Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

A group of investigators from Mayo Clinic and multiple academic research centers in Italy have identified a genetic model for predicting outcomes in patients with primary myelofibrosis who are 70 years or younger and candidates for stem cell transplant to treat their disease.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

SLU scientists provide promising approach in designing new drugs for DMD

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD.

8 Dec 2017

3D mini brains put researchers on a fast track to repair the nervous system

The Houston Methodist Research Institute is making mini brains from human stem cells that put researchers on a fast track to repair the nervous system after injury or disease of the brain and spinal cord.

8 Dec 2017

Optogenetics research sheds new light on social-spatial learning

Ilana Witten didn't set out to study spatial learning. She thought she was investigating how mice socialize--but she discovered that in mouse brains, the social and the spatial are inextricably linked.

8 Dec 2017

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Multiple myeloma is the second most common blood cancer in the United States. Thirty to 50 percent of multiple myeloma patients have extra copies of the gene that encodes the enzyme ADAR1.

6 Dec 2017

Hyperbaric oxygen therapy can improve pathology of Alzheimer's disease, study shows

A new Tel Aviv University study reveals that hyperbaric oxygen treatments may ameliorate symptoms experienced by patients with Alzheimer's disease.

6 Dec 2017

Scientists develop multi-step method to harvest amniotic fluid

Amniotic fluid, the protective liquid surrounding an unborn baby, is discarded as medical waste during cesarean section deliveries.

6 Dec 2017

New mass-production platform overcomes barriers to bioengineering human liver tissues

Researchers report creating a biologically accurate mass-production platform that overcomes major barriers to bioengineering human liver tissues suitable for therapeutic transplant into people.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine unanimously approved yesterday two grants worth a total of almost $8 million to University of California San Diego School of Medicine researchers investigating novel stem cell-based treatments for acute myeloid leukemia or AML.

4 Dec 2017

Innovative nanoparticle-based approach to fight myocardial infarction

How can damaged cardiac tissue following a heart attack best be treated with replacement muscle cells? A research team under the supervision of the University of Bonn is now presenting an innovative method on mice: Muscle replacement cells, which are to take over the function of the damaged tissue, are loaded with magnetic nanoparticles.

1 Dec 2017

Study provides insights on mechanisms involved in tolerance after kidney transplantation

A new study provides insights on the mechanisms that allow an individual's immune system to accept, rather than reject, a donor kidney. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, point to markers that could be monitored to assess and track the health of organs following transplantation.

1 Dec 2017

Stem Cells News and Research

Further Reading

New genetic model identified for predicting outcomes in patients with primary myelofibrosis

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Two immunotherapy approaches for multiple myeloma show hope

SLU scientists provide promising approach in designing new drugs for DMD

3D mini brains put researchers on a fast track to repair the nervous system

Optogenetics research sheds new light on social-spatial learning

High ADAR1 enzyme levels correlate with reduced survival rates in multiple myeloma

Hyperbaric oxygen therapy can improve pathology of Alzheimer's disease, study shows

Scientists develop multi-step method to harvest amniotic fluid

New mass-production platform overcomes barriers to bioengineering human liver tissues

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

Innovative nanoparticle-based approach to fight myocardial infarction

Study provides insights on mechanisms involved in tolerance after kidney transplantation

Research suggests general mechanism by which dietary fats affect cellular physiology

Researchers identify vulnerability for glioblastoma subtypes

Molecule plays double role in maintaining gut health and promoting diseases

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Penn researchers reveal new approach to restart replication in cardiomyocytes after heart attack

Event guide: 7th Allogeneic Cell Therapies Summit eBook

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