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UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

UW Medicine genome scientists were among the leading contributors to the publication of the first complete, gapless sequence of a human genome announced this week by the National Human Genome Research Institute.

31 Mar 2022

Drug-resistant, pathogenic yeasts found on surfaces of apples and other fruits

When they're prepared for transport, apples and other fruits are often treated with a fungicide to prevent spoilage and extend shelf life.

31 Mar 2022

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors.

31 Mar 2022

Inconsistency in disease severity across SARS-CoV-2 variants

Researchers determine how the severity of successively dominant SARS-CoV-2 variants has changed since the beginning of the pandemic.

30 Mar 2022

Scientists create a biobank of 87 triple-negative breast cancer organoids

It's the cancer version of "mini me." Cold Spring Harbor Laboratory (CSHL) Professor David Spector, among others, has developed organoids, which are miniature, three-dimensional copies of cancers. Organoids can be derived from cancer or healthy cells.

30 Mar 2022

Clinical trials for experimental HIV vaccines based on mRNA technology begin in United States

Scientists urge African leaders to demand fair licensing following clinical trials of an HIV vaccine candidate.

30 Mar 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

Study identifies 10 new genetic regions linked with Brugada syndrome

A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.

30 Mar 2022

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Researchers proposed an optimal system to generate SARS-CoV-2 virus-like particles for examining viral assembly and entry into target host cells.

30 Mar 2022

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

A recent study analyzed the polymorphisms in the SARS-CoV-2 spike proteins' S1/S2 subunits.

30 Mar 2022

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

Researchers demonstrated that E proteins of β-coronaviruses could restrict HIV-1 infection.

30 Mar 2022

ProteoGenix launches new XtenCHOTM Transient CHO Expression System to improve biologics development

ProteoGenix, a contract research organization specialized in biologics discovery and bioproduction, announces the launch of its XtenCHOTM Transient Expression System.

From ProteoGenix 30 Mar 2022

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

A new study shows that multiple variants of this virus may coinfect the same patient, using both genomic sequencing data and computational models.

30 Mar 2022

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes respiratory coronavirus disease 2019 (COVID-19) triggered an unprecedented public health emergency. Human mobility patterns were fundamental to the spread of SARS-CoV-2 globally. The situation is particularly acute in a country like Saudi Arabia, which has seen more than 750,000 cases and over 9,000 deaths as of March 30th, 2022.

29 Mar 2022

Study shows clinical value of pharmacogenomic testing for patients with treatment-resistant depression

Pharmacogenetic testing was associated with nearly a two-fold (89 per cent) increase in remission rates compared to treatment as usual in a Centre for Addiction and Mental Health- (CAMH-)led clinical study just published in the journal Translational Psychiatry.

29 Mar 2022

A bioinformatics approach for detecting SARS-CoV-2 co-infections

Researchers discuss a novel bioinformatics-based method for the detection of SARS-CoV-2 co-infections with the Delta and Omicron variants.

29 Mar 2022

Researchers report progress en route to developing a hypoallergenic cat

Researchers at InBio (formerly Indoor Biotechnologies), a biotech company in Virginia, report progress en route to developing a hypoallergenic cat – or at least treating patients with allergies to the domestic cat – in a new article published online in The CRISPR Journal.

29 Mar 2022

$4 million program launched to find transformative therapies for ADNP syndrome

Researchers at the UC Davis MIND Institute are launching a $4 million program to find transformative therapies for ADNP syndrome. The rare genetic condition causes developmental delays and can affect the brain, heart, gastrointestinal system and more.

29 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Characterization of the different expressed RNAseq variants in SARS-CoV-2 infected patients

A recent study analyzed the RNAseq variants of COVID-19 patients and healthy donors.

29 Mar 2022

Genome News and Research

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

Drug-resistant, pathogenic yeasts found on surfaces of apples and other fruits

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

Inconsistency in disease severity across SARS-CoV-2 variants

Scientists create a biobank of 87 triple-negative breast cancer organoids

Clinical trials for experimental HIV vaccines based on mRNA technology begin in United States

A summary of SARS-CoV-2 RNA-protein interactome studies

Study identifies 10 new genetic regions linked with Brugada syndrome

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

Study shows that the SARS-CoV-2 envelope protein potently restricts HIV-1 infection

ProteoGenix launches new XtenCHOTM Transient CHO Expression System to improve biologics development

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

SARS-CoV-2 nucleocapsid protein linked to COVID-19 severity

Study shows clinical value of pharmacogenomic testing for patients with treatment-resistant depression

A bioinformatics approach for detecting SARS-CoV-2 co-infections

Researchers report progress en route to developing a hypoallergenic cat

$4 million program launched to find transformative therapies for ADNP syndrome

The different actions of CBD in SARS-CoV-2 infection

Characterization of the different expressed RNAseq variants in SARS-CoV-2 infected patients

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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