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Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

A novel mAb against the SARS-CoV-2 RBD through a hybridoma technique, followed by chimerization and expression in plants.

22 Nov 2022

Experts highlight the expanding presence and emerging risks from three endemic fungal diseases

Infectious diseases expert George Thompson has been studying and treating fungal diseases for over two decades. He monitors their spread, symptoms and relative risks.

22 Nov 2022

Study provides insight into the natural course of COVID-19 infection in pregnancy

A UT Southwestern study of more than 1,300 pregnant women diagnosed with COVID-19 found that just 1 in 10 developed moderate, severe, or critical illness and that COVID-19 symptoms and severity were similar across all trimesters.

22 Nov 2022

NIH's new website allows users to anonymously report COVID-19 test results

Reporting a positive or negative test result just became easier through a new website from the National Institutes of Health. MakeMyTestCount.org, developed through NIH's Rapid Acceleration of Diagnostics (RADx) Tech program, allows users to anonymously report the results of any brand of at-home COVID-19 test.

22 Nov 2022

SARS-CoV-2 seroprevalence in domestic cats has increased over time

Researchers evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission among domestic cats in the United Kingdom (UK).

22 Nov 2022

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

In a recent study, researchers used proteomic analysis to identify novel immune cell phenotypes associated with severe coronavirus disease 2019 (COVID-19).

22 Nov 2022

Males exposed to COVID-19 in utero may be at elevated risk of neurodevelopmental disorders

Researchers investigated the impact of SARS-CoV-2 exposure in utero on the neurodevelopment of children.

22 Nov 2022

New EULAR recommendations for screening and treating infections in AIIRD patients

It is already known that people who are immunocompromised are more prone to infections. Chronic and opportunistic infections are often found in people with an AIIRD, and may be linked to some of the immunosuppressive and immunomodulatory treatments used to treat these rheumatic diseases.

22 Nov 2022

Effects of implemented vaccine rollout strategies on spread of SARS-CoV-2, subsequent global burden of disease, and emergence of novel variants

Researchers conducted a retrospective analysis to investigate the impact of vaccine-sharing strategies on the heterogenous global distribution of COVID-19 vaccines.

22 Nov 2022

The separate and combined associations of coffee and tea consumption with all-cause and cause-specific mortality

Researchers investigated the association between individual and combined coffee and tea consumption and all-cause and cause-specific mortality, such as those due to cardiovascular, respiratory, and digestive diseases.

22 Nov 2022

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Researchers explored active and passive vaccination among children against respiratory syncytial virus (RSV).

22 Nov 2022

US experienced higher COVID-19 mortality during delta and omicron waves

A recent study estimates coronavirus disease 2019-related mortality and excess all-cause mortality in the US and 20 peer countries during the delta and omicron waves of infection.

22 Nov 2022

Treating long covid is rife with guesswork

Medical equipment is still strewn around the house of Rick Lucas, 62, nearly two years after he came home from the hospital. He picks up a spirometer, a device that measures lung capacity, and takes a deep breath — though not as deep as he'd like.

22 Nov 2022

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

Researchers assessed the effectiveness of SARS-CoV and SARS-CoV-2 envelope proteins against HIV-1.

22 Nov 2022

Exploring antibiotic resistance in the EU

Antibiotic resistance is one of the greatest threats to global human health and to development.

22 Nov 2022

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

In a recent study published in the journal Advanced Science, researchers developed molecularly imprinted nanoparticles (nanoMIPs) with broad-spectrum activity against lethal viruses.

21 Nov 2022

Elevated incidence and risk for a new diagnosis of diabetes after COVID-19

In a recent study published in the journal BMC Medicine, researchers estimated the prevalence of new-onset diabetes following coronavirus disease 2019 (COVID-19).

21 Nov 2022

The WHO announces four MERS cases from Saudi Arabia in recent weeks

A recent disease outbreak alert released by the World Health Organization (WHO) reported four laboratory-confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) from three regions in the Kingdom of Saudi Arabia.

21 Nov 2022

Study finds no benefits from angiotensin receptor blocker treatment for COVID-19

In a recent study published in the BMJ, researchers conducted a phase three, multicenter, randomized controlled trial to evaluate the effect of using angiotensin receptor blockers that disrupt the renin-angiotensin system on the clinical outcomes of individuals with coronavirus disease 2019 (COVID-19).

21 Nov 2022

Respiratory News and Research

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

Experts highlight the expanding presence and emerging risks from three endemic fungal diseases

Study provides insight into the natural course of COVID-19 infection in pregnancy

NIH's new website allows users to anonymously report COVID-19 test results

SARS-CoV-2 seroprevalence in domestic cats has increased over time

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

Males exposed to COVID-19 in utero may be at elevated risk of neurodevelopmental disorders

New EULAR recommendations for screening and treating infections in AIIRD patients

Effects of implemented vaccine rollout strategies on spread of SARS-CoV-2, subsequent global burden of disease, and emergence of novel variants

The separate and combined associations of coffee and tea consumption with all-cause and cause-specific mortality

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

US experienced higher COVID-19 mortality during delta and omicron waves

Treating long covid is rife with guesswork

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

Exploring antibiotic resistance in the EU

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

Elevated incidence and risk for a new diagnosis of diabetes after COVID-19

The WHO announces four MERS cases from Saudi Arabia in recent weeks

Study finds no benefits from angiotensin receptor blocker treatment for COVID-19

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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