Immune System News and Research

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Study sheds new light on how the B cell academy mounts a diverse immune response

Cells jostling for a spot in a germinal center face a cutthroat admissions process. Formed after exposure to a pathogen or vaccine, germinal centers act as a kind of immune system training academy, helping B cells refine their response to the threat.

18 Jan 2023

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Mice exposed to World Trade Center dust exhibit a significant impairment in spatial recognition and short- and long-term memory, as well as changes in genes related to immune-inflammatory responses and blood-brain barrier disruption, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai and published January 17 in the Journal of Alzheimer's Disease.

17 Jan 2023

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

A promising approach to control Staphylococcus aureus bacterial colonization in people - using a probiotic instead of antibiotics - was safe and highly effective in a Phase 2 clinical trial.

17 Jan 2023

Green living environments affect the composition of oligosaccharides in breastmilk

A new study conducted at the University of Turku, Finland, examined the association between the residential green environment and the individual oligosaccharide profile in the mother's breastmilk.

17 Jan 2023

S. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein A

Researchers assessed the impact of Staphylococcus aureus (S. aureus) on SARS-CoV-2 replication.

17 Jan 2023

Could drinking tea help manage COVID-19?

Researchers summarized the content of active ingredients in different types of tea, the second most consumed beverage in the world. They also explored the possibility of using tea extracts for coronavirus disease 2019 (COVID-19) prevention and treatment.

17 Jan 2023

Study finds non-Omicron breakthrough infections elicit robust cross-neutralizing activity against Omicron variants across the antigenic barrier

Researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with a non-Omicron variant on SARS-CoV-2 BA.4/5 neutralization.

17 Jan 2023

Childhood asthma risk appears to be influenced by both the intestinal microbiome and 17q12-21 genotype

Childhood asthma is a condition that may be affected by different types of factors. These include the state of the infant's gut microbiome, environmental factors, and genetic factors. A recent study attempted to shed more light on how asthma risk is linked to a combination of these factors, some of which are modifiable.

16 Jan 2023

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

Researchers investigated how age-related T-cell defects impacted the effectiveness of mRNA-based COVID-19 vaccines.

16 Jan 2023

Targeting T cell iron metabolism may offer a new approach for treating lupus

Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) - the most common form of the chronic autoimmune disease lupus.

13 Jan 2023

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution.

13 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

What are the present challenges and future considerations in developing vaccines against mucosal respiratory viruses?

In a recent review, the former director of the National Institute of Allergy and Infectious Diseases and former chief medical advisor to the president of the United States (U.S.), Dr. Fauci, and his team review the roadblocks to developing effective vaccines against viruses that infect the human respiratory mucosa and discuss strategies for next-generation vaccine development against mucosal respiratory viruses

13 Jan 2023

New drug combination may offer better prognosis for children diagnosed with deadly brain cancer

Researchers at the University of Colorado Anschutz Medical Campus have discovered a drug combination that may offer a better prognosis for children diagnosed with MYC amplified Medulloblastoma, an often deadly form of brain cancer.

13 Jan 2023

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Researchers reviewed the impact of the interactions between the respiratory microbiota and the immune system.

13 Jan 2023

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Scientists from The Australian National University and the Peter MacCallum Cancer Centre have discovered that a protein, called Menin, contributes to abnormal deactivation of specific genes in cancer cells.

13 Jan 2023

American Cancer Society's annual report on cancer facts and trends released

Today, the American Cancer Society released Cancer Statistics, 2023, the organization's annual report on cancer facts and trends. According to the report, overall cancer mortality has dropped 33% since 1991, averting an estimated 3.8 million cancer deaths.

12 Jan 2023

Immune System News and Research

Study sheds new light on how the B cell academy mounts a diverse immune response

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

Green living environments affect the composition of oligosaccharides in breastmilk

S. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein A

Could drinking tea help manage COVID-19?

Study finds non-Omicron breakthrough infections elicit robust cross-neutralizing activity against Omicron variants across the antigenic barrier

Childhood asthma risk appears to be influenced by both the intestinal microbiome and 17q12-21 genotype

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

Targeting T cell iron metabolism may offer a new approach for treating lupus

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Valuable tool reveals the connections between gut microbes and the brain

What are the present challenges and future considerations in developing vaccines against mucosal respiratory viruses?

New drug combination may offer better prognosis for children diagnosed with deadly brain cancer

The impact of early life microbial colonization and respiratory diseases on the respiratory microbiome

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

American Cancer Society's annual report on cancer facts and trends released

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

LJI scientists uncover how OGT enzyme keeps cells healthy

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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