Genetic Engineering News and Research

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New understanding of what makes a major global bacterial infection deadly

Researchers believe they have discovered why a bacterial lung infection is so lethal in the early stages, and it's not what medical authorities had thought, according to research published in the journal Immunity.

28 Aug 2007

Fat mice gain protection against diabetes

The world's fattest mice can overeat without developing insulin resistance or diabetes thanks to a glut of a key hormone, a dichotomy that helps explain why not all obese people are diabetic, a UT Southwestern Medical Center researcher has found.

24 Aug 2007

Potential new strategies for treating obsessive compulsive disorder

Using genetic engineering, researchers have created an obsessive-compulsive disorder (OCD) - like set of behaviors in mice and reversed them with antidepressants and genetic targeting of a key brain circuit.

24 Aug 2007

Vaccine suppresses aggregates of tau protein - implications for Alzheimer's

A new study by NYU Medical Center researchers shows for the first time that the immune system can combat the pathological form of tau protein, a key protein implicated in Alzheimer's disease.

22 Aug 2007

Genetic engineering offers promising new approaches to improve dietary iron intake

Using selective plant breeding and genetic engineering could be used to reduce the incidence of iron deficiency worldwide by improving the quality of dietary iron, conclude authors of a Seminar in this week’s edition of The Lancet.

13 Aug 2007

Researchers turn mouse into factory for human liver cells

Oregon Health & Science University researchers have figured out how to turn a mouse into a factory for human liver cells that can be used to test how pharmaceuticals are metabolized.

11 Aug 2007

Scientists find mechanisms controlling metastasis of breast cancer cells

When cancer cells dissociate from the original tumor and migrate via the blood stream to colonize distant organs, is the main cause of cancer death.

9 Aug 2007

New treatment for glaucoma shows promise

Iowa State University researchers have developed a new technique that successfully treated rats for blindness caused by glaucoma.

3 Aug 2007

Insulin produced in genetically modified lettuce relieves diabetes in mice

Capsules of insulin produced in genetically modified lettuce could hold the key to restoring the body's ability to produce insulin and help millions of Americans who suffer from insulin-dependent diabetes, according to University of Central Florida biomedical researchers.

1 Aug 2007

First mouse model of schizophrenia

Johns Hopkins researchers have genetically engineered the first mouse that models both the anatomical and behavioral defects of schizophrenia, a complex and debilitating brain disorder that affects over 2 million Americans.

1 Aug 2007

Directed nanoparticles deliver gene therapy

After binding DNA segments to tiny iron-containing spheres called nanoparticles, researchers have used magnetic fields to direct the nanoparticles into arterial muscle cells, where the DNA could have a therapeutic effect.

31 Jul 2007

Tetrabenazine protects brain cells in Huntington's disease model

A drug used in some countries to treat the symptoms of Huntington's disease prevents death of brain cells in mice genetically engineered to mimic the hereditary condition, UT Southwestern Medical Center researchers have found.

25 Jul 2007

Hemoglobin-based oxygen carrier shows promise as treatment for sickle cell disease

Studies in mice suggest that a red blood cell substitute based on human hemoglobin could be a promising new treatment for sickle cell disease in humans.

24 Jul 2007

Good diet + exercise = less insulin in the brain and a longer life!

Scientists in the U.S. say reducing the action of insulin in the brain could well be the secret to longevity.

22 Jul 2007

Reducing insulin signaling in the brain can prolong lifespan

One route to a long and healthy life may be establishing the right balance in insulin signaling between the brain and the rest of the body, according to new research from Children's Hospital Boston.

20 Jul 2007

Xenotransplantation from pigs getting closer

Experiments using pigs genetically engineered for compatibility with the human immune system have raised hopes that cross-species transplantation could soon become an option for patients with diabetes and other currently incurable diseases.

20 Jul 2007

Anti-cancer gene p53 doubles up as anti-ageing agent

The latest research suggests that one of the genes that protects us from cancer may also help delay the ageing process.

19 Jul 2007

Preconditioning protects brain from stroke

Challenging brain tissue with a small noxious stimulus beforehand gives it a resilience that can lessen damage to blood vessels during a stroke, report researchers at Weill Cornell Medical College in New York City.

18 Jul 2007

Suicide gene therapy for cancer

Cutting-edge research at South Dakota State University may yield a new therapy that targets only cancer cells, leaving healthy cells unharmed.

18 Jul 2007

Key mechanism to emergence of deadly strep bacteria discovered

The incidence of serious strep infections has risen dramatically in the last three decades, and this increase is largely attributed to the spread around the globe of a single strain of strep known as the invasive M1T1 clone.

16 Jul 2007