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Researchers explore the role of trigeminal axons in nose-to-brain delivery of antidepressant

Intranasal (in.) administration has been garnering increasing popularity as a non-invasive approach to deliver drugs directly to the brain. This approach involves the respiratory or olfactory epithelia of the nasal mucosa through which the drugs reach the central nervous system (CNS).

11 Nov 2022

Alterations in vaginal microbiota among pregnant women with COVID-19 increase preterm birth risk

A new study conducted by researchers from Koç University İsbank Center for Infectious Diseases (KUISCID) reveals crucial data on the risk of preterm birth caused by the change in vaginal microbiota due to COVID 19.

11 Nov 2022

Researchers discover new antiviral compounds derived from two Korean native plants

Codonopsis lanceolata, more commonly referred to as "deodeok", is used as a medicinal herb in South Korea.

11 Nov 2022

What is the duration of persistent symptoms after SARS-CoV-2 infection, and what factors are associated with their resolution?

Researchers examined temporal dynamics of persistent symptom resolution following acute COVID-19 in the general population of France.

11 Nov 2022

Is placental antibody transfer after COVID-19 vaccination different from that after SARS-CoV-2 infection in pregnant individuals?

Researchers investigated the placental transfer ratios of anti-SARS-CoV-2 antibodies in pregnant females.

11 Nov 2022

Analysis reveals highest number of pneumonia deaths in the UK

More people die from pneumonia in the UK than anywhere else in Europe, according to new analysis by leading lung charity, Asthma + Lung UK. Now, the charity is raising awareness of the signs and symptoms of pneumonia, and urging people who are eligible, such as those with severe asthma, pulmonary fibrosis and COPD, to get their one-off pneumonia vaccine.

10 Nov 2022

Surge in RSV cases – how worried should you be?

RSV hospitalizations are reaching similarly high levels much earlier than normal this year.

10 Nov 2022

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

An article published in the journal PNAS provides a conceptual analysis to interpret the brain state of coronavirus disease 2019 (COVID-19) patients experiencing prolonged recovery of consciousness.

10 Nov 2022

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

In a recent study under review at the Nature Portfolio journal and currently posted to Research Square* preprint server, researchers developed and assessed the immunogenicity of nanoparticles expressing spike trimers from coronaviruses (CoVs).

10 Nov 2022

A knowledgebase of currently known categorized COVID-19 severity variants

In a recent study posted to the medRxiv* preprint server, researchers assessed human genome variants related to the susceptibility and severity of coronavirus disease 2019 (COVID-19).

10 Nov 2022

Global SARS-CoV-2 infection rates likely to be higher than previously reported

Serosurveillance provides estimates of antibody levels against infectious diseases and is considered the gold standard for measuring population immunity due to past infection or vaccination.

10 Nov 2022

Anaphylaxis symptoms in most infants appear to resolve with a single dose of epinephrine

Although many parents of infants worry about their child having a food allergy, there has not been a lot of research into the presentation of anaphylaxis in infants.

10 Nov 2022

How did alcohol consumption change during the COVID-19 pandemic in the state of Wisconsin?

Researchers evaluated the patterns of alcohol use at three different time points during the SARS-CoV-2 pandemic in Wisconsin.

10 Nov 2022

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

Researchers investigated the neutralization antibody titers and the efficacy of the humoral and cellular immunities in individuals vaccinated with three COVID-19 vaccines.

10 Nov 2022

The spectrum of SARS-CoV-2–related neurologic involvement among children and adolescents in 2021

Researchers explored the distribution of severe neurologic involvement in SARS-CoV-2 pediatric patients.

10 Nov 2022

Melatonin could be a potential therapy for long-COVID symptoms

A recent review published in the journal Biomolecules discussed the potential uses of melatonin in treating brain fog, and chronic fatigue syndrome or myalgic encephalomyelitis symptoms associated with long coronavirus disease (COVID)

9 Nov 2022

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

In a recent study posted to the Research Square* preprint server and under review at the Nature Portfolio journal, researchers reported activation and maturation of antigen-presenting cells (APCs) by lipid nanoparticles (LNPs).

9 Nov 2022

Coronavirus exposure reduction strategies in aircraft cabins involving vacant middle seats and masks

In a recent study published in the journal Engineering Reports, researchers evaluated the reduction in exposure to airborne viruses in aircraft cabins when mitigation measures such as mask-wearing and leaving the middle seat vacant were adopted to understand strategies to limit the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during air travel.

9 Nov 2022

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

Researchers used a deep antibody-antigen interaction (DeepAAI) algorithm to understand the antibody representations of unseen antibodies to accelerate the discovery of novel antibodies with potential therapeutic applications.

9 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

Respiratory News and Research

Researchers explore the role of trigeminal axons in nose-to-brain delivery of antidepressant

Alterations in vaginal microbiota among pregnant women with COVID-19 increase preterm birth risk

Researchers discover new antiviral compounds derived from two Korean native plants

What is the duration of persistent symptoms after SARS-CoV-2 infection, and what factors are associated with their resolution?

Is placental antibody transfer after COVID-19 vaccination different from that after SARS-CoV-2 infection in pregnant individuals?

Analysis reveals highest number of pneumonia deaths in the UK

Surge in RSV cases – how worried should you be?

Delay in consciousness in severe cases of COVID-19 may be caused by neural hibernation

Mosaic nanoparticles displaying spike protein trimers from different coronaviruses elicits cross-reactive protection

A knowledgebase of currently known categorized COVID-19 severity variants

Global SARS-CoV-2 infection rates likely to be higher than previously reported

Anaphylaxis symptoms in most infants appear to resolve with a single dose of epinephrine

How did alcohol consumption change during the COVID-19 pandemic in the state of Wisconsin?

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

The spectrum of SARS-CoV-2–related neurologic involvement among children and adolescents in 2021

Melatonin could be a potential therapy for long-COVID symptoms

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

Coronavirus exposure reduction strategies in aircraft cabins involving vacant middle seats and masks

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

What is the role of adenoviruses in human health?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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