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Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Human lungs rejected for transplant can be recovered using cross-circulation with pigs

A new experiment by researchers at the Columbia Engineering and Vanderbilt University may have the solution to this long-standing problem. The team revived and repaired the damaged lungs by cross-circulation support of the whole lungs outside the body using the circulatory system with that of a living pig.

14 Jul 2020

Severely injured donor lungs can be successfully recovered outside the body

Respiratory disease is the third leading cause of death worldwide, and lung transplantation is still the only cure for patients with end-stage lung disease.

13 Jul 2020

Molecular imaging reveals inter-organ communication between the heart and kidneys after heart attack

Whole body positron emission tomography (PET) has, for the first time, illustrated the existence of inter-organ communication between the heart and kidneys via the immune system following acute myocardial infarction, or heart attack.

13 Jul 2020

New drug discovery shows promise in fighting acute respiratory illnesses

A collaboration between the University of Toronto's Faculty of Dentistry and the National Jewish Health in Denver -- the top-ranked respiratory research hospital in the U.S. -- has yielded a new drug discovery that could be useful to combat inflammation of all varieties and shows promise in fighting acute respiratory illnesses such as COVID-19.

2 Jul 2020

Scottish biotech Invizius seeks Series A funding for breakthrough in dialysis treatment

Scottish biotech firm Invizius, which has developed a technology aimed at reducing long-term side effects and health complications from dialysis treatment, is seeking Series A funding after undergoing promising safety trials.

22 Jun 2020

Study investigates potential of adoptive cell therapy in combination with checkpoint inhibitors

Volume 11, Issue 22 of @Oncotarget reported that there are rationale and evidence supporting immune therapy in Ovarian Cancers.

10 Jun 2020

CSL Behring and Seattle Children's partner to develop gene therapies for primary immunodeficiency diseases

Seattle Children's Research Institute, one of the top pediatric research institutions in the world, and global biotechnology leader CSL Behring announced a strategic alliance to develop stem cell gene therapies for primary immunodeficiency diseases.

2 Jun 2020

UZH researchers develop new X-ray contrast agent for high-resolution vascular imaging

Various diseases in humans and animals - such as tumors, strokes or chronic kidney disease - damage the blood vessels. Capillaries, the smallest blood vessels in the body, are particularly affected.

26 May 2020

Biologic drug can help treat contact dermatitis

APOSEC it is a biologic wound-healing agent developed by thoracic surgeon Hendrik Jan Ankersmit from MedUni Vienna.

15 May 2020

Human to Labskin Skin Models for Dermatology Research

A Human Skin Equivalent (HSE) skin model used for dermatology research, made from the same primary human cells but grown to a defined specification in a laboratory and not as complex as Human skin, lacking hair follicles and immune cells.

6 May 2020

New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Intestinal stem cell metabolism is facilitated by mitochondria - the in-cell power plants. Chronic inflammation processes inhibit the cells' metabolism and lead to functional loss of these stem cells.

15 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

Research may pave the way to developing effective treatments for puerperal sepsis

Puerperal sepsis, also known as childbed fever, is the leading cause of maternal deaths. In this novel study in The American Journal of Pathology, published by Elsevier, scientists report on the discovery of group A streptococcus (GAS) surface proteins involved in female reproductive tract infections such as puerperal sepsis that may pave the way to developing vaccines and more effective treatments.

19 Mar 2020

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences, Dana-Farber Cancer Institute, and Harvard's Department of Stem Cell and Regenerative Biology, announce the formation of a new NIH-funded Immuno-Engineering to Improve Immunotherapy Center.

7 Mar 2020

UConn team discovers a population of stem cells with ability to generate new bone

A population of stem cells with the ability to generate new bone has been newly discovered by a group of researchers at the UConn School of Dental Medicine.

5 Mar 2020

Revolutionary SPion technology enables remote analysis with mass spectrometry

Trace Matters Scientific today introduced SPion -a revolutionary technology that enables the world's most sensitive and versatile remote analysis with mass spectrometry.

16 Feb 2020

Trinity bioengineers take crucial step towards mending a broken heart

Bioengineers from Trinity College Dublin, Ireland, have developed a prototype patch that does the same job as crucial aspects of heart tissue.

13 Feb 2020

LBIC acquires MILabs' new diagnostic X-Ray CT system to extend its preclinical imaging capabilities

The Bioimaging Center of Lund University is a leading trans-faculty research center that houses a wide range of advanced preclinical and clinical imaging equipment. To further extend its preclinical imaging capabilities, LBIC recently acquired a MILabs uCT diagnostic X-ray CT system.

10 Jan 2020

New radiotracer can provide insights into how the heart recovers after myocardial infarction

Insights into how the heart recovers after myocardial infarction (heart attack) can be obtained with a new radiotracer that targets fibroblast activity prior to it causing permanent damage.

2 Jan 2020