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Specific blood test could indicate neoadjuvant treatment regimens for ESCC patients

A blood test may be beneficial in indicating neoadjuvant treatment regimens for patients with esophageal squamous cell carcinoma (ESCC), according to research presented today at the American Society for Radiation Oncology's 56th Annual Meeting.

16 Sep 2014

Thoracic radiotherapy reduces cancer recurrence in SCLC patients, shows new study

Treating advanced small-cell lung cancer (SCLC) with thoracic (or chest) radiation therapy in addition to standard treatment significantly prolongs long-term survival and reduces cancer recurrence in the chest by almost 50%, according to new research published in The Lancet and being presented simultaneously at ASTRO's 2014 Annual Meeting in San Francisco.

16 Sep 2014

Leaky intestines may cripple bacteria-fighting immune cells in patients with CVID

Leaky intestines may cripple bacteria-fighting immune cells in patients with a rare hereditary disease, according to a study by researchers in Lausanne, Switzerland. The study, published in The Journal of Experimental Medicine, may explain why these patients suffer from recurrent bacterial infections.

16 Sep 2014

Researchers uncover new pathways that transport sugar molecules to cells

Sugar is a vital source of energy for both plants and animals alike. Understanding just how sugar makes its way into the cell could lead to the design of better drugs for diabetes patients and an increase in the amount of fruits and vegetables farmers are able to grow.

16 Sep 2014

New ACD European subsidiary aims to provide faster, enhanced support for local customers

Advanced Cell Diagnostics Inc., a technology and market leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced the establishment of a European subsidiary which will start business in October 2014.

From Advanced Cell Diagnostics 16 Sep 2014

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Iron is a key nutrient for nearly all living organisms, including bacteria. Iron is a cofactor for many enzymes necessary for basic metabolic reactions such as DNA synthesis and electron transport. Iron serves as the conduit for the electron transport chain that generates the energy necessary to drive the bacterial cell.

16 Sep 2014

Collaborative study takes important step toward finding targeted treatments for bladder cancer

The story of cancer care seems so simple: find the mutated gene that causes cancer and turn it off or fix it. But rarely does a single gene cause cancer. More often, many genes are altered together to drive the disease. So the challenge becomes sorting out which altered genes are the most to blame in which cancers.

16 Sep 2014

Patients with particular genetic variation more prone to drug-induced pancreatitis

Doctors have discovered that patients with a particular genetic variation are four times more likely to develop pancreatitis if they are prescribed a widely used group of drugs.

16 Sep 2014

Amgen announces phase 3 ivabradine data for treatment of chronic HF

Amgen (NASDAQ: AMGN) today announced data from the Phase 3 SHIFT (Systolic Heart failure treatment with the If inhibitor ivabradine Trial) study evaluating ivabradine in patients with chronic heart failure (HF) were presented at the 18th Annual Scientific Meeting of the Heart Failure Society of America (HFSA) in Las Vegas.

15 Sep 2014

Six research institutions awarded NIH grants to create database of human cellular responses

Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses, the Library of Integrated Network-based Cellular Signatures.

15 Sep 2014

Simple point-of-care testing device provides more rapid diagnosis of anemia

A simple point-of-care testing device for anemia could provide more rapid diagnosis of the common blood disorder and allow inexpensive at-home self-monitoring of persons with chronic forms of the disease.

15 Sep 2014

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Using a zebrafish model of a human genetic disease called neurofibromatosis (NF1), a team from the Perelman School of Medicine at the University of Pennsylvania has found that the learning and memory components of the disorder are distinct features that will likely need different treatment approaches.

15 Sep 2014

Researchers report that dendritic cells can affect psoriasis

Different types of dendritic cells in human skin have assorted functions in the early and more advanced stages of psoriasis report researchers in the journal EMBO Molecular Medicine.

15 Sep 2014

UC Irvine study sheds light on cognitive losses

Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to UC Irvine neuroscientists Jennifer Czerniawski and John Guzowski.

15 Sep 2014

New class of compounds protect brain cells from traumatic brain injury

A new class of compounds has now been shown to protect brain cells from the type of damage caused by blast-mediated traumatic brain injury (TBI).

12 Sep 2014

Human stem cells can be reset to their native undifferentiated state

Scientists at the Babraham Institute, in collaboration with colleagues at the Cambridge Stem Cell Institute and the European Bioinformatics Institute, have made a breakthrough in stem cell research. Their paper, published today in Cell, describes how human stem cells can be reverted back to non-specialised cells.

11 Sep 2014

ChromaDex signs NIAGEN supply agreement with Healthy Directions

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, cosmetic and pharmaceutical industries, announced today that it has entered into an ingredient supply agreement with Healthy Directions, a direct-to-consumer nutritional supplement retailer and wholly-owned subsidiary of Helen of Troy Limited.

11 Sep 2014

AstraZeneca is developing new PARP inhibitor for treatment of ovarian cancer

The ovarian cancer market is highly active with several promising candidates having reached the late stages of development. Three PARP inhibitors, Lynparza (AstraZeneca), niraparib (Tesaro) and rucaparib (Clovis Oncology), which induce cell death in mutated [BRCA-deficient] cancer cells, have been identified by Datamonitor Healthcare as front runners.

11 Sep 2014

Researchers discover new details of how autoantibodies destroy healthy cells in skin

University at Buffalo researchers and colleagues studying a rare, blistering disease have discovered new details of how autoantibodies destroy healthy cells in skin.

11 Sep 2014

Gastroenterologist hopes to achieve healthy growth and development in children around the world

Why is it harder for kids in low- and middle-income countries to grow as well as kids in wealthy countries? Food security, or access to good nutrition, remains a major challenge. The issue is not just food supply but poor sanitation - a problem exacerbated by local infrastructure and cultural mores.

11 Sep 2014

B Cell News and Research

Specific blood test could indicate neoadjuvant treatment regimens for ESCC patients

Thoracic radiotherapy reduces cancer recurrence in SCLC patients, shows new study

Leaky intestines may cripple bacteria-fighting immune cells in patients with CVID

Researchers uncover new pathways that transport sugar molecules to cells

New ACD European subsidiary aims to provide faster, enhanced support for local customers

Blocking bacteria's access to iron: an interview with Dr. Laxminarayana Devireddy

Collaborative study takes important step toward finding targeted treatments for bladder cancer

Patients with particular genetic variation more prone to drug-induced pancreatitis

Amgen announces phase 3 ivabradine data for treatment of chronic HF

Six research institutions awarded NIH grants to create database of human cellular responses

Simple point-of-care testing device provides more rapid diagnosis of anemia

Researchers find learning and memory components of neurofibromatosis using zebrafish model

Researchers report that dendritic cells can affect psoriasis

UC Irvine study sheds light on cognitive losses

New class of compounds protect brain cells from traumatic brain injury

Human stem cells can be reset to their native undifferentiated state

ChromaDex signs NIAGEN supply agreement with Healthy Directions

AstraZeneca is developing new PARP inhibitor for treatment of ovarian cancer

Researchers discover new details of how autoantibodies destroy healthy cells in skin

Gastroenterologist hopes to achieve healthy growth and development in children around the world

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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