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Simple laser irradiation speeds up the detection of very small amounts of proteins

Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.

22 Dec 2022

Research sheds light on how mRNA boosters affect the durability of antibodies to COVID-19

New research from the University of Virginia School of Medicine speaks to the benefits of a COVID-19 booster.

22 Dec 2022

Cystic fibrosis drug shows promise to treat pneumonia

Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome.

22 Dec 2022

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.

22 Dec 2022

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome - a rare genetic, neurocognitive disorder.

22 Dec 2022

Research serves as a platform to identify therapeutic drugs for schizophrenia

Inflammation and overactivation of the immune system in the brain can cause loss of synapses and the death of neurons, leading to neurodegenerative and psychiatric diseases.

22 Dec 2022

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

22 Dec 2022

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia.

22 Dec 2022

Partial knee arthroplasty yields faster functional recovery than total knee replacement

For selected patients with knee osteoarthritis, unicompartmental (or "partial") knee arthroplasty (UKA) shortens the recovery time for two key measures of physical function, as compared with total knee arthroplasty (TKA), reports a randomized trial in The Journal of Bone & Joint Surgery.

22 Dec 2022

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.

22 Dec 2022

Extracellular vesicles enhance cancer immunotherapy

Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumors sensitive to a type of immunotherapy drug called a checkpoint inhibitor.

22 Dec 2022

Study provides valuable knowledge about physical fitness disparities among demographic groups

Sedentary behavior, a large waist circumference, and advanced age: These factors are clearly associated with inferior physical fitness among people aged 50 to 64.

22 Dec 2022

Study could pave the way for new drug to treat hand osteoarthritis

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

22 Dec 2022

3D neutron tomography reveals water diffusion across the bone material

What keeps bones able to remodel themselves and stay healthy? A team from Charité Berlin has discovered clues to the key function of non-collagen protein compounds and how they help bone cells react to external load.

22 Dec 2022

KHN’s ‘What the Health?’: The covid response coordinator speaks

Dr. Ashish Jha, the White House covid-19 response coordinator, is the guest for a wide-ranging interview on this week's "What the Health?" podcast.

22 Dec 2022

Botox treatment may lessen anxiety

Botox, or Botulinum toxin, a medication derived from a bacterial toxin, is commonly injected to ease wrinkles, migraines, muscle spasms, excessive sweating and incontinence.

22 Dec 2022

Adults could achieve physical activity targets by walking “Teabag style” for a few minutes each day

Adults could achieve global physical activity targets by walking inefficiently for just a few minutes each day, finds a study in the Christmas issue of The BMJ.

22 Dec 2022

Elite male football players who played in the 1960s and later have lower risk of alcohol disorders

Elite male football players have a lower risk of alcohol and drug related disorders than men from the general population, but this protective effect was seen only for those who first played in the 1960s and later, not for players from earlier eras, finds a study in the Christmas issue of The BMJ.

22 Dec 2022

Impact of epigenetics on the clinical management of cancer patients

Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments.

22 Dec 2022

‘Caged … for no fault of your own’: Detainees dread covid while awaiting immigration hearings

In October, Yibran Ramirez-Cecena didn't alert the staff at Stewart Detention Center to his cough and runny nose.

22 Dec 2022

Research News and Research

Simple laser irradiation speeds up the detection of very small amounts of proteins

Research sheds light on how mRNA boosters affect the durability of antibodies to COVID-19

Cystic fibrosis drug shows promise to treat pneumonia

NIH scientists use patient stem cells and 3D bioprinting to produce eye tissue

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

Research serves as a platform to identify therapeutic drugs for schizophrenia

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

Partial knee arthroplasty yields faster functional recovery than total knee replacement

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

Extracellular vesicles enhance cancer immunotherapy

Study provides valuable knowledge about physical fitness disparities among demographic groups

Study could pave the way for new drug to treat hand osteoarthritis

3D neutron tomography reveals water diffusion across the bone material

KHN’s ‘What the Health?’: The covid response coordinator speaks

Botox treatment may lessen anxiety

Adults could achieve physical activity targets by walking “Teabag style” for a few minutes each day

Elite male football players who played in the 1960s and later have lower risk of alcohol disorders

Impact of epigenetics on the clinical management of cancer patients

‘Caged … for no fault of your own’: Detainees dread covid while awaiting immigration hearings

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