Clinical Trial News and Research

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New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

Artificial intelligence could help fast-track dementia diagnosis

Different forms of dementia could be spotted sooner and more easily by analyzing recordings of patients' electrical brain activity using artificial intelligence (AI), according to new research.

21 Sep 2022

Large clinical trial compares four drugs commonly used to treat type 2 diabetes

In a large clinical trial that directly compared four drugs commonly used to treat type 2 diabetes, researchers found that insulin glargine and liraglutide performed the best of four medications approved by the U.S. Food and Drug Administration to maintain blood glucose levels in the recommended range.

21 Sep 2022

Formula may be right for infants, but experts warn that toddlers don’t need it

Formulas for toddlers are a burgeoning business in the United States: Sales of the drinks more than doubled in recent years as companies convinced parents that their little ones needed the liquid boost.

21 Sep 2022

Cutting protein intake can help control obesity, diabetes and hypertension

Cutting protein intake can help control metabolic syndrome and some of its main symptoms, such as obesity, diabetes and high blood pressure (hypertension), according to a study conducted by researchers in Brazil and Denmark to compare the effects of protein and calorie restriction diets in humans.

20 Sep 2022

Overload of stress granules enables the growth of obesity-related pancreatic cancer

Obesity is a known risk factor for at least 13 types of cancer, in part because it creates ever-present inflammatory state. For years, one researcher has wondered if there's more to the story than inflammation.

20 Sep 2022

New catheter leads to a remarkable reduction in pulmonary artery obstruction

A device known as the BASHIR™ Endovascular Catheter (THROMBOLEX, Inc.) significantly reduces the size of blood clots lodged in the pulmonary arteries, leading to improvement in heart function in patients with pulmonary embolism, researchers from the Lewis Katz School of Medicine at Temple University announced in a Late-Breaking Innovation session at the 2022 Transcatheter Cardiovascular Therapeutics (TCT) conference in Boston.

19 Sep 2022

New radiation therapy option may extend lifespan, improve quality of life for certain brain cancer patients

UC San Diego Health is the first hospital system in San Diego to offer a new, highly targeted and precisely placed radiation therapy that delays tumor regrowth while protecting healthy tissue in patients with brain cancer.

19 Sep 2022

Rheumatoid arthritis drug can reduce the risk of deterioration in myasthenia gravis

Early intervention with rituximab, a drug used in the treatment of rheumatoid arthritis (RA), can reduce the risk of deterioration in myasthenia gravis, an autoimmune disease that causes loss of muscle control.

19 Sep 2022

Daily multivitamin improves cognitive function in seniors

In a recent study published in the journal Alzheimer's & Dementia, researchers in the United States investigated whether daily administration of a cocoa extract (CE, comprising 500 mg flavanols, including 80 mg epicatechins, 50 mg/day theobromine (50 mg/day), and 15mg/day caffeine) and/or an MVM (multivitamin-mineral) for three years protected cognitive functions among older men and women.

18 Sep 2022

UW Medicine researchers seek participants for Phase 3 clinical trial of a drug to treat monkeypox

UW Medicine researchers are recruiting participants for a Phase 3 clinical trial of a drug to treat the monkeypox virus.

16 Sep 2022

Itchy eczema in children finally gets relief

This is the first large-scale, randomized, placebo-controlled trial of a monoclonal antibody in any skin disease, including eczema, in children as young as six months. The study, which included 31 sites in Europe and North America, was published in The Lancet.

16 Sep 2022

BU researcher awarded $7.2 million grant to develop mAb-based contraceptive products

Deborah Jean Anderson, PhD, professor of medicine at Boston University School of Medicine, has received a four-year, $7.2 million grant from the NIH's National Institute of Child Health and Human Development renewing support for a Contraceptive Research Center at BUSM to further her research to develop innovative monoclonal antibody (mAb)-based contraceptive and multipurpose prevention technology (MPT) products.

15 Sep 2022

R21/Matrix-M booster maintains high efficacy against first and multiple episodes of clinical malaria

The phase 1/2b clinical trial on R21/Matrix-M malaria vaccine has recently reported the safety and efficacy of booster vaccination at 12 months.

15 Sep 2022

Simple phone-based outreach strategy can help engage low-income smokers to try quitting tobacco

New findings published in Nicotine & Tobacco Research show a simple, but valuable approach can help engage low-income smokers to try quitting tobacco.

14 Sep 2022

Researchers use data from wearables to predict outcomes of depression treatment

Over the past several years, managing one's mental health has become more of a priority with an increased emphasis on self-care. Depression alone affects more than 300 million people worldwide annually.

13 Sep 2022

Vitamin D3 or omega-3 fatty acid supplements do not prevent frailty in older adults

Frailty is defined as reduced physiological reserve and ability to cope with acute stresses. Up to half of adults over the age of 85 live with frailty and thus, preventative measures are greatly needed.

13 Sep 2022

Immunotherapy before surgery improves outcomes in many patients with stage II–IV cutaneous squamous cell carcinoma

In an international, multicenter Phase II clinical trial led by The University of Texas MD Anderson Cancer Center, 63.3% of patients with stage II–IV cutaneous squamous cell carcinoma (CSCC) saw their tumors nearly or completely disappear when treated with immunotherapy before surgery.

13 Sep 2022

$Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer$

Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer.

13 Sep 2022

New software application predicts the likelihood of genetic mutation in dilated cardiomyopathy

Scientists at the CNIC and Hospital Universitario Puerta de Hierro in Majadahonda have developed a software application that predicts the likelihood that a case of dilated cardiomyopathy is caused by a genetic mutation. The research was carried out in collaboration with hospitals in Spain, Italy, and the Netherlands.

13 Sep 2022

Clinical Trial News and Research

New genetically-targeted MND therapy could be a turning point for patient care

Artificial intelligence could help fast-track dementia diagnosis

Large clinical trial compares four drugs commonly used to treat type 2 diabetes

Formula may be right for infants, but experts warn that toddlers don’t need it

Cutting protein intake can help control obesity, diabetes and hypertension

Overload of stress granules enables the growth of obesity-related pancreatic cancer

New catheter leads to a remarkable reduction in pulmonary artery obstruction

New radiation therapy option may extend lifespan, improve quality of life for certain brain cancer patients

Rheumatoid arthritis drug can reduce the risk of deterioration in myasthenia gravis

Daily multivitamin improves cognitive function in seniors

UW Medicine researchers seek participants for Phase 3 clinical trial of a drug to treat monkeypox

Itchy eczema in children finally gets relief

BU researcher awarded $7.2 million grant to develop mAb-based contraceptive products

R21/Matrix-M booster maintains high efficacy against first and multiple episodes of clinical malaria

Simple phone-based outreach strategy can help engage low-income smokers to try quitting tobacco

Researchers use data from wearables to predict outcomes of depression treatment

Vitamin D3 or omega-3 fatty acid supplements do not prevent frailty in older adults

Immunotherapy before surgery improves outcomes in many patients with stage II–IV cutaneous squamous cell carcinoma

Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer

New software application predicts the likelihood of genetic mutation in dilated cardiomyopathy

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