Genes News and Research

RSS

RNA-seq analysis reveals key factors in intervertebral disc degeneration

In a rapid communication published in the journal Genes & Diseases, researchers from Chongqing Medical University and Yongchuan Traditional Chinese Medicine Hospital of Chongqing have unveiled crucial insights into the factors that might influence Intervertebral Disc Degeneration (IDD).

15 Dec 2023

New methodology may be important in the fight against antimicrobial resistance

NTNU has developed a promising antibiotic candidate against MRSA. Behind the discovery lies a methodology that may be important in the fight against antimicrobial resistance.

15 Dec 2023

Waseda researchers unravel secrets of building better brain organoids with blood vessels

Researchers at Waseda University led by Assistant Professor Kosuke Kataoka, have uncovered crucial insights into brain organoids’ development.

15 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

Alzheimer's may worsen COVID-19 outcomes via olfactory mucosa changes

A new study identifies alterations in the transcriptomic signatures in human olfactory mucosal cells of individuals with Alzheimer's disease following SARS-CoV-2 infection, potentially contributing to exacerbated COVID-19 outcomes.

15 Dec 2023

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

A new LMU-led DFG Research Unit is developing innovative approaches for treating retinal diseases.

15 Dec 2023

Study uncovers vast genomic diversity in Aboriginal Australian communities

Study on Aboriginal Australian communities using whole-genome sequencing reveals a high level of unique genetic diversity, including novel alleles and structural variants, crucial for understanding human genomic evolution and medical genetics.

14 Dec 2023

Research shows how the immune system keeps Herpes simplex virus at bay

Herpes simplex virus (HSV) is extremely common, affecting nearly two-thirds of the world's population, according to the World Health Organization.

14 Dec 2023

Unlocking the secrets of our "dark genome": Scientists crack the code of LINE-1

A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome" - the 98 percent of our DNA that has largely unknown biological function.

14 Dec 2023

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

The role of type-2 interferon (IFNγ) in antiviral immunity.

14 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

CRISPR opens doors for novel probiotic functions and applications

Humans can benefit significantly from symbiotic relationships with probiotics - live bacteria and microorganisms that influence the gut microbiota.

13 Dec 2023

$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments

With an estimated 1.9 million new cases and more than 600,000 deaths each year, cancer remains the second most common cause of death in the U.S., trailing only heart disease. And while there are more than 200 types of cancer, the abnormal synthesis of a protein known as STAT3 is unique to the majority of tumors.

13 Dec 2023

Understanding why cutting-edge cell therapies cause an increased risk of heart rhythm disorders

A type of cell that plays a crucial role in tissue repair after a heart attack may also inadvertently be why cutting-edge cell therapies cause an increased risk of rhythm disorders, according to a new study from the Universities of Surrey and Oxford.

13 Dec 2023

Epigenetic changes can contribute to the development of type 2 diabetes

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.

13 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Immunopeptidomics offer new hope in cancer research

In this new omg OMx podcast episode, Bruker's Kate Stumpo speaks to Nicola Ternette on the incredible world of immunopeptidomics - the implications they could have for research and how they help us understand the immune system better.

From Bruker Daltonics 13 Dec 2023

Tat-heat shock protein 10 could rejuvenate aging brains

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, "Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampus."

12 Dec 2023

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis.

12 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023