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The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Researchers from Ireland used human bronchial epithelium models to evaluate the ability of a novel proprietary formulation called ViruSAL to inhibit SARS-CoV-2 infections.

12 Oct 2022

Neuropilin 2 identified as a novel regulator of distal colonic smooth muscle motility

Neuropilin 2 identified as a novel regulator of distal colonic smooth muscle motility

Colonic motility disorders, especially problems associated with constipation and diarrhea, are common in adults and children, greatly impacting quality of life.

11 Oct 2022

Antibody response trajectories among solid organ transplant recipients in association with mycophenolate mofetil administration

Antibody response trajectories among solid organ transplant recipients in association with mycophenolate mofetil administration

Researchers explored the trajectory of antibody (Ab) titers after coronavirus disease 2019 (COVID-19) vaccination among solid organ transplant recipients (SOTs) with or without mycophenolate mofetil (MMF), or withdrawn from MMF.

11 Oct 2022

Are men or women impacted more by adverse reactions to prescription drug treatments?

Are men or women impacted more by adverse reactions to prescription drug treatments?

Recently, researchers presented an overview of sex-based differences in adverse drug reactions (ADRs) based on epidemiology, technique, and underlying mechanism data.

11 Oct 2022

Individuals with inflammatory breast cancer face a higher risk brain metastases

Individuals with inflammatory breast cancer face a higher risk brain metastases

New research indicates that among individuals with breast cancer, those with a rare subtype called inflammatory breast cancer face a higher risk that their cancer will spread, or metastasize, to the brain.

10 Oct 2022

Metformin reduces risk of severe COVID-19 in diabetic patients

Metformin reduces risk of severe COVID-19 in diabetic patients

A new study determines whether antidiabetic agents can reduce complications in COVID-19 patients with diabetes.

10 Oct 2022

Evaluating graphene field effect biosensor for ultraprecise and simultaneous influenza and SARS-CoV-2 detection

Evaluating graphene field effect biosensor for ultraprecise and simultaneous influenza and SARS-CoV-2 detection

In a new study, researchers developed an antibody (Ab)-modified graphene field effect transistor (GFET)-based biosensor for ultraprecise and rapid influenza A virus (IAV) and SARS-CoV-2 protein detection and differentiation.

10 Oct 2022

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

In a new study, researchers investigated the breadth and longevity of immunity induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure among the Kenyan population.

10 Oct 2022

Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

In a new study, researchers compared serum cytokine expression among healthy individuals and those with PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)].

10 Oct 2022

UMSOM researchers identify how multiple genes of SARS-CoV-2 affect disease severity

UMSOM researchers identify how multiple genes of SARS-CoV-2 affect disease severity

University of Maryland School of Medicine researchers have identified how multiple genes of SARS-CoV-2 affect disease severity, which could lead to new ways in how we develop future vaccines or develop newer treatments.

7 Oct 2022

Opioid receptor levels in brown fat found to be dependent on the length of daylight hours

Opioid receptor levels in brown fat found to be dependent on the length of daylight hours

Researchers from the Turku PET Centre, Finland, have observed that the length of daylight hours impacts opioid receptor levels in brown fat.

7 Oct 2022

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Researchers examined the replicative capacity of seven SARS-CoV-2 isolates in 17 cell lines to understand their phenotypic variations and host range.

7 Oct 2022

Vaccine-induced neutralizing and non-neutralizing antibody activity against SARS-CoV-2

Vaccine-induced neutralizing and non-neutralizing antibody activity against SARS-CoV-2

A new study demonstrated that vaccine-induced antibody functions against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diminish with age.

7 Oct 2022

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Intranasal vaccine represents an effective broad-spectrum COVID-19 vaccine strategy

Researchers evaluated the efficacy of dNS1-RBD, a novel intranasal COVID-19 vaccine.

6 Oct 2022

The neuroprotective potential of Cannabis sativa L. against Alzheimer's disease

The neuroprotective potential of Cannabis sativa L. against Alzheimer's disease

A recent study assesses the neuroprotective potential of the active constituents of cannabis in treating dementia and Alzheimer's disease.

6 Oct 2022

Researchers discover potential therapeutic target for deadly brain tumors

Researchers discover potential therapeutic target for deadly brain tumors

Researchers at VCU Massey Cancer Center discovered a cellular partnership that drives the growth of deadly brain tumors and could potentially serve as a novel target for disease treatment.

5 Oct 2022

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

In a new study, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of SARS-CoV-2 on the vascular endothelial cells.

5 Oct 2022

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Researchers engineered biparatopic nanobodies against SARS-CoV-2.

5 Oct 2022

Omicron reduces host antibody response by lower B-cell antigenicity

Omicron reduces host antibody response by lower B-cell antigenicity

A new study explores the functional relevance of some Omicron mutations in terms of their ability to escape neutralizing antibody responses.

4 Oct 2022

Antibody escape mutations of SARS-CoV-2 BA.2.75

Antibody escape mutations of SARS-CoV-2 BA.2.75

A new study discusses how immune escape mutations allow a recent SARS-CoV-2 variant to evade neutralizing antibodies and cause breakthrough infections.

4 Oct 2022

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