Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Scientists reveal how miRNAs shape cancer and offer new paths for treatment

Review explores how microRNAs (miRNAs) interact in cancer development, their potential in diagnosis, and innovative therapeutic strategies, including overcoming chemotherapy resistance.

20 Oct 2024

Zebrafish could be used to explore the underlying mechanisms of Nager syndrome

Nager syndrome, or NS, is a rare genetic disease that affects the development of the face and limbs, usually causing anomalies in the bone structures of the jaws, cheeks, and hands.

16 Oct 2024

Harnessing the power of miRNA for cancer diagnosis and treatment

This study is led by Dr. Shiwei Duan (Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China). His team analyzed literature on miRNA, summarizing the close relationship between these small molecules and cancer. miRNA is a type of non-coding RNA that does not encode proteins, but can target more than 60% of human protein-coding genes.

15 Oct 2024

Promising new treatment strategy for type 2 diabetes

Groundbreaking research presented today at UEG Week 2024 reveals a promising new treatment strategy for type 2 diabetes (T2D) that could significantly reduce or even eliminate the need for insulin therapy.

14 Oct 2024

The new science behind the health benefits of caffeine

A study reveals caffeine's potential to enhance heart health by improving endothelial function in systemic lupus erythematosus patients through EPC survival.

9 Oct 2024

Mosaic Therapeutics appoints Dr Barry Davies as CSO

Dr. Barry Davies joins Mosaic Therapeutics as CSO, bringing 25 years of drug discovery expertise to advance targeted oncology therapies and precision medicine.

8 Oct 2024

New insights on 5-fluorouracil's mechanism in different cancers

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

7 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Inflammatory proteins linked to higher risk of endometrial cancer

Study identifies key inflammatory and immune response proteins linked to endometrial cancer risk through both observational and Mendelian Randomization analyses, revealing the roles of IL-6 and HSD11B1.

1 Oct 2024

Traditional Chinese medicine shows potential in cancer treatment

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, all of which have significantly contributed to improving patient survival.

1 Oct 2024

New pipeline of drug candidates offers hope for effective MASLD treatments

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

25 Sep 2024

Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

Impact of oxidative stress, gut, and diet on attention deficit hyperactivity disorder pathophysiology

Oxidative stress and gut microbiome interactions are key in ADHD pathogenesis, with diet playing a crucial role in managing symptoms and improving outcomes.

18 Sep 2024

Review highlights mitochondrial dysfunction in cholestatic liver injury

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats.

16 Sep 2024

PPARs and PROTACs: A new strategy in cancer therapeutics

The growing challenge in cancer therapy lies in overcoming tumor heterogeneity, drug resistance, and associated side effects.

13 Sep 2024

The potential benefits of aged black garlic on inflammation and prostate cancer

Researchers investigate the anti-inflammatory and anti-prostate cancer properties of aged black garlic extract.

13 Sep 2024

Pyroptosis found to promote wound healing and tissue repair

A study by the team of Prof. Kodi Ravichandran (VIB-UGent Center for Inflammation Research) and colleagues found that pyroptosis, a form of programmed cell death traditionally thought to be purely inflammatory, also plays a crucial role in promoting healing and tissue repair.

11 Sep 2024

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

Advances in tissue engineering and 3D bioprinting have revolutionized the development of physiologically relevant 3D in vitro cancer models, offering a closer representation of the tumor microenvironment (TME) and enabling high-throughput drug screening.

From Carcinotech 30 Aug 2024

COVID-19 linked to increased risk of hearing loss in young adults, study finds

Researchers in South Korea found that young adults who recovered from COVID-19 are at significantly higher risk of experiencing hearing loss and sudden sensorineural hearing loss compared to those who never had the virus.

28 Aug 2024

A study confirms that smoking significantly increases the risk of stroke

Findings indicate smoking elevates stroke risk, particularly in older males with comorbidities, underscoring the need for targeted prevention strategies.

28 Aug 2024