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Northwestern scientists continue to advance the understanding of COVID-19

As the COVID-19 pandemic enters its third year, Northwestern Medicine scientists continue to help advance the understanding of the disease and its impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research and highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.

28 Mar 2022

Study investigates recombinant SARS-CoV-2 variants in immunocompromised individuals

Researchers identified the recombination of two SARS-CoV-2 variants.

28 Mar 2022

Study estimates protection against reinfection following primary SARS-CoV-2 infection

A recent study investigated the protection provided by the primary SARS-CoV-2 infection against reinfection.

28 Mar 2022

Severe outcomes in hospitalized children during the Omicron BA.2-dominated fifth wave in Hong Kong

A recent study investigated the disease severity of SARS-CoV-2 Omicron BA.2 infection among Hong Kong children.

28 Mar 2022

CDK6: a potential drug target for severe COVID-19

Researchers identify a methodology and workflow to repurpose drugs against the cyclin-dependent kinase 6 target gene of SARS-CoV-2.

27 Mar 2022

U.S. traveler-based genomic surveillance provided early SARS-CoV-2 variant detection

Researchers discuss their efforts to detect SARS-CoV-2 and its variants in travelers entering the United States.

27 Mar 2022

Biologists discover gene deletion behind abnormality in blood cancer cells

The mystery is being unraveled of why the control centers, or nuclei, of certain blood cancer cells have a distinctly odd shape.

27 Mar 2022

Researchers discover new pathway for DNA transfer in tumor microenvironment

University of Notre Dame researchers have discovered another way tumor cells transfer genetic material to other cells in their microenvironment, causing cancer to spread.

25 Mar 2022

Study explores macrophage susceptibility to SARS-CoV-2 virions

A new study investigated the susceptibility of macrophages to SARS-CoV-2 virions.

25 Mar 2022

Study evaluates the clinical accuracy of two FDA-approved rapid antigen tests across SARS-CoV-2 variants

Researchers evaluated clinical accuracy and analytical detection capabilities of the two US Food and Drug Administration-approved rapid antigen tests across SARS-CoV-2 variants.

25 Mar 2022

Understanding a New Mutation in Pediatric AML

News-Medical speaks to Dr. Jeffery Klco about acute myeloid leukemia (AML) and his recent research that is helping us to understand a new mutation in pediatric AML.

25 Mar 2022

The intercontinental spread of high-pathogenic avian influenza A (H5N1) virus

Researchers aim to better understand the landscape movement of the avian influenza virus.

24 Mar 2022

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

A new study evaluated the N terminal domain of the SARS-CoV-2 nucleocapsid protein. It presented the targeted characteristics for selective ribonucleic acid identification by SARS-CoV-2 N in its 5'-genomic end.

24 Mar 2022

New SARS-CoV-2 Omicron-Delta recombinant virus identified in the US

Researchers reported a novel SARS-CoV-2 Omicron and Delta recombinant virus in the United States.

24 Mar 2022

Study elucidates importation risks and disproportionate spread of SARS-CoV-2 variants of concern in the Netherlands

Researchers used whole-genome sequencing to explore the transmission dynamics of four SARS-CoV-2 variants of concern - Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2) in the Netherlands.

24 Mar 2022

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

A recent study assessed the role of the SARS-CoV-2 Omicron spike H655Y mutation on viral entry pathways.

24 Mar 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

Study uncovers a gene that strongly associates with breast cancer patient's treatment outcomes

A multidisciplinary team of researchers from Roswell Park Comprehensive Cancer Center and Kaiser Permanente Northern California have identified the first pharmacogenomic marker for anthracyclines and HER2-targeting drugs, two commonly used breast cancer chemotherapies.

23 Mar 2022

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Scientists from the United States have recently assessed the evolutionary success of mutations accumulated across severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. They have observed that the positively-selected mutations in the viral spike S1 subunit are primarily responsible for adaptive evolution. This indicates that the virus may undergo antigenic drift.

23 Mar 2022

Predicting the risk of some common diseases in preimplantation fertilized embryos

A new study uses a novel strategy for whole-genome reconstruction by using parental genome sequencing and sibling embryo genotyping.

23 Mar 2022

Genome News and Research

Northwestern scientists continue to advance the understanding of COVID-19

Study investigates recombinant SARS-CoV-2 variants in immunocompromised individuals

Study estimates protection against reinfection following primary SARS-CoV-2 infection

Severe outcomes in hospitalized children during the Omicron BA.2-dominated fifth wave in Hong Kong

CDK6: a potential drug target for severe COVID-19

U.S. traveler-based genomic surveillance provided early SARS-CoV-2 variant detection

Biologists discover gene deletion behind abnormality in blood cancer cells

Researchers discover new pathway for DNA transfer in tumor microenvironment

Study explores macrophage susceptibility to SARS-CoV-2 virions

Study evaluates the clinical accuracy of two FDA-approved rapid antigen tests across SARS-CoV-2 variants

Understanding a New Mutation in Pediatric AML

The intercontinental spread of high-pathogenic avian influenza A (H5N1) virus

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

New SARS-CoV-2 Omicron-Delta recombinant virus identified in the US

Study elucidates importation risks and disproportionate spread of SARS-CoV-2 variants of concern in the Netherlands

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

Study uncovers a gene that strongly associates with breast cancer patient's treatment outcomes

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Predicting the risk of some common diseases in preimplantation fertilized embryos

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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