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Mice tails play a key role in preventing falls and improving balance

Why do mice have tails? The answer to this is not as simple as you might think. New research from the Okinawa Institute of Science and Technology (OIST) has shown that there's more to the humble mouse tail than previously assumed.

6 Nov 2024

Gene editing with CRISPR may introduce new defects

The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease.

6 Nov 2024

How a ketogenic diet could reduce autoimmune disease severity through host-microbiome interactions

This study uncovers the ketogenic diet's effects on the microbiome, revealing its potential to mitigate autoimmune diseases through metabolic pathways.

6 Nov 2024

CHiTA assay identifies functional twister ribozymes

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA - a single-stranded molecule similar in many ways to DNA - like some modern viruses. This is because, like DNA, RNA can carry genetic information, but, like a protein, it can also act as an enzyme, initiating or accelerating reactions.

5 Nov 2024

Advances in neutropenia research could pave the way for better treatments

Neutropenia is a condition in which there are not enough neutrophils, a type of white blood cell, in the blood.

5 Nov 2024

Genetic and environmental drivers shape early type 1 diabetes risk in children

Researchers from the TEDDY study highlight how specific genetic and environmental factors may drive early autoimmunity linked to type 1 diabetes in children, emphasizing distinct patterns for different autoantibodies.

5 Nov 2024

Machine learning identifies key genes linking rheumatoid arthritis and osteoporosis

Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the joints and can result in pain, swelling, and damage to the cartilage and bone.

5 Nov 2024

Multi-omics-based classification of gastrointestinal stromal tumors lays groundwork for precision treatment

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these tumors.

5 Nov 2024

Werner syndrome gene plays key role in maintaining cellular organization and DNA stability

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20 on October 17, 2024, entitled, "Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells."

5 Nov 2024

Research links ultra-processed foods to accelerated biological aging

A study conducted by the Research Unit of Epidemiology and Prevention at the I.R.C.C.S. Neuromed in Pozzilli, in collaboration with the LUM University of Casamassima, shows that high consumption of ultra-processed foods is associated with the acceleration of biological aging, regardless of the nutritional quality of the diet.

5 Nov 2024

New Alzheimer's guidelines focus on risk, not diagnosis, in healthy adults

Researchers from the International Working Group recommend categorizing biomarker-positive, cognitively normal individuals as "at risk" for Alzheimer's to avoid unnecessary diagnoses and emphasize preventive care.

4 Nov 2024

Long sitting hours could accelerate aging in young adults

Between long commutes, Zoom-packed workdays and evenings of streaming and scrolling, millennials now spend more than 60 hours per week sitting, potentially boosting their heart disease risk and accelerating other signs of aging, according to new CU Boulder and University of California Riverside research.

4 Nov 2024

New model sheds light on APOE4's role in Alzheimer's pathology

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein - the most important genetic risk factor for Alzheimer's disease - the same cells cause harmful inflammation and clumps of misfolded proteins, according to a new study by scientists at Gladstone Institutes.

4 Nov 2024