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Weight loss with ozempic may weaken muscles even when size remains stable

As use of the popular anti-diabetic and weight-loss drug Ozempic skyrockets, so have concerns about the medication's side effects.

5 Aug 2025

KAIST scientists achieve first total synthesis of herpotrichone with neuroprotective properties

"Herpotrichone" is a natural substance that has been evaluated highly for its excellent ability to suppress inflammation in the brain and protect nerve cells, displaying significant potential to be developed as a therapeutic agent for neurodegenerative brain diseases such as Alzheimer's disease and Parkinson's disease.

5 Aug 2025

PDGFRA+ progenitors identified as key players in angiogenesis and periodontal tissue repair

Stem cell research, alongside the rapidly advancing field of biotechnology, has led to remarkable innovations in regenerative medicine.

5 Aug 2025

Scaling organ‑chip technology for human‑relevant drug discovery

Discover how AVA brings scale and reproducibility to organ‑chip technology, enabling human‑relevant insights that accelerate drug discovery workflows.

From Emulate, Inc. 5 Aug 2025

AI model advances prediction of microsatellite status in cancer

One in every three people is expected to have cancer in their lifetime, making it a major health concern for mankind.

5 Aug 2025

Breakthrough study reveals potential treatment path for ALS

Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig's disease, is an incurable neurological disorder affecting motor neurons-nerve cells in the brain and spinal cord that control voluntary muscle movement and breathing.

5 Aug 2025

Gfi1 regulates exhausted CD8+ T cells to improve cancer immunotherapy

Killer immune cells destroy cancer cells and cells infected by virus. These CD8+ T cells are activated after detection of viral infection or growth of "non-self" tumor cells.

5 Aug 2025

Cannabis use disorder triples five-year risk of oral cancer

Research shows cannabis use disorder triples the risk of oral cancer, challenging perceptions of cannabis safety and prompting calls for health screenings.

5 Aug 2025

LptM protein revealed as essential to outer membrane stability in bacteria

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria.

4 Aug 2025

'Two-in-one' RNA molecule can simultaneously turn off two difficult-to-target cancer-related genes

University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that can simultaneously turn off two notoriously difficult-to-target cancer-related genes, KRAS and MYC, as well as directly deliver drugs to tumors that express these genes.

4 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

New insights reveal how sugar metabolism protects neurons from degeneration

Unlike most cells in the human body, neurons-the functional cells of our nervous system-cannot typically replace themselves with healthy copies after being damaged.

4 Aug 2025

Natural brain rhythms control stress hormone levels and alertness

Ōtākou Whakaihu Waka-led research has found stress-controlling brain cells switch on and off in a steady rhythm about once every hour – even when nothing stressful is happening.

4 Aug 2025

Scientists reveal how rare gene mutations drive schizophrenia risk

Researchers analyzed the largest exome-sequencing dataset to date and identified new rare coding variants and genes linked to schizophrenia risk. The study highlights converging genetic pathways, implicating chromatin organization and GABAergic signaling in schizophrenia neurobiology.

4 Aug 2025

UCLA study shows stem cells can be reprogrammed to fight cancer

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents.

4 Aug 2025

Programmable Chromosome Engineering systems enable precise DNA manipulations

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

4 Aug 2025