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Computer program could help dementia patients manage their disease

Researchers at Weill Cornell Medical College have developed a computer program that has tracked the manner in which different forms of dementia spread within a human brain. They say their mathematic model can be used to predict where and approximately when an individual patient's brain will suffer from the spread, neuron to neuron, of "prion-like" toxic proteins -- a process they say underlies all forms of dementia.

22 Mar 2012

Technique developed to identify rogue clustering proteins in brain diseases

Australian researchers have developed a novel technique that tracks proteins “behaving badly” and may have found a way that leads to new treatments for brain disease. The team believes the discovery could help in the development of drugs to treat diseases such as Alzheimer's, Parkinson's and Huntington's.

19 Mar 2012

Measuring wellbeing in Huntington’s disease

The new tool, the first Huntington’s disease-specific quality of life instrument of its kind, aims to fully capture the impact of this complex disease on the everyday life of sufferers. By using this new tool to more accurately measure the impact of Huntington’s and also any effect of therapeutic interventions, scientists will be in a better position to evaluate the usefulness of interventions on patients’ everyday quality of life to see if there is actually a practical benefit. It is hoped that in this way, this tool will lead to more effective treatments.

8 Mar 2012

AAN to honor Tokyo neurologist with Potamkin Prize for AD research

The American Academy of Neurology is awarding its 2012 Potamkin Prize for Research in Pick's, Alzheimer's and Related Diseases to Takeshi Iwatsubo, MD, PhD, with the University of Tokyo School of Medicine. Iwatsubo will receive the award during the Academy's 64th Annual Meeting, April 21-28, 2012, in New Orleans.

22 Feb 2012

ALS Association, AAN to honor KCL neurologist with Essey Award

The American Academy of Neurology and the ALS Association are awarding the 2012 Sheila Essey Award: An Award for ALS Research to Christopher Shaw, MBChB, MD, FRACP, with the Institute of Psychiatry at King's College London. Shaw will receive the award during the Academy's 64th Annual Meeting, April 21-28, 2012, in New Orleans.

22 Feb 2012

AAN, National MS Society to honor Cleveland Clinic researcher with John Dystel Prize

The American Academy of Neurology and the National Multiple Sclerosis Society are awarding the 2012 John Dystel Prize for MS Research to Richard M. Ransohoff, MD, with the Cleveland Clinic. Ransohoff, a member of the American Academy of Neurology and Associate Editor of Neurology, the Academy's medical journal, will receive the award at the Academy's 64th Annual Meeting in New Orleans, April 21-28, 2012.

22 Feb 2012

Cancer drug bexarotene effective in mouse model of Alzheimer’s

Case Western Reserve University School of Medicine neuroscientist Gary Landreth and colleagues reported Thursday that the drug - bexarotene quickly cleared away beta-amyloid plaque, believed to cause the cognitive deficits of Alzheimer's disease, from the brains of genetically engineered mice.

12 Feb 2012

Anabolic steroids do not appear to contribute to CTE

Anabolic steroids don't appear to contribute to degenerative brain disease caused by repeated head trauma in athletes, according to a study in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

20 Jan 2012

AAN neurologist receives prestigious award at Palatucci Advocacy Leadership Forum

The American Academy of Neurology(AAN) has named neurologist Constantine Moschonas, MD, of Scottsdale, Ariz., as the AAN Donald M. Palatucci Advocacy Leadership Forum Advocate of the Year. Moschonas received his award at the Palatucci Advocacy Leadership Forum on January 14, 2012, in Austin, Texas, for his outstanding work in raising awareness about brain diseases such as Alzheimer's disease, stroke, autism, Parkinson's disease and multiple sclerosis.

17 Jan 2012

Nicotine patch may help those with mild dementia

The nicotine patch designed to help people quit smoking can also improve memory in older adults with mild cognitive impairment, or MCI, a small clinical trial found.

10 Jan 2012

New evidence on heading and risk of brain injury in soccer

Could heading the ball in soccer lead to degenerative brain disease, like that seen in athletes in other sports? That's the question addressed by a review in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

10 Jan 2012

Researchers uncover exact function of LARGE enzyme linked with MD

Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 in the journal Science,, could be used to develop rapid, large-scale testing of potential muscular dystrophy therapies.

10 Jan 2012

Alkermes commences ALKS 9070 phase 3 clinical trial for schizophrenia

Alkermes plc today announced the initiation of a phase 3 clinical trial of ALKS 9070 for the treatment of schizophrenia. ALKS 9070, a proprietary Alkermes molecule, is designed to provide patients with once-monthly dosing of a medication that, once in the body, converts into aripiprazole, a molecule that is commercially available under the name ABILIFY for the treatment of a number of central nervous system disorders.

19 Dec 2011

Alzheimer's disease affects women more than men

Many women suffer memory loss and/or confusion at some point in their lives, but as many as 5 million Americans suffer from a much more serious disease, Alzheimer's. According to statistics from the National Institute on Aging, Alzheimer's disease is the most common form of dementia in older people. Alzheimer's is a progressive brain disease; it is irreversible and causes a decline in memory and cognitive skills.

1 Dec 2011

Direct link between fish consumption, brain structure and Alzheimer's risk

People who eat baked or broiled fish on a weekly basis may be improving their brain health and reducing their risk of developing mild cognitive impairment (MCI) and Alzheimer's disease, according to a study presented today at the annual meeting of the Radiological Society of North America.

30 Nov 2011

Alzheimer’s disease progression and body weight may be linked: Study

There have been studies that show that people who are overweight in middle age are more likely to develop Alzheimer's disease decades later than people at normal weight. However some studies also show that people in the earliest stages of Alzheimer's disease are more likely to have a lower body mass index (BMI).

22 Nov 2011

Restoration of dopamine levels could potentially prevent drug abuse

Portuguese researchers have discovered that rats exposed before birth to glucocorticoids not only show several brain abnormalities similar to those found in addicts, but become themselves susceptible to addiction (the glucorticoids, which are stress hormones, were used to mimic pre-natal stress).

1 Nov 2011

Researchers discover biomarker for earlier diagnosis of MS

Researchers from the Department of Neurology at NYU Langone Medical Center identified for the first time that changes in the tissue located at the junction between the outer and inner layers of the brain, called "blurring", may be an important, non-invasive biomarker for earlier diagnosis and the development of new therapies for degenerative brain conditions, such as multiple sclerosis.

1 Nov 2011

JHU, Eisai enter drug-discovery research collaboration for brain disorders

The Johns Hopkins University (JHU) has entered into a drug-discovery research collaboration with Eisai, a pharmaceutical company based in Tokyo, to develop proprietary small-molecule drugs for a range of brain conditions such as schizophrenia, pain, brain tumors and Alzheimer's disease.

20 Oct 2011

October is designated as Lewy Body Dementia month

The month of October is designated as Lewy Body Dementia month. Lewy body dementia (LBD) is a degenerative brain disease that progressively impairs thinking and movement, while impacting behavior and sleep. Although it affects an estimated 1.3 million people in the U.S., LBD is under-recognized, under-diagnosed and under-treated. It is most often misdiagnosed as Alzheimer's or Parkinson's disease.

13 Oct 2011