Clinical Trial News and Research

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Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19.

27 Oct 2022

UC San Diego participates in national trial to assess potential treatment for human monkeypox

The University of California San Diego will be one of multiple sites assessing the safety and efficacy of tecovirimat as a potential treatment for human monkeypox.

27 Oct 2022

Study shows potential for eliminating surgery in a small subset of breast cancer patients

Researchers evaluate the efficacy of radiotherapy in patients with early-stage HER2-positive breast cancer or TNBC after neoadjuvant systemic therapy.

27 Oct 2022

Low-carb diet may be a useful approach for preventing and treating Type 2 diabetes

While low-carb diets are often recommended for those being treated for diabetes, little evidence exists on whether eating fewer carbs can impact the blood sugar of those with diabetes or prediabetes who aren't treated by medications.

26 Oct 2022

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

In this interview, Dr. Shebna Massey discusses neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and more. She also discusses and explores new therapeutic targets and biomarkers for these diseases.

From Sino Biological Inc. 26 Oct 2022

Study finds new drug combination to be more effective against complicated urinary tract infections

An international study led by a Rutgers scientist comparing new and older treatments against complicated urinary tract infections has found a new drug combination to be more effective, especially against stubborn, drug-resistant infections.

25 Oct 2022

New evidence on how intermittent fasting impacts women's reproductive hormones

Intermittent fasting has been shown to be an effective way to lose weight, but critics have worried that the practice may have a negative impact on women's reproductive hormones.

25 Oct 2022

Study offers a combination treatment option for patients with oligometastatic prostate cancer

A new study offers a new option to patients with oligometastatic prostate cancer who want relief from hormone therapy without compromising the risk of their disease spreading.

25 Oct 2022

Interrupting prolonged sitting with periodic activity "snacks" may help maintain muscle mass, study says

Interrupting prolonged sitting with periodic activity "snacks" may help maintain muscle mass and quality, according to a new study by researchers at the University of Toronto.

25 Oct 2022

Researchers streamline way to manufacture CAR T-cells in just 24 hours

Researchers at University Hospitals (UH) Seidman Cancer Center and a biotech start-up company have developed a streamlined way to manufacture CAR T-cells for immunotherapy treatment in just 24 hours – an improvement over the team's previous benchmark of eight days and commercial suppliers that typically take three weeks.

25 Oct 2022

More intensive prostate cancer screening may reduce the risk of metastatic cancer later

In the face of conflicting evidence over the risks and benefits of routine prostate cancer screenings, a large, longitudinal analysis found Veterans Health Administration medical centers with lower prostate screening rates had higher rates of metastatic prostate cancer cases in subsequent years than centers with higher screening rates.

24 Oct 2022

Meeting with a medical physicist reduces patients' radiation treatment-related stress

Meeting with a medical physicist who can explain how radiation therapy is planned and delivered reduces patient anxiety and increases patient satisfaction throughout the treatment process, according to a new study published today in the International Journal of Radiation Oncology • Biology • Physics.

24 Oct 2022

Combination of radiation and systemic therapy can prolong survival for advanced liver cancer patients

Adding radiation therapy to systemic therapy for patients with advanced liver cancer can extend overall survival and delay tumor progression without compromising patients' quality of life, a randomized phase III clinical trial shows.

24 Oct 2022

Clinical trial confirms the safety, efficacy of shortened radiation therapy for high-risk prostate cancer patients

A new randomized study confirms that men with high-risk prostate cancer can be treated with five versus eight weeks of radiation therapy.

24 Oct 2022

FLASH radiotherapy may hold promise as a potential treatment for tough-to-kill tumors

FLASH radiation treatment – which delivers therapeutic doses of radiation in a fraction of a second – may hold promise as a potential treatment for tough-to-kill tumors, a first-in-human study in a small number of people with bone cancer suggests.

24 Oct 2022

Treating high-risk, asymptomatic bone metastases with radiation may reduce pain, extend survival

Treating high-risk, asymptomatic bone metastases with radiation may reduce painful complications and hospitalizations and possibly extend overall survival in people whose cancer has spread to multiple sites, a phase II clinical trial suggests.

24 Oct 2022

Duke biomedical engineers develop a two-pronged approach to treating pancreatic cancer

Biomedical engineers at Duke University have demonstrated the most effective treatment for pancreatic cancer ever recorded in mouse models.

21 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Three-dose course of the hepatitis B vaccine fully protects adults living with HIV

A three-dose course of the hepatitis B vaccine HEPLISAV-B fully protected adults living with HIV who had never been vaccinated against or infected with the hepatitis B virus (HBV), according to study findings presented today at the IDWeek conference in Washington, D.C.

20 Oct 2022

Study identifies gene mutations that impact radiation resistance and sensitivity

A new Northwestern Medicine study identifies common and rare gene mutations that impact radiation resistance and sensitivity, an important step toward providing more individualized and effective radiotherapy for patients with cancer.

20 Oct 2022

Clinical Trial News and Research

Immune checkpoint therapy may be beneficial in certain cases of severe COVID-19

UC San Diego participates in national trial to assess potential treatment for human monkeypox

Study shows potential for eliminating surgery in a small subset of breast cancer patients

Low-carb diet may be a useful approach for preventing and treating Type 2 diabetes

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

Study finds new drug combination to be more effective against complicated urinary tract infections

New evidence on how intermittent fasting impacts women's reproductive hormones

Study offers a combination treatment option for patients with oligometastatic prostate cancer

Interrupting prolonged sitting with periodic activity "snacks" may help maintain muscle mass, study says

Researchers streamline way to manufacture CAR T-cells in just 24 hours

More intensive prostate cancer screening may reduce the risk of metastatic cancer later

Meeting with a medical physicist reduces patients' radiation treatment-related stress

Combination of radiation and systemic therapy can prolong survival for advanced liver cancer patients

Clinical trial confirms the safety, efficacy of shortened radiation therapy for high-risk prostate cancer patients

FLASH radiotherapy may hold promise as a potential treatment for tough-to-kill tumors

Treating high-risk, asymptomatic bone metastases with radiation may reduce pain, extend survival

Duke biomedical engineers develop a two-pronged approach to treating pancreatic cancer

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Three-dose course of the hepatitis B vaccine fully protects adults living with HIV

Study identifies gene mutations that impact radiation resistance and sensitivity

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