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New study explores obecabtagene autoleucel for adults with hard-to-treat leukemia

FELIX study results reveal obe-cel's potential in relapsed B-cell ALL, achieving 77% remission with low severe toxicity, enhancing CAR T-cell therapy outcomes.

2 Dec 2024

Homebound seniors living alone often slip through health system’s cracks

Carolyn Dickens, 76, was sitting at her dining room table, struggling to catch her breath as her physician looked on with concern.

2 Dec 2024

Neural connectivity predicts deep brain stimulation success in essential tremor

Study unveils how specific cortico-thalamic connectivity patterns influence essential tremor suppression with deep brain stimulation (DBS). It highlights the contralateral thalamus as a pivotal driver of tremor modulation and potential pathways for enhanced intervention strategies.

1 Dec 2024

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Study highlights the safety and early bactericidal activity of quabodepistat when combined with delamanid, bedaquiline, or both, offering potential for shorter and more tolerable tuberculosis treatment regimens.

1 Dec 2024

Phase 1 study finds serine- and glycine-free diet boosts immune response in colorectal cancer

Findings indicate a serine/glycine-free diet can reduce colorectal cancer growth and enhance immune response, offering insights for immunotherapy strategies.

29 Nov 2024

Scientists identify drug-resistant bone marrow cells linked to poor outcomes in fast-growing leukemia

Researchers explore treatment resistance and relapse in T-cell acute lymphoblastic leukemia.

29 Nov 2024

STAG2 loss linked to increased aggression in Ewing sarcoma

Ewing sarcoma is a tumor of the bones and soft tissues that occurs in children and young people. Like all childhood cancers, it is rare – 9 to 10 cases per million inhabitants per year – but it is very aggressive. 25% of patients do not respond well to regular therapy and they often experience relapses.

29 Nov 2024

Research highlights long-term health effects of hormone therapy in transgender individuals

New research from Karolinska Institutet shows that long-term sex hormone treatment in transgender individuals can lead to significant changes in body composition and risk factors for cardiovascular disease, particularly in transgender men.

28 Nov 2024

Study reveals varied risks of hormone treatments for menopausal symptoms

Researchers at Uppsala University have analyzed the effects of seven different hormone treatments for menopausal symptoms on the risk of blood clots, stroke and heart attack.

28 Nov 2024

Specific HRT tablets linked to increased risk of heart disease and blood clots

Certain hormone replacement therapy (HRT) tablets containing both estrogen and progestogen are associated with a higher risk of heart disease and rare but serious blood clots known as venous thromboembolism (VTE) in women around the age of menopause, finds a study from Sweden published by The BMJ today.

28 Nov 2024

Obe-cel demonstrates strong efficacy and safety in treating leukemia

Patients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) who were treated with the novel anti-CD19 chimeric antigen receptor (CAR) T cell therapy, obecabtagene autoleucel (obe-cel), experienced high response rates and most did not need a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II FELIX trial co-led by researchers at The University of Texas MD Anderson Cancer Center.

27 Nov 2024

CBT and rehabilitation likely to improve long covid symptoms

Cognitive behavioral therapy (CBT) and a program of physical and mental rehabilitation probably improve symptoms of long covid, but the effects are modest, finds a review of the latest evidence published by The BMJ today.

27 Nov 2024

New injection treatment could be a game-changer for people with asthma and COPD

An injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%.

27 Nov 2024

SONIA trial demonstrates cost-effective treatment approach for advanced breast cancer

On November 27, the prestigious journal Nature will publish the results of an innovative breast cancer research project from the Netherlands.

27 Nov 2024

Understanding the pathophysiological relationship between OSA and metabolic syndrome

Cardiovascular diseases remain a leading cause of mortality globally, particularly among individuals with both obstructive sleep apnea (OSA) and metabolic syndrome (MetS).

27 Nov 2024

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a retinal detachment repair or traumatic injury to the eye.

27 Nov 2024

IQWiG evaluates smoking cessation drugs for severe tobacco dependence treatment

By law, smokers with severe tobacco dependence are entitled to receive one-off drug therapy for smoking cessation as part of evidence-based programmes reimbursed by the German statutory health insurance (SHI).

27 Nov 2024

New gold-based drug proves to be more potent than standard chemotherapy

A new gold-based drug can slow tumour growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to a study by Australian and Indian researchers.

27 Nov 2024

Individuals with less efficient learning mechanisms benefit more from brain stimulation

As we age, our cognitive and motor functions deteriorate, which in turn affects our independence and overall quality of life.

27 Nov 2024

Study links cell death pathway to cancer resistance and growth

A new study has uncovered an unexpected way cancer cells can escape the immune system, making it harder for treatments to work. The study, published in Cancer Cell, explains how a type of cancer cell death can actually make tumors grow faster by turning off the immune system's ability to fight the cancer.

27 Nov 2024

Therapy News and Research

New study explores obecabtagene autoleucel for adults with hard-to-treat leukemia

Homebound seniors living alone often slip through health system’s cracks

Neural connectivity predicts deep brain stimulation success in essential tremor

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Phase 1 study finds serine- and glycine-free diet boosts immune response in colorectal cancer

Scientists identify drug-resistant bone marrow cells linked to poor outcomes in fast-growing leukemia

STAG2 loss linked to increased aggression in Ewing sarcoma

Research highlights long-term health effects of hormone therapy in transgender individuals

Study reveals varied risks of hormone treatments for menopausal symptoms

Specific HRT tablets linked to increased risk of heart disease and blood clots

Obe-cel demonstrates strong efficacy and safety in treating leukemia

CBT and rehabilitation likely to improve long covid symptoms

New injection treatment could be a game-changer for people with asthma and COPD

SONIA trial demonstrates cost-effective treatment approach for advanced breast cancer

Understanding the pathophysiological relationship between OSA and metabolic syndrome

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

IQWiG evaluates smoking cessation drugs for severe tobacco dependence treatment

New gold-based drug proves to be more potent than standard chemotherapy

Individuals with less efficient learning mechanisms benefit more from brain stimulation

Study links cell death pathway to cancer resistance and growth

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