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Scientists pinpoint genetic traits of cells that give rise to gliomas

A multi-institutional team of researchers have pinpointed the genetic traits of the cells that give rise to gliomas - the most common form of malignant brain cancer. The findings, which appear in the journal Cell Reports, provide scientists with rich new potential set of targets to treat the disease.

4 Jun 2013

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails.

1 Jun 2013

FDA accepts Teva Pharmaceutical's sNDA for COPAXONE

Teva Pharmaceutical Industries Ltd. announced today that the U.S. Food and Drug Administration has accepted for review the company's supplemental new drug application for COPAXONE (glatiramer acetate injection) 40mg/ 1mL, a higher concentration dose of COPAXONE that offers a less frequent three times a week dosing regimen administered subcutaneously for patients with relapsing-remitting multiple sclerosis.

31 May 2013

Cancer: The No. 1 health concern among middle-income Americans

Cancer is the No. 1 health concern among our country's middle-income Americans, according to a new study released by Washington National Institute for Wellness Solutions.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

Research data on AMPYRA Extended Release Tablets to be presented at CMSC and ACTRIMS meeting

Acorda Therapeutics, Inc. will present new research data on AMPYRA (dalfampridine) Extended Release Tablets, 10 mg at the 5th Cooperative Meeting of the Consortium of Multiple Sclerosis Centers and Americas Committee for Treatment and Research in Multiple Sclerosis, being held in Orlando, FL, May 29 - June 1.

28 May 2013

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Scientists at UC Irvine reported this week that a synthetic compound ShK-186, originally derived from a sea anemone toxin, has been found to enhance metabolic activity and shows potential as a treatment for obesity and insulin resistance.

28 May 2013

Researchers identify mutations in new genes that might be associated with ALS disease

Researchers at the Stanford University School of Medicine have identified mutations in several new genes that might be associated with the development of spontaneously occurring cases of the neurodegenerative disease known as amyotrophic lateral sclerosis, or ALS.

27 May 2013

Research findings reveal promising new anti-addiction drug

Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine's effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice.

23 May 2013

Newly discovered immune protein has potential to stop or reverse type 1 diabetes

Melbourne researchers have identified an immune protein that has the potential to stop or reverse the development of type 1 diabetes in its early stages, before insulin-producing cells have been destroyed.

21 May 2013

Biogen Idec seeks FDA BLA approval for PLEGRIDY to treat multiple sclerosis

Today Biogen Idec announced it has submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for approval of PLEGRIDY (peginterferon beta-1a), the company's pegylated subcutaneous injectable candidate for relapsing forms of multiple sclerosis (RMS).

21 May 2013

XenoPort's Arbaclofen placarbil fails to meet co-primary endpoints in Phase 3 clinical trial

XenoPort, Inc. announced today top-line results from its pivotal Phase 3 clinical trial of arbaclofen placarbil for the treatment of patients with spasticity due to multiple sclerosis.

20 May 2013

UC Davis scientists detect novel molecular target for multiple sclerosis

Working with lab mice models of multiple sclerosis, UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved medications against MS.

17 May 2013

Insero Health announces top-line Phase Ib trial results of INS001 in patients with drug-resistant epilepsy

Insero Health, Inc., a company developing natural compounds to address unmet medical needs in epilepsy and related neurological disorders, is today reporting top-line results from a Phase Ib trial of its lead compound INS001 in patients with drug-resistant epilepsy.

17 May 2013

Northwestern University scientists identify gene important to morning wake-up call

Northwestern University scientists have shown a gene involved in neurodegenerative disease also plays a critical role in the proper function of the circadian clock.

17 May 2013

Research breakthrough: Human skin cells becomes embryonic stem cells

Scientists at Oregon Health & Science University and the Oregon National Primate Research Center have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body.

16 May 2013

Implications for manipulating immune response for some inflammatory disorders

Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory mediators.

14 May 2013

Research findings may pave way to new treatment for Alzheimer's disease in humans

A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment.

14 May 2013

Cancers physically alter cells in lymphatic system to promote the spread of disease

Researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center report that cancers physically alter cells in the lymphatic system - a network of vessels that transports and stores immune cells throughout the body - to promote the spread of disease, a process called metastasis.

14 May 2013

Drug cost disparities, small business worries continue to surround health law's implementation

The Associated Press reports on the emergence of concerns regarding the health law and drug cost disparities. Meanwhile, other news outlets report on how employers continue to have angst about the measure's price tag.

14 May 2013

Sclerosis News and Research

Scientists pinpoint genetic traits of cells that give rise to gliomas

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

FDA accepts Teva Pharmaceutical's sNDA for COPAXONE

Cancer: The No. 1 health concern among middle-income Americans

Transplantation of human stem cells improves muscle function in rats used to model ALS

Research data on AMPYRA Extended Release Tablets to be presented at CMSC and ACTRIMS meeting

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Researchers identify mutations in new genes that might be associated with ALS disease

Research findings reveal promising new anti-addiction drug

Newly discovered immune protein has potential to stop or reverse type 1 diabetes

Biogen Idec seeks FDA BLA approval for PLEGRIDY to treat multiple sclerosis

XenoPort's Arbaclofen placarbil fails to meet co-primary endpoints in Phase 3 clinical trial

UC Davis scientists detect novel molecular target for multiple sclerosis

Insero Health announces top-line Phase Ib trial results of INS001 in patients with drug-resistant epilepsy

Northwestern University scientists identify gene important to morning wake-up call

Research breakthrough: Human skin cells becomes embryonic stem cells

Implications for manipulating immune response for some inflammatory disorders

Research findings may pave way to new treatment for Alzheimer's disease in humans

Cancers physically alter cells in lymphatic system to promote the spread of disease

Drug cost disparities, small business worries continue to surround health law's implementation

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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