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CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018

Interval of time to biochemical failure could be used as surrogate endpoint for prostate cancer

An analysis of the NRG Oncology clinical trial NRG-RTOG 9202 showed that the interval of time to biochemical failure, or the time it takes for previously treated cancer to return as indicated by prostate specific antigen rise, could be used as a surrogate endpoint for locally advanced prostate cancer.

21 Dec 2018

DHEA therapy may help prevent bone loss and increase muscle mass in older women

Women 55 and older have an increased risk of bone and muscle loss but therapy with the hormone Dehydroepiandrosterone may help prevent bone loss and increase muscle mass in older women, according to a new study led by Catherine M. Jankowski, PhD, FACSM, an exercise physiologist and associate professor at the University of Colorado College of Nursing at the Anschutz Medical Campus.

5 Dec 2018

Survey shows negative effect of vulvovaginal atrophy symptoms on quality of life for women

With symptoms such as dryness, burning, or itching of the vagina, vulvovaginal atrophy is estimated to affect up to 98% of postmenopausal women, many of whom will fail to report symptoms to their healthcare providers or seek help.

14 Nov 2018

Study defines biomarker in response to treatment of castration-resistant prostate cancer

The most aggressive type of prostate cancer, castration-resistant prostate cancer, can be treated with two different therapies: taxanes or hormone treatment. Until this day there are no comparative studies between the two and the decision on which treatment to use is done empirically and based on the patient's preferences.

14 Nov 2018

Prostate cancer patients receiving androgen deprivation therapy may have higher heart failure risk

Androgen deprivation therapy was associated with a 72 percent higher risk of heart failure in a study of patients with prostate cancer.

7 Nov 2018

New type of molecule shows early promise against treatment-resistant prostate cancer

A new type of molecule blocks the action of genes that drive the growth of therapy-resistant prostate cancer, a new study finds.

23 Oct 2018

Radiotherapy combined with androgen-deprivation therapy improves overall survival up to 10 years

The long-term follow up of the NRG Oncology trial RTOG 9408, studying the addition of short-term androgen-deprivation therapy (ADT) to radiotherapy (RT) for men with early, localized prostate adenocarcinoma, indicated that RT combined with ADT is superior to RT alone for overall survival up to 10.4 years following treatment.

23 Oct 2018

Prostate radiotherapy improves survival in men with low burden of metastatic disease

Radiotherapy to the prostate improves overall survival in men newly diagnosed with metastatic prostate cancer who have a low metastatic disease burden but not in those with higher burden of disease, according to results from a pre-planned analysis of a large comparison study reported at ESMO 2018.

22 Oct 2018

Researchers find ALS drug as potential treatment for prostate cancer

Researchers have discovered a new use for an old drug as a potential treatment for prostate cancer. The findings are published in the journal The Prostate.

3 Oct 2018

Prostatectomy plus radiotherapy associated with greater survival in prostate cancer patients

High-risk prostate cancer, that which has continued to grow but not yet metastasized, is commonly treated with combination therapies. Each method has pros and cons, but there is little clarity whether one might be more effective than the other.

25 Sep 2018

Research team identifies new therapeutic target for castration-resistant prostate cancer

A collaborative research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target for one of the deadliest forms of cancer among men.

7 Sep 2018

Endocrine Society announces winners of prestigious 2019 Laureate Awards

The Endocrine Society today announced it has chosen 13 leading endocrinologists as winners of its prestigious 2019 Laureate Awards, the top honors in the field.

6 Sep 2018

Good skin care practices can help teens to battle stubborn acne

Being a teenager can be tough. Teens must manage high school and the pressures of adolescence while at the same time battling stubborn acne.

6 Sep 2018

MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

The Muscular Dystrophy Association today announced the award of 34 new grants totaling more than $9.9 million for its summer round of funding. These new grants represent a continued commitment by MDA to fund groundbreaking research that will accelerate treatments and cures for the more than 40 diseases in its program.

24 Aug 2018

New research confirms link between DDT exposure and autism

The results of a national birth cohort study published today provide biomarker evidence that DDT increases the risk of autism.

15 Aug 2018

Study: Blood test can predict response of advanced prostate cancer patients to treatments

An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Center, the Royal Marsden and Epic Sciences is one of the first to demonstrate that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival.

25 Jul 2018

Australian-led global guidelines for diagnosis and treatment of women with PCOS

Australian led global guidelines for the diagnosis and treatment of the primary cause of infertility in women will be published simultaneously in three international journals, supported by a suite of health professional and patient resources to improve health outcomes for women with PCOS.

23 Jul 2018

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common.

20 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018