Genes News and Research

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Study identifies 9 novel genes linked to gestational diabetes

The largest genetic study of gestational diabetes to date has led to a discovery of nine novel genetic regions linked to this severe and common pregnancy complication.

5 Jan 2024

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

A new study in Nature described Nav1.7 as a key regulatory molecule in cartilage cells and reported the effectiveness of Nav1.7 blockade in reducing pain and slowing progression in OA.

5 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

YAP and TAZ proteins guide bone development in the womb

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

4 Jan 2024

Study: Two-thirds of babies with sickle cell disease are born to mothers living in disadvantaged areas

As if starting life with a potentially disabling genetic blood disease wasn't enough, a study shows that almost two-thirds of babies born with sickle cell disease are born to mothers who live in disadvantaged areas.

4 Jan 2024

New study highlights the work of biobank at the Colorado Center for Personalized Medicine

A new peer-reviewed study in the American Journal of Human Genetics highlights the work of the biobank at the Colorado Center for Personalized Medicine (CCPM), a world-class site for precision medicine in research and clinical care created in partnership with the University of Colorado Anschutz Medical Campus and UCHealth.

4 Jan 2024

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.

4 Jan 2024

Research identifies genetic connection between anorexia and morning chronotype

New research indicates that the eating disorder anorexia nervosa is associated with being an early riser, unlike many other disorders that tend to be evening-based such as depression, binge eating disorder and schizophrenia.

4 Jan 2024

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins - and ultimately affect aging.

4 Jan 2024

Missing proteins explain century-old mystery of scalp skin absence in children

Children with the condition aplasia cutis congenita (ACC) are born with the absence of skin along the midline of the scalp.

3 Jan 2024

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Study explores the potential of EZH2 inhibitors GSK126 and Tazemetostat in stimulating β-cell regeneration from pancreatic ductal progenitor cells, offering a novel therapeutic approach for Type 1 Diabetes.

3 Jan 2024

New method illuminates intricate interactions of the synaptonemal complex in nematodes

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability.

3 Jan 2024

Study maps gene network orchestrating complex process of IgG glycosylation in aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Mapping of the gene network that regulates glycan clock of ageing."

3 Jan 2024

Study: High-fat diets impact genes in the intestines, brain, and immune system

A UC Riverside study to motivate your new year's resolutions: it demonstrates that high-fat diets affect genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system, brain function, and potentially COVID-19 risk.

3 Jan 2024

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

Mapping tiny corneal nerves to untangle ocular mysteries

Consider the cornea if you will – and most people won't unless they're having a problem. It is the transparent front surface of the eye which allows vision by focusing light as it enters.

3 Jan 2024

"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score.

3 Jan 2024

Genes News and Research

Study identifies 9 novel genes linked to gestational diabetes

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

Unlocking the power of diet: How miRNAs influence health and disease

YAP and TAZ proteins guide bone development in the womb

Study: Two-thirds of babies with sickle cell disease are born to mothers living in disadvantaged areas

New study highlights the work of biobank at the Colorado Center for Personalized Medicine

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Research identifies genetic connection between anorexia and morning chronotype

Early-acting autophagy genes extend lifespan through alternative "garbage disposal" pathway in neurons

Missing proteins explain century-old mystery of scalp skin absence in children

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

New method illuminates intricate interactions of the synaptonemal complex in nematodes

Study maps gene network orchestrating complex process of IgG glycosylation in aging

Study: High-fat diets impact genes in the intestines, brain, and immune system

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Mapping tiny corneal nerves to untangle ocular mysteries

"Genetic priority score" promises to revolutionize drug development

Spicing up the fight: Saffron's powerful impact on prostate cancer revealed

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

Previously unidentified protein variant shields against Parkinson's disease

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