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Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

Researchers performed a double-blinded, phase III randomized trial.

15 Jun 2023

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

Researchers used aerosolized receptor binding domain (RBD)-62 with 1,000-fold enhanced binding affinity.

15 Jun 2023

Vaccination against COVID-19 may consistently reduce the risk of long COVID symptoms

Researchers explored the efficacy of coronavirus disease 2019 (COVID-19) vaccines in preventing long COVID symptoms.

15 Jun 2023

Measuring the receipt of medications and behavioral health services for AUD

Heavy drinking commonly begins in adolescence and is a known risk factor for the development of alcohol use disorder (AUD). Data from adult clinical trials suggest offering evidence-based medications for AUD to younger adults could promote their engagement in treatment and improve clinical outcomes.

15 Jun 2023

Being "not up-to-date" on COVID-19 vaccination linked to lower risk of infection, study suggests

Researchers investigate whether not “up-to-date” individuals had a higher risk of COVID-19 than “up-to-date” individuals.

14 Jun 2023

Tea tree oil holds promise as a natural remedy for acne

The anti-acne properties of tea tree oil, which is widely known for its antibacterial, anti-inflammatory, and anti-oxidant properties.

14 Jun 2023

Breast cancer drug development work moves forward with support from STTR grant

Triple negative breast cancer is an aggressive subtype of breast cancer with worse survival outcomes than most.

14 Jun 2023

From delicacy to danger: The rising tide of shellfish allergies in children revealed

Shellfish consumption is on the rise, but so are shellfish allergies, particularly among children. A recent review delves into the epidemiology, symptoms, diagnosis, and management of shellfish allergies, highlighting the need for improved diagnostic tools and potential allergen immunotherapy.

13 Jun 2023

Berlin scientists further improve nasal vaccine against coronavirus

After having successfully tested a mucosal vaccine against coronavirus in animals just months ago, Berlin scientists have now further developed their live SARS-CoV-2 vaccine.

13 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Bamboo's hidden treasures: unveiling the possible health-boosting powers of leaf and sheath extracts

Researchers explored the antioxidant and anti-inflammatory properties of bamboo leaves and sheaths.

13 Jun 2023

AI model NYUTron shows remarkable accuracy in clinical tasks using handwritten physician notes

In a recent article published in the journal Nature, researchers used unstructured clinical notes from the electronic health record (EHRs) to train NYUTron, a large language model for medical language and subsequently evaluated its ability to perform five clinical and operational predictive tasks.

13 Jun 2023

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

In a recent article published in the journal JAMA Network, researchers performed a randomized clinical trial (RCT) to demonstrate the noninferiority of letermovir vs. valganciclovir for prophylaxis of cytomegalovirus (CMV) in adult CMV-seronegative kidney transplant recipients (KTRs) who received a kidney from a CMV-seropositive individual.

13 Jun 2023

Analyzing the role of LP-284 Hodgkin's lymphoma models and in DNA damage repair

A new research paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair."

13 Jun 2023

Metformin shows promising antiviral activity against SARS-CoV-2

Metformin, a widely available oral medication, reduces SARS-CoV-2 viral load by 3.6-fold in outpatient trial, offering a potential treatment option. Ivermectin and fluvoxamine show no significant virologic effect.

12 Jun 2023

VLA1553 vaccine candidate for chikungunya disease produces an immune response in a phase 3 trial

The VLA1553 vaccine candidate for chikungunya disease was generally well tolerated and produced an immune response in 99% (263/266) of participants, according to a phase 3 randomized controlled trial published in The Lancet.

12 Jun 2023

Study: Gentle cleansers just as effective as harsh soaps in killing viruses

Gentle cleansers are just as effective in killing viruses - including coronavirus - as harsh soaps, a new study by University of Sheffield experts has found.

11 Jun 2023

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

A human or animal's microbiome - the collection of often beneficial microorganisms, including as bacteria and fungi, that live on or within a host organism - can play an important role in the host's overall immune response, but it is unclear how vaccines against harmful pathogens impact the microbiome.

11 Jun 2023

Study validates vaccine effectiveness: COVID-19 shots cut hospitalization and mortality rates in England

A new study examines hospitalization and mortality rates from COVID-19 before and after the rollout of the vaccine in England.

11 Jun 2023

Disinfectants play vital role in infection control and prevention

Infection control stands as a cornerstone of modern healthcare systems, safeguarding patients, healthcare professionals, and the community at large.

10 Jun 2023

Efficacy News and Research

Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

A new weapon against COVID: RBD-62 protein shows promising results in preventing severe disease

Vaccination against COVID-19 may consistently reduce the risk of long COVID symptoms

Measuring the receipt of medications and behavioral health services for AUD

Being "not up-to-date" on COVID-19 vaccination linked to lower risk of infection, study suggests

Tea tree oil holds promise as a natural remedy for acne

Breast cancer drug development work moves forward with support from STTR grant

From delicacy to danger: The rising tide of shellfish allergies in children revealed

Berlin scientists further improve nasal vaccine against coronavirus

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Bamboo's hidden treasures: unveiling the possible health-boosting powers of leaf and sheath extracts

AI model NYUTron shows remarkable accuracy in clinical tasks using handwritten physician notes

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

Analyzing the role of LP-284 Hodgkin's lymphoma models and in DNA damage repair

Metformin shows promising antiviral activity against SARS-CoV-2

VLA1553 vaccine candidate for chikungunya disease produces an immune response in a phase 3 trial

Study: Gentle cleansers just as effective as harsh soaps in killing viruses

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

Study validates vaccine effectiveness: COVID-19 shots cut hospitalization and mortality rates in England

Disinfectants play vital role in infection control and prevention

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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