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New research suggests that Alzheimer's gene may begin to affect brains in childhood

People who carry a high-risk gene for Alzheimer's disease show changes in their brains beginning in childhood, decades before the illness appears, new research from the Centre for Addiction and Mental Health suggests.

3 Dec 2013

Risk factors for Alzheimer's disease

Alzheimer's disease has joined cancer at the top of the list of feared diagnoses, and although Alzheimer's does have the potential to devastate millions of patients and families, there are reasons for hope - and possibly opportunities to reduce risk or alter the course of disease progression, according to Keith Black, MD, professor and chair of the Department of Neurosurgery at Cedars-Sinai.

26 Nov 2013

Viewpoints: Obamacare has resisted death throes before; website success stories from 3 governors; health law taking a toll on choice of doctors in Medicare Advantage

The first time Obamacare seemed finished, doomed, doornail-dead, the voters of Massachusetts played the would-be executioner. In January 2010, they sent a pickup-driving Republican to the Senate to fill Ted Kennedy's seat, apparently depriving the health care bill of its crucial 60th vote and sending Democrats scrambling for a Plan B. ... the deeper force at work, the reason that these near-death experiences keep happening, isn't a website or a broken presidential promise. It's a problem inherent to contemporary liberalism, which is that liberals' proudest achievement, the modern welfare state, tends to resist, corrupt and baffle their efforts at comprehensive reform (Ross Douthat, 11/16).

19 Nov 2013

Scientists receive $1.2M grants to explore development of AD in individuals with Down syndrome

Donna Wilcock of the University of Kentucky Sanders-Brown Center on Aging is the lead investigator on a recently-funded project exploring the links between Alzheimer's disease and Down Syndrome. Elizabeth Head, also of Sanders-Brown Center on Aging, is a co-investigator on the project.

10 Nov 2013

Study: Glucose levels, vascular damage contribute to dementia

High blood-sugar levels, such as those linked with Type 2 diabetes, make beta amyloid protein associated with Alzheimer's disease dramatically more toxic to cells lining blood vessels in the brain, according to a new Tulane University study published in latest issue of the Journal of Alzheimer's Disease.

29 Oct 2013

Plant Sterols prove to be better cholesterol in Alzheimer`s disease

"Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, they can in principal influence metabolic processes, where cholesterol is involved," explained Marcus Grimm, Head of the Experimental Neurology Laboratory at Saarland University. "Because they also lower cholesterol levels, they are extensively used in the food industry and as dietary supplements."

25 Oct 2013

Just 13 days in space may cause changes in eye structure, gene expression

Just 13 days in space may be enough to cause profound changes in eye structure and gene expression, report researchers from Houston Methodist, NASA Johnson Space Center, and two other institutions in the October 2013 issue of Gravitational and Space Research.

25 Oct 2013

Study shows plant sterols appear to prevent onset of Alzheimer's disease

It's no secret that many of the phytochemicals in fruit and vegetables have a positive effect on our health. For instance, plant sterols (also known as phytosterols) help to lower cholesterol levels. According to a new study by researchers at Saarland University, they also appear to prevent the onset of Alzheimer's disease.

24 Oct 2013

Newly discovered proteins in spinal fluid can serve as markers for Alzheimer's disease

23 Oct 2013

Shorter sleep duration, poorer sleep quality may impact Alzheimer's disease onset and progression

Poor sleep quality may impact Alzheimer's disease onset and progression. This is according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health who examined the association between sleep variables and a biomarker for Alzheimer's disease in older adults.

22 Oct 2013

Study: Sleep allows brain to flush out damaging molecules linked with neurodegeneration

A good night's rest may literally clear the mind. Using mice, researchers showed for the first time that the space between brain cells may increase during sleep, allowing the brain to flush out toxins that build up during waking hours.

18 Oct 2013

Proteins in CSF predict cognitive impairment before onset of disease

Johns Hopkins researchers say that by measuring levels of certain proteins in cerebrospinal fluid (CSF), they can predict when people will develop the cognitive impairment associated with Alzheimer's disease years before the first symptoms of memory loss appear.

17 Oct 2013

Elderly people with hardening of arteries are more likely to have beta-amyloid plaques in brain

Even for elderly people with no signs of dementia, those with hardening of the arteries are more likely to also have the beta-amyloid plaques in the brain that are a hallmark of Alzheimer's disease, according to a study published in the October 16, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

17 Oct 2013

Study shows beneficial effects of mild hypothermia on cellular responses to TBI

Moderate reductions in body temperature can improve outcomes after a person suffers a traumatic brain injury (TBI). New research that identifies positive effects of mild hypothermia on brain tissue is presented in an article published in Therapeutic Hypothermia and Temperature Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

24 Sep 2013

Study shows distinct molecular structures may predominate in brains of Alzheimer's patients

Alzheimer's disease is thought to be caused by the buildup of abnormal, thread-like protein deposits in the brain, but little is known about the molecular structures of these so-called beta-amyloid fibrils.

13 Sep 2013

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Researchers at Emory University School of Medicine's Alzheimer's Disease Research Center have identified a previously unrecognized type of pathology in the brains of patients with Alzheimer's disease.

11 Sep 2013

UCLA study suggests third possible cause for AD: Iron accumulation

Alzheimer's disease has proven to be a difficult enemy to defeat. After all, aging is the No. 1 risk factor for the disorder, and there's no stopping that.

21 Aug 2013

Glucose intolerance, insulin resistance not associated with pathological features of AD

Glucose intolerance or insulin resistance do not appear to be associated with pathological features of Alzheimer disease (AD) or detection of the accumulation of the brain protein β-amyloid (Αβ), according to a report published by JAMA Neurology, a JAMA Network publication.

30 Jul 2013

Results of post-mortem brain tissue study using Navidea's NAV4694 imaging agent presented at AAIC 2013

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that researchers at McGill Center for Studies in Aging, Douglas Research Institute and Montreal Neurological Institute presented results of a post-mortem brain tissue study using Navidea's investigational Fluorine-18 labeled β-amyloid imaging agent, NAV4694, during the Alzheimer's Association International Conference in Boston, MA.

23 Jul 2013

New data identifies specific cellular pathways by which RNS60 impacts Alzheimer's Disease

On Wednesday Revalesio Corporation presented new data at the Alzheimer's Association International Conference that identifies the specific cellular pathways by which Revalesio's lead investigational product, RNS60, impacts Alzheimer's Disease. This research, conducted in partnership with Rush University Medical Center, investigates a new category of therapeutics using Revalesio's novel nanotechnology platform.

19 Jul 2013