has strong potential health and economic benefits.

10 Feb 2016

Hormone therapy may improve psychological functioning in transgender individuals

Transgender individuals may experience significant improvement in psychological functioning after as little as 3-6 months of hormone therapy, with improved quality of life reported within 12 months of initiating therapy by both female-to-male and male-to-female transgender individuals, according to an article published in Transgender Health, a new peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers.

10 Feb 2016

HIV 1 News and Research

ViiV Healthcare presents positive results from LATTE-2 study at CROI

ARV drug atazanavir may have significant effects on infant development

Dapivirine ring can help prevent HIV-1 infection in women

Researchers develop designer recombinase that can remove provirus from HIV-1 isolates

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Study identifies new mechanism for controlling HIV replication

Researchers identify new group of powerful Ebola-fighting antibodies

Zika virus can cross the placental barrier, according to new study

Study demonstrating link between anal cancer and HPV infection published in Obstetrics & Gynecology

Discovery could lead to more effective vaccines, personalised therapies for TB

WRAIR begins Phase 1 clinical trial to evaluate MERS vaccine candidate

Transgender people serving in US military report few mental, physical health problems

Researchers identify how Toxoplasma parasite crosses blood-brain barrier

Implementing harm reduction interventions among PWID to prevent HIV epidemic in Colombia

Leeds scientists to start computer drug research to find cure for Ebola virus

UW-Madison research team starts work on Zika virus infection

Johns Hopkins becomes first center in the U.S. to perform HIV-positive to HIV-positive organ transplants

TSRI scientists develop new screening device for drug discovery

Five researchers named winners of 2016 Elsevier Foundation Awards

Hormone therapy may improve psychological functioning in transgender individuals

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